Patents by Inventor Ravi Sankar Loka

Ravi Sankar Loka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HEPARANASE INHIBITORS FOR TREATMENT OF DIABETES
    Publication number: 20230102826
    Abstract: Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Application
    Filed: December 2, 2022
    Publication date: March 30, 2023
    Applicant: Wayne State University
    Inventors: Hien M. Nguyen, Kezhong Zhang, Ravi Sankar Loka
  • Heparanase inhibitors for treatment of diabetes
    Patent number: 11524026
    Abstract: Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: December 13, 2022
    Assignee: Wayne State University
    Inventors: Hien M. Nguyen, Kezhong Zhang, Ravi Sankar Loka
  • HEPARANASE INHIBITORS AND THEIR USE AS ANTI-CANCER COMPOUNDS
    Publication number: 20210330693
    Abstract: Anti-heparanase compounds for the treatment of cancer are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Application
    Filed: December 5, 2019
    Publication date: October 28, 2021
    Applicants: Wayne State University, Technion, Israel Institute of Technology, University of Iowa Research Foundation
    Inventors: Hien M. Nguyen, Ravi Sankar Loka, Eric Sletten, Israel Vlodavsky
  • HEPARANASE INHIBITORS FOR TREATMENT OF DIABETES
    Publication number: 20210205350
    Abstract: Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Application
    Filed: December 9, 2020
    Publication date: July 8, 2021
    Applicant: Wayne State University
    Inventors: Hien M. Nguyen, Kezhong Zhang, Ravi Sankar Loka