Patents by Inventor Raphael Tripier

Raphael Tripier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof
    Patent number: 10434199
    Abstract: Chelates resulting from the complexation of picolinate cross-bridged cyclams of formula (I), wherein n and the substituents L1-L4 and R1-R5 are as defined, with metallic cations. Picolinate cross-bridged cyclam ligands of formula (I), the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents are also described.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: October 8, 2019
    Assignees: UNIVERSITÉ DE BRETAGNE OCCIDENTALE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Raphael Tripier, Zakaria Halime
  • Chelates of lead (II) and bismuth (III) based on trans-di-N-picolinate tetraazacycloalkanes
    Patent number: 9884881
    Abstract: The invention relates to a chelate resulting from the complexing of a trans-di-N-picolinate tetraazacycloalkane ligand with a metal cation, said ligand corresponding to formula (A) wherein n is equal to 0 or to 1, R is H or a C1-C18 alkyl radical, and R? is H or a C1-C18 alkyl radical, said metal cation being a cation of a metal selected from the group consisting of lead (II) and bismuth (III). The invention is applicable in the field of lead trapping and alpha-radioimmunotherapy.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: February 6, 2018
    Assignees: CNRS—Centre National de la Recherche Scientifique, Universite de Bretagne Occidentale
    Inventors: Raphael Tripier, Carlos Platas-Iglesias, Luis Lima, Maryline Beyler
  • BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF
    Publication number: 20170326261
    Abstract: Disclosed are chelates resulting from the complexation of bifunctional do2pa derivatives ligands of formula (I), wherein the substituents R1, R1?, R2, R2?, R3, R3?, L1, L1?, L2 and L2? are defined as in the claims, with metallic cations, especially Pb(II) and Bi(III). Also disclosed are bifunctional do2pa derivatives ligands of formula (I), as well as the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents.
    Type: Application
    Filed: December 4, 2015
    Publication date: November 16, 2017
    Inventors: Fatima OUKHATAR, Maryline BEYLER, Raphael TRIPIER
  • PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF
    Publication number: 20160287733
    Abstract: Chelates resulting from the complexation of picolinate cross-bridged cyclams of formula (I), wherein n and the substituents L1-L4 and R1-R5 are as defined, with metallic cations. Picolinate cross-bridged cyclam ligands of formula (I), the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents are also described.
    Type: Application
    Filed: November 12, 2014
    Publication date: October 6, 2016
    Inventors: Raphael TRIPIER, Zakaria HALIME
  • Chelates of Lead (II) and Bismuth (III) Based on Trans-Di-N-Picolinate Tetraazacycloalkanes
    Publication number: 20160115187
    Abstract: The invention relates to a chelate resulting from the complexing of a trans-di-N-picolinate tetraazacycloalkane ligand with a metal cation, said ligand corresponding to formula (A) wherein n is equal to 0 or to 1, R is H or a C1-C18 alkyl radical, and R? is H or a C1 -C18 alkyl radical, said metal cation being a cation of a metal selected from the group consisting of lead (II) and bismuth (III). The invention is applicable in the field of lead trapping and alpha-radioimmunotherapy.
    Type: Application
    Filed: June 5, 2014
    Publication date: April 28, 2016
    Inventors: RAPHAEL TRIPIER, CARLOS PLATAS-IGLESIAS, LUIS LIMA, MARYLINE BEYLER
  • Methods for preparing functional tetraazacycloalkane compounds using a specific cyclic bisaminal compound
    Patent number: 9315511
    Abstract: Special C-functionalized cyclic bisaminal compounds having formula (I) or (II), their salts or solvates, methods for their preparation, their uses, and methods for preparing functional tetraazacycloalkane compounds implementing such cyclic bisaminal compounds.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: April 19, 2016
    Assignees: UNIVERSITE DE BRETAGNE OCCIDENTALE, CNRS—CENTRE NATIONAL DE LA RECHERCHE
    Inventors: Raphael Tripier, Nathalie Camus
  • Methods for Preparing Functional Tetraazacycloalkane Compounds using a Specific Cyclic Bisaminal Compound
    Publication number: 20140323717
    Abstract: Special C-functionalized cyclic bisaminal compounds having formula (I) or (II), their salts or solvates, methods for their preparation, their uses, and methods for preparing functional tetraazacycloalkane compounds implementing such cyclic bisaminal compounds.
    Type: Application
    Filed: November 16, 2012
    Publication date: October 30, 2014
    Inventors: Raphael Tripier, Nathalie Camus