Patents by Inventor Raquel Martins

Raquel Martins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11672839
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular respiratory bacterial infections such as bacterial pneumonia. More specifically, the present invention is directed to novel bacteriophage strains, and products and cocktails thereof, including F99/10, F110/10, F27/12, Psa_F83/13, Psa_F95/13, F391/08, Kle_F92/15, Kle_F105/15, Kle_F134/15, Kle_F141/15, as well as variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including respiratory infections caused by, e.g., Pseudomonas aeruginosa and/or Klebsiella pneumoniae. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics or other standard and non-standard therapies for respiratory infections.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: June 13, 2023
    Assignees: TECHNECHNOPHAGE, INVESTIGACAO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA, TECNIFAR—INDUSTRIA TECNICA FARMACEUTICA, SA
    Inventors: Sofia Valker Córte-Real, Miguel Ângelo Costa Garcia, Clara Isabel Rodrigues Leandro, Ana Raquel Martins Barbosa
  • Publication number: 20210187046
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular respiratory bacterial infections such as bacterial pneumonia. More specifically, the present invention is directed to novel bacteriophage strains and cocktails thereof, as well as variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including respiratory infections caused by, e.g., Pseudomonas aeruginosa and/or Klebsiella pneumoniae. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics or other standard and non-standard therapies for respiratory infections.
    Type: Application
    Filed: December 18, 2020
    Publication date: June 24, 2021
    Applicants: TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA, TECNIFAR - INDUSTRIA TECNICA FARMACEUTICA, S.A.
    Inventors: Clara Isabel Rodrigues Leandro, Ana Raquel Martins Barbosa, Daniela Jones Dias, Ana Filipa Martins, Miguel Ângelo da Costa Garcia, Sofia Volker Côrte-Real
  • Publication number: 20190290709
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular respiratory bacterial infections such as bacterial pneumonia. More specifically, the present invention is directed to novel bacteriophage strains, and products and cocktails thereof, including F99/10, F110/10, F27/12, Psa_F83/13, Psa_F95/13, F391/08, Kle_F92/15, Kle_F105/15, Kle_F134/15, Kle_F141/15, as well as variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including respiratory infections caused by, e.g., Pseudomonas aeruginosa and/or Klebsiella pneumoniae. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics or other standard and non-standard therapies for respiratory infections.
    Type: Application
    Filed: December 4, 2017
    Publication date: September 26, 2019
    Inventors: Sofia Valker Côrte-Real, Miguel Ângelo Costa Garcia, Clara Isabel Rodrigues Leandro, Ana Raquel Martins Barbosa
  • Patent number: 9737579
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: August 22, 2017
    Assignees: Technophage, Investigacao E Desenvolvimento Em Biotecnologia, SA, Tecnifar—Industria Tecnica Farmaceutica, S.A.
    Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
  • Publication number: 20160317590
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.
    Type: Application
    Filed: July 22, 2016
    Publication date: November 3, 2016
    Inventors: Miguel Ångelo DA COSTA GARCIA, Carlos Jorge SOUSA DE SÃO JOSÉ, Clara Isabel RODRIGUES LEANDRO, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel MARTINS BARBOSA
  • Patent number: 9399049
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: July 26, 2016
    Assignees: Technophage, Investigacao E Desenvolvimento Em Biotecnologia, SA, Tecnifar-Industria Tecnica Farmaceutica, S.A.
    Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
  • Publication number: 20160074446
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.
    Type: Application
    Filed: November 17, 2015
    Publication date: March 17, 2016
    Inventors: Miguel Ângelo DA COSTA GARCIA, Carlos Jorge SOUSA DE SÃO JOSÉ, Clara Isabel RODRIGUES LEANDRO, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel MARTINS BARBOSA
  • Patent number: 9222077
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: December 29, 2015
    Assignees: Tecnifar—Industria Tecnica Farmaceutica, S.A., Technophage, Investigacao E Desenvolveimento Em Biotecnologia, SA
    Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
  • Publication number: 20140079671
    Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.
    Type: Application
    Filed: September 19, 2011
    Publication date: March 20, 2014
    Applicants: TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA, TECNIFAR-INDÚSTRIA TÉCNICA FARMACÊUTICA, S.A.
    Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
  • Publication number: 20100318187
    Abstract: A method for producing a polymeric surface-structured substrate includes: (a) preparing a first precursor substrate that is nanostructured on at least one surface with inorganic nanoparticles, (b) coating a hardenable substrate material for a second substrate different from the first precursor substrate material onto the nanostructured surface of the precursor substrate, wherein the hardenable substrate material includes cross-linkable monomeric, oligomeric or polymeric starting components for producing a polymeric substrate, (c) hardening the hardenable substrate material to obtain a polymeric substrate, and (d) separating the precursor substrate from the polymeric substrate as a result of which a polymeric substrate nanostructured with nanoparticles and including a polyurethane is obtained.
    Type: Application
    Filed: June 11, 2010
    Publication date: December 16, 2010
    Applicant: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Sebastian Kruss, Joachim P. Spatz, Raquel Martin
  • Publication number: 20080185250
    Abstract: A case for containing at least partly compressible articles comprises an outer shell which can be opened and closed and defines a cavity therewithin, and having an attachment member or members secured to the outer shell inside the cavity. A number of compression bags are contained within the shell cavity and are detachably retained by the attachment members such as to maintain a relative position with respect to one another within the case. Each of the compression bags includes is air impervious when sealed and can received the articles within the enclosure defined therein, and includes a one-way valve allowing air to be removed from the enclosure within the bag, thereby creating at least a partial vacuum in the enclosure which compresses the articles within the bag.
    Type: Application
    Filed: December 12, 2007
    Publication date: August 7, 2008
    Inventors: Norberto Martins, Raquel Martins