Abstract: This invention relates to topical compositions of an antibacterial benzoquinolizine-2-carboxylic acid, incorporated either as the single therapeutic ingredient in hitherto undescribed pharmaceutical compositions, or as an ingredient in novel combination with at least one agent selected from a retinoid, an antifungal agent, another antibacterial compound and/or a steroid/non-steroid anti-inflammatory agent, to processes for preparation of the compositions, to use of the compositions in preparation of a medicament, and to a method of therapeutic or prophylactic use of such a composition for the treatment of dermal, ophthalmic, otic and nasal infections, with or without attendant inflammation.

Abstract: Immunomodulating pharmacologically and biologically active compositions containing a standardized extract of the plant Tinosporia cordifolia, a process for their preparation and their use in dosage forms for healthcare, nutrition and treatment of disorders modulated by the immune system are described. The process includes preparation of an extract from plant parts of Tinosporia cordifolia and standardization of the extract by phagocytosis and LC-MS single ion recording assays. Methods of treating immunomodulatory deficiencies in healthcare are also disclosed using the compositions.