Abstract: The present disclosure relates to the medical use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions. In particular, the disclosure relates to use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions mediated by mature Nerve Growth Factor (NGF) or its precursor pro-Nerve Growth Factor (pro-NGF).

Abstract: The present disclosure provides methods of treating or preventing respiratory condition and/or for treating an IgE-mediated allergy and/or for reducing an allergic response to an allergen and/or for inducing anergy to an allergen in a subject and/or improving lung function in a subject suffering from an allergy comprising administering to a subject a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.

Abstract: Provided is a system that includes at least one processor programmed or configured to provision a client device for access to an online source of information, transmit a private encryption key of a public/private encryption key pair to a software agent of the client device, receive a first hash value from the software agent, wherein the first hash value is generated using the private encryption key, receive a second hash value from the software agent, determine whether to allow access to the online source of information by the software agent based on the first hash value and the second hash value received from the software agent, process a request to access the online source of information involving the software agent, and store a data record associated with a data transaction involving the online source of information in a data structure. Methods and computer program products are also provided.

Abstract: The present invention relates to medical use of polysulfated polysaccharides and compositions thereof in the treatment of post-operative joint pain in a mammal. In particular, the invention relates to the use of polysulfated polysaccharides and compositions thereof in the treatment of aseptic persistent pain after joint arthroplasty in a mammal.

Abstract: Provided is a system that includes at least one processor programmed or configured to provision a client device for access to an online source of information, transmit a private encryption key of a public/private encryption key pair to a software agent of the client device, receive a first hash value from the software agent, wherein the first hash value is generated using the private encryption key, receive a second hash value from the software agent, determine whether to allow access to the online source of information by the software agent based on the first hash value and the second hash value received from the software agent, process a request to access the online source of information involving the software agent, and store a data record associated with a data transaction involving the online source of information in a data structure. Methods and computer program products are also provided.

Abstract: The present disclosure relates to the medical use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions. In particular, the disclosure relates to use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions mediated by mature Nerve Growth Factor (NGF) or its precursor pro-Nerve Growth Factor (pro-NGF).

Abstract: The present invention relates to the medical use of polysulfated polysaccharides and compositions thereof for the treatment of disease or disorders associated with bone marrow pathologies in the musculoskeletal system of a mammal. In particular, the invention relates to use of polysulfated polysaccharides, such as pentosan polysulfate, in treatment of bone marrow edema lesions or spinal Modic Endplate Changes as assessed by magnetic resonance imaging (MRI).

Abstract: The present invention relates to medical use of polysulfated polysaccharides and compositions thereof in the treatment of post-operative joint pain in a mammal. In particular, the invention relates to the use of the polysulfated polysaccharide, pentosan polysulfate, and compositions thereof in the treatment of aseptic persistent pain after joint arthroplasty in a mammal.

Abstract: Systems and methods for securing user location data are described. A method includes receiving, by a location server computer, an encrypted location from a mobile device. The encrypted location is a location of the mobile device encrypted with a public key. The method then includes receiving, by the location server computer, a location request message from an interaction processing server and partially decrypting, by the location server computer, the encrypted location with a first private key share to form a partially decrypted location. The method further includes transmitting, by the location server computer to the interaction processing server, a location response message with the encrypted location and the partially decrypted location. The interaction processing server then uses the partially decrypted location and the second private key share to form a decrypted location.

Abstract: Methods for the treatment of Acute Respiratory Distress Syndrome (ARDS), particularly ARDS caused by viral infections such as influenza and SARS-CoV-2, comprising the administration of pentosan polysulfate (PPS) are provided. Some provided methods comprise the administration of sodium pentosan polysulfate. Prophylactic methods comprising the administration (for example, intra-nasally) of sodium pentosan polysulfate to inactivate a vims which is causative of ARDS are also provided.

Abstract: The present invention relates to the medical use of polysulfated polysaccharides and compositions thereof for the treatment of disease or disorders associated with bone marrow pathologies in the musculoskeletal system of a mammal. In particular, the invention relates to use of polysulfated polysaccharides, such as pentosan polysulfate, in treatment of bone marrow edema lesions or spinal Modic Endplate Changes as assessed by magnetic resonance imaging (MRI).

Abstract: Embodiments of the disclosure are directed to methods, systems, and devices for the use of portable devices, such as a vehicle driven by a user, that are distinctive physical objects and can be presented to an authentication system for authentication purposes. More specifically, the portable device may be used as a source of information for the authentication system that can be verified. Images may be captured of the portable devices in order to determine their distinctive features for comparison to other physical objects registered to the user. The portable devices may also be a source of metadata, or additional contextual information associated with those portable devices or their interaction with the authentication system. The image data and/or the metadata associated with a portable device can be verified for fraud or risk analysis.

Abstract: Freeze dried active compositions are described. The compositions comprise less than 6.5% by weight water and they may be hydrated or added to end use compositions in order to yield compositions for delivering superior topical benefits to consumers.

Abstract: Disclosed is a method and system for classifying elements of a product. The method comprises identifying elements of the product. Thereupon, features of the one or more elements are determined, using a feature recognition technique. The features correspond to manufacturing operations required for manufacturing the elements, and include sheet metal operations, turn operations, injection moulding operations, and machining operations. The manufacturing operations are determined in a priority order with the sheet metal operation having a highest priority and the machining operation having a least priority.

Abstract: Provided is a system that includes at least one processor programmed or configured to provision a client device for access to an online source of information, transmit a private encryption key of a public/private encryption key pair to a software agent of the client device, receive a first hash value from the software agent, wherein the first hash value is generated using the private encryption key, receive a second hash value from the software agent, determine whether to allow access to the online source of information by the software agent based on the first hash value and the second hash value received from the software agent, process a request to access the online source of information involving the software agent, and store a data record associated with a data transaction involving the online source of information in a data structure. Methods and computer program products are also provided.

Abstract: Systems and methods for securing user location data are described. A method includes receiving, by a location server computer, an encrypted location from a mobile device. The encrypted location is a location of the mobile device encrypted with a public key. The method then includes receiving, by the location server computer, a location request message from an interaction processing server and partially decrypting, by the location server computer, the encrypted location with a first private key share to form a partially decrypted location. The method further includes transmitting, by the location server computer to the interaction processing server, a location response message with the encrypted location and the partially decrypted location. The interaction processing server then uses the partially decrypted location and the second private key share to form a decrypted location.

Abstract: The present disclosure relates to the medical use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions. In particular, the disclosure relates to use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions mediated by mature Nerve Growth Factor (NGF) or its precursor pro-Nerve Growth Factor (pro-NGF).

Abstract: This application provides methods for treating a human subject suffering from a bone fracture by administering to the subject a population of cells enriched from STRO-1+ multipotential cells and/or multipotential progeny of such cells.

Abstract: Systems and methods for securing user location data are described. A method includes receiving, by a location server computer, an encrypted location from a mobile device. The encrypted location is a location of the mobile device encrypted with a public key. The method then includes receiving, by the location server computer, a location request message from an interaction processing server and partially decrypting, by the location server computer, the encrypted location with a first private key share to form a partially decrypted location. The method further includes transmitting, by the location server computer to the interaction processing server, a location response message with the encrypted location and the partially decrypted location. The interaction processing server then uses the partially decrypted location and the second private key share to form a decrypted location.

Abstract: A method for detecting fraudulent activity includes: generating a fraud control rule associated with a payment account parameter of a payment account; receiving a request message from a user device, where the request message includes social media data associated with a social media account of a user, where the social media data includes unencrypted social media data and encrypted social media data; analyzing the request message for fraudulent activity by analyzing the social media data with respect to the fraud control rule; automatically generating a response message including at least one of: a processing request message associated with the request message in response to the social media data not satisfying the fraud control rule; and a rejection message in response to the social media data satisfying the fraud control rule; and communicating the response message.