Patents by Inventor Rashmi Rohit Kshirasagar

Rashmi Rohit Kshirasagar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Preventing and Removing Trisulfide Bonds
    Publication number: 20140295495
    Abstract: The present invention pertains to methods of preventing and eliminating trisulfide bonds in proteins such as antibodies. In one embodiment, trisulfide bonds in proteins are converted to disulfide bonds as part of chromatographic purification procedures. In another embodiment, the formation of trisulfide bonds in proteins is inhibited by implementation of methods described herein during the cell culture production of such proteins. In another embodiment, monoclonal antibodies are produced by the methods described herein.
    Type: Application
    Filed: May 11, 2012
    Publication date: October 2, 2014
    Applicant: Biogen Idec MA Inc.
    Inventors: Rashmi Rohit Kshirasagar, Alan Gilbert