Patents by Inventor Ravi Thadhani

Ravi Thadhani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEVICES, ASSAYS AND METHODS OF TESTING PREECLAMPSIA
    Publication number: 20230184785
    Abstract: Devices based on semi-quantitative “sandwich” lateral flow immunoassay and methods of using the devices are provided to determine the presence and estimate the quantity of Flt-1 protein found in the plasma, serum, whole blood, saliva, urine or another bodily fluid of pregnant women in order to predict or screen for the risk of preeclampsia in pregnant women. Assays based on the devices are also provided.
    Type: Application
    Filed: May 18, 2021
    Publication date: June 15, 2023
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: S. Ananth Karumanchi, Anders H. Berg, Ravi Thadhani
  • Diagnostic and therapeutic uses of gelsolin in renal failure
    Patent number: 10272136
    Abstract: The invention is directed, in part, to the use of gelsolin to diagnose, monitor, and treat subjects with renal failure (e.g., chronic renal failure subjects on dialysis).
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: April 30, 2019
    Assignees: The General Hospital Corporation, The Brigham and Women's Hospital, Inc., Beth Israel Deaconess Medical Center, Inc.
    Inventors: Ravi Thadhani, Thomas P. Stossel, Po-Shun Lee, Ananth Karumanchi
  • DIAGNOSTIC AND THERAPEUTIC USES OF GELSOLIN IN RENAL FAILURE
    Publication number: 20170189483
    Abstract: The invention is directed, in part, to the use of gelsolin to diagnose, monitor, and treat subjects with renal failure (e.g., chronic renal failure subjects on dialysis).
    Type: Application
    Filed: January 17, 2017
    Publication date: July 6, 2017
    Inventors: RAVI THADHANI, THOMAS P. STOSSEL, PO-SHUN LEE, ANANTH KARUMANCHI
  • Assays and methods of treatment relating to vitamin D insufficiency
    Patent number: 9671414
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: June 6, 2017
    Assignees: Beth Israel Deaconess Medical Center, Inc., The General Hospital Corporation
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • Assays and methods of treatment relating to vitamin D insufficiency
    Patent number: 9606131
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: March 28, 2017
    Assignees: The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • Diagnostic and therapeutic uses of gelsolin in renal failure
    Patent number: 9575072
    Abstract: The invention is directed, in part, to the use of gelsolin to diagnose, monitor, and treat subjects with renal failure (e.g., chronic renal failure subjects on dialysis).
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: February 21, 2017
    Assignees: The Brigham and Women's Hospital, Inc., Beth Israel Deaconess Medical Center, Inc., The General Hospital Corporation
    Inventors: Ravi Thadhani, Thomas P. Stossel, Po-Shun Lee, Ananth Karumanchi
  • Assays and methods of treatment relating to vitamin D insufficiency
    Patent number: 9329190
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: May 3, 2016
    Assignees: The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • ASSAYS AND METHODS OF TREATMENT RELATING TO VITAMIN D INSUFFICIENCY
    Publication number: 20160077115
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Application
    Filed: May 2, 2014
    Publication date: March 17, 2016
    Applicant: The General Hospital Corporation
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • Assays and methods of treatment relating to vitamin D insufficiency
    Patent number: 9217748
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: December 22, 2015
    Assignees: The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • ASSAYS AND METHODS OF TREATMENT RELATING TO VITAMIN D INSUFFICIENCY
    Publication number: 20150247872
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Application
    Filed: May 11, 2015
    Publication date: September 3, 2015
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • Assays and methods of treatment relating to vitamin D insufficiency
    Patent number: 9052308
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: June 9, 2015
    Assignees: The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • ASSAYS AND METHODS OF TREATMENT RELATING TO VITAMIN D INSUFFICIENCY
    Publication number: 20140113885
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Application
    Filed: January 6, 2012
    Publication date: April 24, 2014
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • ASSAYS AND METHODS OF TREATMENT RELATING TO VITAMIN D INSUFFICIENCY
    Publication number: 20130324505
    Abstract: Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
    Type: Application
    Filed: June 14, 2013
    Publication date: December 5, 2013
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Anders Hayden Berg, Ishir Bhan
  • OPTIMIZING ERYTHROPOIETIN THERAPY
    Publication number: 20120020974
    Abstract: The methods described herein can be used to identify ex ante which hemodialysis patients are likely to develop EPO resistance and therefore will require additional rHu EPO, and to provide treatments that can reduce the need for additional rHu EPO. In addition, the methods can be used to predict which subjects have a higher risk of mortality, to identify high-risk patients who can then be monitored more closely or treated more aggressively. Also provided are kits for carrying out the described methods.
    Type: Application
    Filed: October 16, 2009
    Publication date: January 26, 2012
    Applicants: BETH ISRAEL DEACONESS MEDICAL CENTER, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Ravi Thadhani, S. Ananth Karumanchi, Eliyahu Khankin, Walter P. Mutter
  • DIAGNOSTIC AND THERAPEUTIC USES OF GELSOLIN IN RENAL FAILURE
    Publication number: 20090258830
    Abstract: The invention is directed, in part, to the use of gelsolin to diagnose, monitor, and treat subjects with renal failure (e.g., chronic renal failure subjects on dialysis).
    Type: Application
    Filed: January 23, 2009
    Publication date: October 15, 2009
    Inventors: Ravi Thadhani, Thomas P. Stossel, Po-Shun Lee, Ananth Karumanchi
  • PREDICTING DIABETIC NEPHROPATHY
    Publication number: 20080113386
    Abstract: The invention relates to methods and compositions for identifying subjects who are predisposed to having diabetic nephropathy (DN).
    Type: Application
    Filed: January 24, 2008
    Publication date: May 15, 2008
    Applicant: The General Hospital Corporation
    Inventors: Ravi Thadhani, S. Karumanchi, Towia Libermann
  • Predicting diabetic nephropathy
    Publication number: 20070111245
    Abstract: The invention relates to methods and compositions for identifying subjects who are predisposed to having diabetic nephropathy (DN).
    Type: Application
    Filed: November 9, 2006
    Publication date: May 17, 2007
    Inventors: Ravi Thadhani, S. Karumanchi, Towia Libermann
  • Screening for gestational disorders
    Publication number: 20050148023
    Abstract: The invention relates to methods and compositions for identifying pregnant subjects having, or predisposed to having, gestational diabetes, preeclampsia, and gestational hypertension. The methods are applicable to urine and/or blood samples and can be conducted prior to the third trimester of pregnancy, and as early as the first trimester.
    Type: Application
    Filed: August 16, 2004
    Publication date: July 7, 2005
    Inventors: Ravi Thadhani, Myles Wolf, Tanya Knickerbocker, Gavin MacBeath
  • Screening for gestational disorders
    Publication number: 20050148040
    Abstract: The invention relates to methods and compositions for identifying subjects having, or predisposed to having, gestational diabetes, preeclampsia, and gestational hypertension. The methods are applicable to urine and/or blood samples and can be conducted prior to the third trimester of pregnancy.
    Type: Application
    Filed: September 23, 2004
    Publication date: July 7, 2005
    Inventors: Ravi Thadhani, S. Karumanchi