Abstract: In one embodiment, a system for managing communication connections in a virtualization environment includes a plurality of host machines implementing a virtualization environment, wherein each of the host machines includes a hypervisor, at least one user virtual machine (user VM), and a distributed file server that includes file server virtual machines (FSVMs) and associated local storage devices. Each FSVM and associated local storage device are local to a corresponding one of the host machines, and the FSVMs conduct I/O transactions with their associated local storage devices based on I/O requests received from the user VMs. Each of the user VMs on each host machine sends each of its representative I/O requests to an FSVM that is selected by one or more of the FSVMs for each I/O request based on a lookup table that maps a storage item referenced by the I/O request to the selected one of the FSVMs.

Abstract: A method for charging a battery pack via an offboard energy source uses an interleaved boost converter and closed-loop control. The energy source outputs a charging current via a DC charge port during a direct current fast-charging (DCFC) process. A controller detects a voltage disparity condition in which a voltage capability of the battery pack exceeds a voltage capability of the energy source. In response to this condition, a rise of the charging current over time is recorded as a current trajectory and an open-loop equivalent time constant is extracted from the current trajectory. A time constant of the PI control block is set substantially equal to the equivalent time constant. The PIM is controlled in closed-loop using proportional-integral control. The charging current is controlled in a continuous current conduction mode during the DCFC process.

Abstract: This is a method and a system for designing a personalized therapeutic intervention for an individual. Each individual has a unique composition of microbiome in the gut, one probiotic or dietary regimen may not have same efficacy in different individuals. The disclosure recommends a personalized therapeutic intervention for improving gut health of an individual by designing personalized therapeutics and diet based on functions of microbiome. The personalized therapeutic intervention is recommended based on several steps including generating a set of knowledge bases, identifying a change in the gut health of an individual by monitoring the gut samples and recommending a personalized therapeutic intervention. The personalized therapeutic intervention comprises at least one of a prebiotic, a probiotic and an optimized diet, wherein the optimized diet is estimated based on optimizing a gut food score, where the gut food score is computed based on the change in the gut health of an individual.

Abstract: Aspects of the subject disclosure may include, for example, constructing a vehicle record for a driverless vehicle that indicates capabilities of the vehicle for responding in an emergency; receiving an alert regarding an incident; analyzing a database to identify available vehicles for responding to the incident; selecting a vehicle from the available vehicles in accordance with selection criteria including a current vehicle location and capabilities of the vehicle; directing the selected vehicle to the incident location; directing the selected vehicle to perform one or more actions to respond to the incident; receiving data from the selected vehicle regarding performance of the actions; analyzing the data to evaluate the performance; and generating a report of the incident including an indication of the performance. Other embodiments are disclosed.

Abstract: Methods of treating cancer in a patient by administering 5-(1H-indol-3-yl)-1,3-substituted pyrimido[4,5-d]pyrimidine-2,4,7(1H,3H,8H)-trione to a patient in need thereof.

Abstract: A system for use with a direct current fast-charging (DCFC) station includes a controller and battery system. The battery system includes first and second battery packs, and first, second, and third switches. The switches have ON/OFF conductive states commanded by the controller to connect the battery packs in a parallel-connected (P-connected) or series-connected (S-connected) configuration. An electric powertrain with one or more electric machines is powered via the battery system. First and second charge ports of the system are connectable to the station via a corresponding charging cable. The first charge port receives a low or high charging voltage from the station. The second charge port receives a low charging voltage. When the station can supply the high charging voltage to the first charge port, the controller establishes the S-connected configuration via the switches, and thereafter charges the battery system solely via the first charge port.

Abstract: The present invention relates to systems and methods for automated interpretable and generalizable biological morphological profiling. The method for identifying single-cell morphological profiling based on deep learning includes collecting and pre-processing at least one single-cell image data; training Variational Autoencoder (VAE) by defining an arbitrary dimension size of a latent space; distilling a learnt latent space from the VAE to Generative Adversarial Network (GAN) and training a generator-discriminator combination within the GAN; generating a realistic image aligned with the learnt latent space; and interpreting data by incorporating statistical variance analysis and hierarchical clustering.

Abstract: An autonomous system for detecting primary site failure on a Replication Data Facility (RDF) and automating failover to a destination site includes a replication data facility health monitor on a destination site that monitors a plurality of health indicators of the primary site. Example health indicators include RDF session state of RDF sessions on the replication data facility, and reachability of a set of IP addresses. Example IP addresses include an IP address of a cluster master node on the primary site, IP addresses of all of the cluster nodes on the primary site, and IP addresses of Network Attached Storage (NAS) servers executing on the cluster nodes. The replication data facility health monitor generates a replication configuration and, upon detection of a failure of the replication data facility at the primary site, uses the replication configuration to automate failover of all of the NAS servers to the destination site.

Abstract: Techniques are described that facilitate predicting and minimizing risks associated with vehicle usage contexts. In one example, a method comprises obtaining, by a system comprising a processor, vehicle state information identifying occupants and objects of a vehicle and relative positions of the occupants and the objects about the vehicle in association with a current usage context of the vehicle. The method further comprises determining, by the system, an assessment of potential injuries associated with the current usage context of the vehicle based on analysis of the vehicle state information, wherein the analysis comprises evaluating potential movement of the occupants and the objects. The method further comprises determining, by the system, risk information regarding a risk associated with the current usage context of the vehicle as a function of the assessment.

Abstract: Techniques for a hub node, provisioned in a site of a hub and spoke overlay network, to receive, store, and/or forward network routing information associated with a spoke, and send packets directly to spoke(s) that are remote from the hub node. A first hub node may receive a network advertisement including a border gateway protocol (BGP) large community string from a first spoke local to the first hub node. The first hub node may send the BGP large community string to a second hub node remote from the first hub node. The second hub node may decode network routing information from the BGP large community string and store the network routing information locally. The second hub node may send a packet from a second spoke local to the second hub node directly to the first spoke without the data packet being routed via the first hub node.

Abstract: Systems, methods, and computer-readable media are disclosed for proactively and adaptively rerouting data to a healthier path through network, as part of flow provisioning, based on environmental variables associated with devices in the network. The present technology includes identifying a routing path for forwarding traffic flows in a network, receiving diagnostic data of a routing device on the routing path. The diagnostic data include one or more environmental parameters associated with internal state and surroundings of the routing device. Further, the present technology includes comparing the diagnostic data of the routing device with a predetermined threshold and modifying, prior to a failure of the routing device, the routing path to bypass the routing device for at least a portion of the traffic flows based on the comparison between the diagnostic data of the routing device and the predetermined threshold.

Abstract: Compounds for treating tuberculosis and, particularly, to anti-tubercular compounds that are 1-(2-(substitutedphenyl)-2-oxoethyl)-3,5-dimethylpyridin-1-ium bromides and their use as anti-tubercular agents.

Abstract: Techniques are described that facilitate intelligent management of adaptable audio-visuals of cloud-based video conferencing sessions. In one example embodiment, method comprises determining, by a system comprising a processor, capabilities of respective devices of participants of a video conferencing session provisioned via a communication network, the capabilities comprising audio-visual capabilities and connection capabilities of the respective devices related to communicating respective data streams of the video conferencing session via the communication network. The method further comprises determining, by the system, respective audio-visual settings of the video conferencing session applicable to the respective devices as a function of the capabilities of the respective devices, and controlling, by the system, performance of the video conferencing session at the respective devices in accordance with the respective audio-visual settings.

Abstract: Detection and transfer of device capabilities between devices of an ecosystem of devices to facilitate improvement of a performance of a defined group task of the ecosystem of devices is presented herein. An ecosystem of devices task improvement system creates the ecosystem of devices comprising respective devices to facilitate sharing respective device capabilities of the respective devices with the ecosystem of devices to increase a performance, via the ecosystem of devices, of the defined group task; in response to determining the defined group task to be performed by the ecosystem of devices, determines the respective device capabilities, and shares a portion of the respective device capabilities that corresponds to a first device of the respective devices with a second device of the respective devices to facilitate increasing the performance of the defined group task.

Abstract: A charging system of a vehicle includes a first conversion device of a first drive system of the vehicle, the first conversion device connected to a first electric motor. The system also includes a second conversion device of a second drive system of the vehicle, the second conversion device connected to a second electric motor. The first drive system and the second drive system are connected to a battery system of the vehicle. The system also includes a switching assembly including a plurality of switches configured to selectively connect the first electric motor and/or the second electric motor to a charge port of the vehicle, and a controller configured to control the switching assembly to define a conversion circuit that includes components of the first drive system and/or the second drive system, and control the conversion circuit to regulate an output voltage and supply power to an energy storage system.

Abstract: Methods, systems, and computer program products for processing cell samples and training machine learning models are disclosed. Some implementations relate to processing disease cell samples to obtain dynamic response data of the cell samples. Some implementations relate to training machine learning models for mapping therapeutics or stimuli to disease outcomes through dynamic response profiles.

Abstract: An improved system and method are disclosed for improving functionality in software applications. In one example, the method includes a computing entity having a network interface, a processor, and a memory configured to store a plurality of instructions. The instructions include instructions for a superblock application having instructions for a function block included therein. The function block is configured to provide functions that are accessible to the superblock application via an application programming interface (API). The functions are provided within the superblock application itself and are accessible within the superblock application without switching context to another application on the computing entity.

Abstract: A method for energy-efficient state change detection and classification of streaming sequential data includes receiving via a first prediction model, sequential data from a sensor. The first prediction model determines a change in an activity state based on the sequential data. An indication that the activity state has changed is transmitted to a second prediction. The second prediction model determines an updated activity state based on the sequential data. The updated activity state is sent to the first prediction model, after which the second prediction enters an inactive state.

Abstract: Antifungal compounds and, particularly, to antifungal compounds that are 4-amino-5-(4-fluoro-3-phenoxyphenyl)-4H-1,2,4-triazole-3-thiol derivatives and their use as antifungal agents.

Abstract: Some embodiments provide a program that retrieves a set of notifications describing failures that occurred on a set of monitored devices. The program further determines a set of topics based on the set of notifications. The program also determines failure modes associated with the set of topic from a plurality of failure modes defined for the set of monitored devices. The program further determines failure modes associated with the set of notifications based on the set of topics and the failure modes associated with the set of topics. The program also receives a particular notification that includes a particular set of words describing a failure that occurred on a particular monitored device in the set of monitored devices. The program further determines a failure mode associated with the particular notification based on the particular set of words and the determined failure modes associated with the set of notifications.