Patents by Inventor Ravi Bhasker Patel

Ravi Bhasker Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial membrane nanoparticles as an immunotherapy system for cancer treatment
    Patent number: 11096899
    Abstract: Provided herein are nanoparticles comprising a polyplex core comprising one or more pH-responsive polymers and one or more anionic immune adjuvants, wherein each pH-responsive polymer comprises ionizable amine groups; and a shell of bacterial cell membrane components at least partially coating the polyplex core, wherein the bacterial cell membrane components comprise TLR 2 and/or TLR 4 agonists. Also provided are methods of stimulating an immune response in a mammal using the nanoparticle.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: August 24, 2021
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Shaoqin Gong, Zachary Scott Morris, Mingzhou Ye, Ravi Bhasker Patel, Paul M. Sondel
  • BACTERIAL MEMBRANE NANOPARTICLES AS AN IMMUNOTHERAPY SYSTEM FOR CANCER TREATMENT
    Publication number: 20200078312
    Abstract: Provided herein are nanoparticles comprising a polyplex core comprising one or more pH-responsive polymers and one or more anionic immune adjuvants, wherein each pH-responsive polymer comprises ionizable amine groups; and a shell of bacterial cell membrane components at least partially coating the polyplex core, wherein the bacterial cell membrane components comprise TLR 2 and/or TLR 4 agonists. Also provided are methods of stimulating an immune response in a mammal using the nanoparticle.
    Type: Application
    Filed: September 5, 2019
    Publication date: March 12, 2020
    Inventors: Shaoqin Gong, Zachary Scott Morris, Mingzhou Ye, Ravi Bhasker Patel, Paul M. Sondel