Abstract: The present invention relates to a precipitation polymerization method for obtaining spherical polymer particles of a copolymer with statistical topology and chemical structure (acid monomer selected from acrylic or methacrylic)-co-(cross-linker selected from acrylic or methacrylic)-co-(hydroxylated monomer selected from acrylic or methacrylic) and which are functionalised with a divalent cation selected from Zn+2, Ca+2, Mg+2 and Sr+2 and/or an antibacterial agent. The invention also relates to said polymeric particles. The invention further relates to a composition comprising the polymeric particles and to the use of the particles to produce a drug.

Abstract: Present invention refers to tooth re-mineralization materials incorporating calcium phosphates and calcium-free silicon compounds. Materials are efficacious in re-mineralization of teeth and occlusion of exposed dentinal tubules either when used alone or in dentifrice preparations for oral healthcare. Preferred calcium phosphates include anhydrous dicalcium phosphate, dicalcium phosphate dihydrate, hydroxyapatite and amorphous calcium phosphate that can incorporate partial substitutions of calcium by divalent metallic ions such as Mg++, Zn++, Ba++, Fe++, Sn++ and Sr++. Preferred calcium-free silicon compounds include silicon oxide, silica gel, methasilicic acid, orthosilicic acid, silicic acid, and combinations thereof.