Patents by Inventor Raul Gil

Raul Gil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oncolytic adenoviruses with mutations in immunodominant adenovirus epitopes and their use in cancer treatment
    Patent number: 11000560
    Abstract: The present invention relates to oncolytic adenoviruses with functional deletions of immunodominant T-cell epitopes of adenovirus proteins, as well as to methods of using the oncolytic adenoviruses for the treatment of diseases, such as cancer. The oncolytic adenoviruses may also contain one or more heterologous nucleic acid sequences each encoding a tumor antigen or epitope. The oncolytic adenoviruses may also contain other mutations and insertions of DNA sequences used to confer selectivity and antitumor potency. The invention has application in the field of cancer therapy.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: May 11, 2021
    Assignee: VCN BIOSCIENCES, S.L.
    Inventors: Ramon Alemany, Raul Gil, Miriam Bazan
  • ONCOLYTIC ADENOVIRUSES WITH MUTATIONS IN IMMUNODOMINANT ADENOVIRUS EPITOPES AND THEIR USE IN CANCER TREATMENT
    Publication number: 20180153946
    Abstract: The present invention relates to oncolytic adenoviruses with functional deletions of immunodominant T-cell epitopes of adenovirus proteins, as well as to methods of using the oncolytic adenoviruses for the treatment of diseases, such as cancer. The oncolytic adenoviruses may also contain one or more heterologous nucleic acid sequences each encoding a tumor antigen or epitope. The oncolytic adenoviruses may also contain other mutations and insertions of DNA sequences used to confer selectivity and antitumor potency. The invention has application in the field of cancer therapy.
    Type: Application
    Filed: May 4, 2016
    Publication date: June 7, 2018
    Inventors: Ramon ALEMANY, Raul GIL, Miriam BAZAN
  • Optical cable with identifiable optical fibers
    Patent number: 8358894
    Abstract: A optical fiber includes an optically transmissive element; at least one curable colored layer surrounding the optically transmissive element; and an additional removable colored layer surrounding and homogeneously covering the curable colored layer. The presence of the additional removable colored layer improves identifiability of the fiber, especially when the latter is included in an optical cable together with other fibers.
    Type: Grant
    Filed: January 7, 2011
    Date of Patent: January 22, 2013
    Assignee: Prysmian S.p.A.
    Inventors: Josep Martin-Regalado, Josep Maria Batlle i Ferrer, Raul Gil, Valentina Ghinaglia
  • OPTICAL CABLE WITH IDENTIFIABLE OPTICAL FIBERS
    Publication number: 20110188041
    Abstract: A optical fiber includes an optically transmissive element; at least one curable colored layer surrounding the optically transmissive element; and an additional removable colored layer surrounding and homogeneously covering the curable colored layer. The presence of the additional removable colored layer improves identifiability of the fiber, especially when the latter is included in an optical cable together with other fibers.
    Type: Application
    Filed: January 7, 2011
    Publication date: August 4, 2011
    Inventors: Josep MARTIN-REGALADO, Josep Maria Batlle i Ferrer, Raul Gil, Valentina Ghinaglia