Patents by Inventor Ravi B. Marala

Ravi B. Marala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of detecting poly(ADP-ribose) polymerase enzymatic activity
    Publication number: 20020142334
    Abstract: The invention provides methods for assaying poly(ADP-ribose) polymerase (PARP) activity and methods for the identification of modulators of PARP activity. These methods comprise contacting immobilized PARP with NAD under conditions that allow PARP auto-ribosylation, contacting the auto-ribosylated PARP with a detectable marker to form a complex and then indirectly or directly measuring the amount of detectable marker bound to the auto-ribosylated PARP, this amount being indicative of PARP activity.
    Type: Application
    Filed: January 18, 2002
    Publication date: October 3, 2002
    Inventors: Janice A. Brown, Ravi B. Marala