Abstract: Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

Abstract: Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

Abstract: A computer-implemented method includes obtaining road sensor data reflecting speeds of traffic on road segments, transforming the road sensor data using vehicle probe data for the road segments reflecting vehicle speeds, and producing speed estimates for the road segments using the transformed road sensor data. The method can further include determining speeds for road segments between road sensors by smoothing data from sensors near the road segments.

Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of kinesin-like 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding kinesin-like 1. Methods of using these compounds for modulation of kinesin-like 1 expression and for treatment of diseases associated with expression of kinesin-like 1 are provided.

Abstract: Various methods, systems, and computer program products are disclosed for communicating location-based promotional messages to a mobile communication device. The method may include receiving a request associated with a mobile communication device. In response to the request, the method may include determining a location of the mobile communication device and a potential interest of a user of the mobile communication device. Based on the location of the mobile communication device and the potential interest of the user, the method may include identifying a promotional message from among other promotional messages. Upon identification, the method may include communicating the promotional message to be displayed at the mobile communication device.

Abstract: A wearable device in one embodiment includes a motion detection sensor, an alarm clock and a sleep monitor operatively coupled to the motion detection sensor and the alarm clock. The sleep monitor monitors a person during sleep by collecting motion detection sensor data at a first data collection rate and determines a sleep state of the person based on the collected motion detection sensor data at the first data collection rate. If the sleep monitor detects that the alarm clock has entered a snooze mode, then the first data collection rate is increased to a second data collection rate and motion detection sensor data is collected at the second data collection rate while the alarm clock system in the snooze mode.

Abstract: Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

Abstract: Compounds, compositions and methods are provided for modulating the expression of eIF4E-BP1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding eIF4E-BP1. Methods of using these compounds for modulation of eIF4E-BP1 expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E-BP1 are provided.

Abstract: Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

Abstract: Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for content presentation. In one aspect, a method includes receiving a request for an ad to be presented to a user; for a collection of ads, identifying one or more candidate ads including using image keywords derived from images associated with the user to identify the one or more candidate ads; selecting an ad responsive to the ad request from the candidate ads; and sending the selected ad for presentation to the user.

Abstract: In general, one aspect of the subject matter described in this specification can be embodied in methods that include the actions of identifying a target region and an exclusion region of the target region, where the target region encompasses the exclusion region. A target user is identified within the target region and not within the exclusion region encompassed by the target region. A target advertisement is selected for the target user based on the target user being within the target region and not within the exclusion region encompassed by the target region. The target advertisement is sent to the target user. An exclusion user is identified within the exclusion region encompassed by the target region. An exclusion advertisement different from the target advertisement is selected for the exclusion user based on the exclusion user being with the exclusion region. The exclusion advertisement is sent to the exclusion user.

Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of fibroblast growth factor receptor 4 (FGFR4). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding fibroblast growth factor receptor 4. Methods of using these compounds for modulation of fibroblast growth factor receptor 4 expression and for treatment of diseases associated with expression of fibroblast growth factor receptor 4 are provided.

Abstract: Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

Abstract: For separating carbon dioxide (CO2) from a gas stream, a substantially moisture free gas stream is produced using a first temperature swing adsorption (TSA), a first pressure swing adsorption (PSA), a first vacuum swing adsorption (VSA), membrane separation, a first absorption, or any combination thereof. CO2 is captured from the substantially moisture free gas stream and substantially dry CO2 depleted stream is produced using a second TSA, a second PSA, a second VSA, or a second absorption with a non-aqueous solvent with or without a chemical reaction. Adsorbents and/or absorbents used during moisture removal are regenerated using the substantially dry CO2 depleted stream.

Abstract: Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.

Abstract: Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.

Abstract: A computer program product has a computer-readable storage medium having computer program instructions embodied therein for performing a method for implementing a privacy policy for a user. The method may include the user developing rules that determine whether another user (requester) can access information related to the user. The rules may be stored in a database coupled to a server and evaluated when a request is received from the requester to access the information. If a rule is satisfied by the requester, the server can return the information to the requester. The information can be returned at a level of granularity specified by the user in the satisfied rule. A privacy level can be set by the user to allow access to requesters based on the rules or to deny access to any requesters.

Abstract: In a network, a router uses some secret information combined with a cryptographic process in determination of a subnet's routing prefix. Several methods are disclosed, including using an IP suffix for prefix generation and for decryption, maintaining a pool of pseudo prefixes at the router, using public key encryption and symmetric key encryption.

Abstract: Disclosed herein is a method and system for separating carbon dioxide (CO2) from a CO2 containing gas stream containing water vapor and additional impurities, for example, nitrogen, oxygen, sulfur oxides, nitrogen oxides, and mercury. The CO2 is captured by subjecting the CO2 gas feed stream to a temperature swing adsorption step. The temperature swing adsorption step comprises an adsorption step for producing a substantially dry carbon dioxide-depleted stream, and an adsorbent regeneration step comprising heating the adsorbent bed to produce a substantially water vapor-free carbon dioxide stream. Moisture from the gas stream containing CO2 is optionally removed by pressure swing adsorption, temperature swing adsorption, membrane separation, or absorption prior to CO2 capture.