Patents by Inventor Ravinder Jolly

Ravinder Jolly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of bipyridine compound 'Caerulomycin A' derivatives and analogs thereof as immunosuppressive agents
    Publication number: 20070078167
    Abstract: The present invention relates to an isolated bioactive molecule Caerulomycin A, derivatives and analogs thereof as effective immunosuppressive agents. The immunosuppressive property of the compound is targeted in particular against the lymphocytes, CD4+ T cells, CD8+ T cells and B cells and in the production of IL-4 and IFN-? and antibodies. The compound operates through a mechanism by downregulating the expression of activation marker CD28 and upregulating the immunosuppressive marker CTLA-4. Caerulomycin A has previously been isolated from Streptomyces caeruleus and found to have useful antifungal activity. Prior to the present invention however, this compound had not been determined to have immunomodulatory activity.
    Type: Application
    Filed: September 12, 2006
    Publication date: April 5, 2007
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Arvind Singla, Javed Agrewala, Rakesh Vohra, Ravinder Jolly