Patents by Inventor Ravi K. Varanasi

Ravi K. Varanasi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10668060
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: June 2, 2020
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Roman V. Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 10646485
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: May 12, 2020
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20190262335
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: May 15, 2019
    Publication date: August 29, 2019
    Inventors: Roman V. Rariy, Alison FLEMING, Jane C. HIRSH, Said SAIM, Ravi K. VARANASI
  • Publication number: 20190255038
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: December 13, 2018
    Publication date: August 22, 2019
    Inventors: Said SAIM, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20190167662
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: June 25, 2018
    Publication date: June 6, 2019
    Inventors: Roman Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 10188644
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: January 29, 2019
    Assignee: COLLEGIUM PHARMACEUTICAL, INC
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20180369236
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 27, 2018
    Inventors: Roman V. Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Publication number: 20180289697
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: April 11, 2018
    Publication date: October 11, 2018
    Inventors: Said SAIM, Alison B Fleming, Ravi K. Varanasi
  • Patent number: 10004729
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: June 26, 2018
    Assignee: COLLEGIUM PHARMACEUTICAL, INC.
    Inventors: Roman V. Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 9968598
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: May 15, 2018
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20170368057
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: July 13, 2017
    Publication date: December 28, 2017
    Inventors: Said SAIM, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20170319575
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: May 26, 2017
    Publication date: November 9, 2017
    Inventors: Roman V. Rariy, Alison FLEMING, Jane C. HIRSH, Said SAIM, Ravi K. VARANASI
  • Patent number: 9737530
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: August 22, 2017
    Assignee: COLLEGIUM PHARMACEUTICAL, INC.
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Patent number: 9682075
    Abstract: Tamper-resistance pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: June 20, 2017
    Assignee: COLLEGIUM PHARMACEUTICAL, INC.
    Inventors: Roman Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 9065741
    Abstract: Methods and apparatuses for identifying and alleviating bottlenecks prior to processing packets in internal feature modules are described. First, a method is provided for aggregating the service policies of various physical interfaces, and using results of the aggregation to determine whether a packet processing engine is capable of satisfying the aggregated service policy information. Second, a method and apparatus for applying the aggregated service policy prior to processing in an internal feature module, such as a crypto-engine. Packets on routers/switches are expected to be subjected to certain policies to address resource contention or streamlining/prioritization on outbound interfaces. Internal bottlenecks that a user can neither see nor control may cause packet transmission guarantees to be violated. Encryption is an example of an internal service that adds overhead thereby creating an internal bottleneck.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: June 23, 2015
    Assignee: Cisco Technology, Inc.
    Inventors: Ravi K. Varanasi, Ravishankar Ganeshithal
  • Publication number: 20150005332
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: July 1, 2014
    Publication date: January 1, 2015
    Inventors: Roman RARIY, Alison FLEMING, Jane C. HIRSH, Said SAIM, Ravi K. VARANASI
  • Publication number: 20150004244
    Abstract: Tamper-resistance pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: June 30, 2014
    Publication date: January 1, 2015
    Inventors: Roman RARIY, Alison Fleming, Jane C. Hirsh, Said SAIM, Ravi K. Varanasi
  • Patent number: 8840928
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: September 23, 2014
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Roman V. Rariy, Alison B. Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 8652443
    Abstract: Described are ethanol-free foamable microemulsions for topical application, and method of making them. The propellants used in the compositions may be environmentally-friendly hydrofluoroalkanes. The foam compositions may also comprise one or more of a variety of active ingredients, including anti-inflammatory agents, anesthetics, and keratolytic agents.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: February 18, 2014
    Assignee: Precision Dermatology, Inc.
    Inventors: Ravi K. Varanasi, Roman V. Rariy
  • Patent number: 8592380
    Abstract: Described herein are emulsions and compositions for the treatment of acne vulgaris. The emulsions may be formulated as aerosol compositions. The aerosol propellant may be a hydrofluoroalkane propellant. The emulsions or compositions may comprise clindamycin phosphate and a buffer salt, and may exhibit decreased rates of clindamycin phosphate hydrolysis. Also described are methods of treating acne vulgaris, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive emulsion or aerosol composition.
    Type: Grant
    Filed: March 22, 2011
    Date of Patent: November 26, 2013
    Assignee: Precision Dermatology, Inc.
    Inventors: Mark W. Trumbore, Wendy Schilling, Ravi K. Varanasi