Patents by Inventor Rasmus Toft-Kehler

Rasmus Toft-Kehler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATION
    Publication number: 20230190685
    Abstract: The invention relates to formulations comprising a halogenated salicylanilide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin. The formulations may be in the form of a liquid formulation, particularly an aqueous formulation, and provide high concentrations of solubilised halogenated salicylanilide. Also disclosed a formulations in the form of powders and aerosols. Also disclosed are the formulations for use in the treatment of bacterial and viral infections, and the treatment of inflammatory diseases. The formulations are particularly suitable for administration by inhalation for the treatment of bacterial and viral pulmonary infections and the treatment of pulmonary inflammatory diseases.
    Type: Application
    Filed: March 26, 2021
    Publication date: June 22, 2023
    Inventors: Morten SOMMER, Rasmus TOFT-KEHLER, Anne Katrine TOFT-KEHLER, Günter DITZINGER, Mads JELLINGSOE, Philippe ANDRES, Matthias Manne KNOPP
  • TREATMENT
    Publication number: 20230147683
    Abstract: Inhalable compositions comprising niclosamide, or a pharmaceutically acceptable salt thereof, and polyethylene glycol; aerosols of the compositions; and the pulmonary administrations for use in the treatment of viral infections, for example respiratory viral infections.
    Type: Application
    Filed: March 26, 2021
    Publication date: May 11, 2023
    Inventors: Morten SOMMER, Rasmus TOFT-KEHLER, Anne Katrine TOFT-KEHLER, Mads JELLINGSOE, Philippe ANDRES
  • NICLOSAMIDE FORMULATIONS FOR TREATING DISEASE
    Publication number: 20220323384
    Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.
    Type: Application
    Filed: April 18, 2022
    Publication date: October 13, 2022
    Inventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Phillippe Andres, Matthias Knopp
  • Niclosamide formulations for treating disease
    Patent number: 11324708
    Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: May 10, 2022
    Assignee: UNION therapeutics A/S
    Inventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Philippe Andres, Matthias Manne Knopp
  • Combinations comprising dibromopropamidine or diminazene and a tetracycline anti-bacterial agent
    Patent number: 11213533
    Abstract: This invention relates to combination products comprising an amidine selected from dibromopropamidine and diminazene or a pharmaceutically acceptable salt or solvate thereof; and a tetracycline anti-bacterial agent. The combination products are suitable for use in the treatment of bacterial infections or diseases.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: January 4, 2022
    Assignee: UNION Therapeutics A/S
    Inventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler
  • TREATMENT OF INFLAMMATORY CONDITIONS
    Publication number: 20210369650
    Abstract: The invention relates to a halogenated salicylanilide selected from niclosamide and oxyclozanide, or a pharmaceutically acceptable salt or hydrate thereof, for use in topical anti-inflammatory treatment of one or more clinical signs or symptoms of an inflammatory skin condition in a subject, wherein the one or more clinical signs or symptoms are associated with an abnormal inflammatory response, and the topical anti-inflammatory treatment modulates expression in lesional skin of one or more immune effectors selected from proinflammatory mediators and skin barrier molecules.
    Type: Application
    Filed: November 2, 2018
    Publication date: December 2, 2021
    Inventors: Emma GUTTMAN-YASSKY, Morten Otto Alexander SOMMER, Rasmus TOFT-KEHLER, Anne WEISS, Ana Brandusa PAVEL
  • Niclosamide formulations for treating disease
    Patent number: 11045434
    Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: June 29, 2021
    Assignee: UNION therapeutics A/S
    Inventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Philippe Andres, Matthias Manne Knopp
  • COMBINATIONS COMPRISING DIBROMOPROPAMIDINE OR DIMINAZENE AND A TETRACYCLINE ANTI-BACTERIAL AGENT
    Publication number: 20190201422
    Abstract: This invention relates to combination products comprising an amidine selected from dibromopropamidine and diminazene or a pharmaceutically acceptable salt or solvate thereof; and a tetracycline anti-bacterial agent. The combination products are suitable for use in the treatment of bacterial infections or diseases.
    Type: Application
    Filed: September 14, 2017
    Publication date: July 4, 2019
    Inventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler