Patents by Inventor Ravindra Babu Bollu

Ravindra Babu Bollu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PROCESSES FOR PREPARATION OF TEZACAFTOR
    Publication number: 20230057246
    Abstract: The present invention generally relates to processes for preparation of Tezacaftor and pharmaceutical composition comprising the same. The present invention also encompasses novel intermediates of tezacaftor, processes for its preparation and use of said intermediates in the preparation of tezacaftor.
    Type: Application
    Filed: February 5, 2021
    Publication date: February 23, 2023
    Inventors: Ravindra Babu Bollu, Venkateswar Rao Challagonda, Prasanta Dalasingh, Ananth Reddy Manda, Srikanth Konda, Narender Satu, Uma Maheswer Rao Vasireddi
  • PROCESS AND POLYMORPHIC FORMS OF BICTEGRAVIR AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS OR CO-CRYSTALS THEREOF
    Publication number: 20220306650
    Abstract: The present invention generally relates to polymorphic forms of bictegravir, its salts, co-crystals, solvates or hydrates thereof and process for the preparation of the same and also relates to pharmaceutical compositions containing the same. The present invention also relates to a process for preparation of bictegravir substantially free from its diastereomer impurity.
    Type: Application
    Filed: June 18, 2020
    Publication date: September 29, 2022
    Inventors: Ram Thaimattam, Sureshbabu Radhakrishnan, Pavan Kumar Seethamraju, Satheesh Beeravalli, Uma Maheswara Rao Pampana, Anil Kumar Reddy Shamakura, Ravindra Babu Bollu, Uma Maheswer Rao Vasireddi
  • Process and crystalline forms of lumacaftor
    Patent number: 11345685
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Process and crystalline forms of Lumacaftor
    Patent number: 11345684
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Stable amorphous form of sacubitril valsartan trisodium complex and processes for preparation thereof
    Patent number: 11318116
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: May 3, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • Process for the preparation and particle size reduction of pirfenidone
    Patent number: 11066368
    Abstract: The present invention relates to an improved process for the preparation of pure pirfenidone having a particular particle size distribution, a crystalline form of pirfenidone, and pharmaceutical compositions thereof, as well as methods for particle size reduction of pirfenidone, and methods for particle size reduction of pirfenidone by wet milling techniques using colloid mill, ultrasonicator, or high speed homogenizer devices.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: July 20, 2021
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Venkata Pramod Kumar Mandadapu, Venkata Sunil Kumar Indukuri, Satyanarayana Chava, Tirumala Rao Galla, Jagadeeswara Rao Dadi, Uma Maheswer Rao Vasireddi
  • Process for 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline
    Patent number: 11053220
    Abstract: The present invention relates to an improved process for the preparation of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline of Formula (I).
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: July 6, 2021
    Assignee: LAURUS LABS LTD
    Inventors: Ravindra Babu Bollu, Veera Narayana Bandlamudi, Vivek Kumar Kudirilla, Rambabu Vemula, Uma Maheswer Rao Vasireddi
  • PROCESS AND CRYSTALLINE FORMS OF LUMACAFTOR
    Publication number: 20210061792
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Application
    Filed: October 9, 2020
    Publication date: March 4, 2021
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • PROCESS AND CRYSTALLINE FORMS OF LUMACAFTOR
    Publication number: 20210053949
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 25, 2021
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • STABLE AMORPHOUS FORM OF SACUBITRIL VALSARTAN TRISODIUM COMPLEX AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20210046050
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Application
    Filed: September 22, 2020
    Publication date: February 18, 2021
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • Stable amorphous form of sacubitril valsartan trisodium complex and processes for preparation thereof
    Patent number: 10857132
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: December 8, 2020
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • AN IMPROVED PROCESS FOR 3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL) ANILINE
    Publication number: 20200377475
    Abstract: The present invention relates to an improved process for the preparation of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline of Formula (I).
    Type: Application
    Filed: December 28, 2018
    Publication date: December 3, 2020
    Inventors: Ravindra Babu Bollu, Veera Narayana Bandlamudi, Vivek Kumar Kudirilla, Rambabu Vemula Hyderabad, Uma Maheswer Rao Vasireddi
  • Process and crystalline forms of lumacaftor
    Patent number: 10844048
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: January 6, 2018
    Date of Patent: November 24, 2020
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • PROCESS AND CRYSTALLINE FORMS OF LUMACAFTOR
    Publication number: 20190375734
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Application
    Filed: January 6, 2018
    Publication date: December 12, 2019
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • STABLE AMORPHOUS FORM OF SACUBITRIL VALSARTAN TRISODIUM COMPLEX AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20190282546
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Application
    Filed: October 10, 2017
    Publication date: September 19, 2019
    Applicant: Laurus Labs Ltd.
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Challagonda Rao Venkateswar, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • Process for preparing eptifibatide
    Patent number: 9850285
    Abstract: The present invention provides processes for preparation of eptifibatide that involve coupling of amino acids in a (2+5), (4+3) and (3+4) sequence method. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: December 26, 2017
    Assignee: LAURUS LABS LIMITED
    Inventors: Subha Nair Velayudhan, Ravindra Babu Bollu, Venkata S. Indukuri, Seeta R. Gorantla, Venkata S. Kallam, Bala M. Madivada
  • Process for preparing eptifibatide
    Patent number: 9156885
    Abstract: The present invention provides processes for preparation of eptifibatide that involve coupling of amino acids in a (2+5), (4+3) and (3+4) sequence method. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: October 13, 2015
    Assignee: Laurus Labs Private Ltd.
    Inventors: Subha Nair Velayudhan, Ravindra Babu Bollu, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Venkata Siva RamaKrishna Reddy Kallam, Bala Muralikrishna Madivada
  • Efficient process to induce enantioselectivity in procarbonyl compounds
    Patent number: 9073817
    Abstract: The present invention provides an efficient method to induce the enantioselectivity in procarbonyl compounds using chiral organometallic complexes. The present invention also provides a method for producing chiral organometallic complexes using a chiral additive, achiral additive, a base and a metal salt.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: July 7, 2015
    Assignee: Laurus Labs Private Limited
    Inventors: Ravindra Babu Bollu, Narasimha Rao Ketavarapu, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Satyanarayana Chava
  • Phosphodiesterase inhibitors
    Patent number: 8338431
    Abstract: The present invention relates to a compound according to formula I, wherein X, A, G, E, R1, R2, R3 are as shown herein; and pharmaceutically acceptable salts, hydrates, N-oxides or solvates hereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: December 25, 2012
    Assignee: Leo Pharma A/S
    Inventors: Ravindra Babu Bollu, Jakob Felding, Simon Feldbæk Nielsen, Jens Christian Højland Larsen
  • EFFICIENT PROCESS TO INDUCE ENANTIOSELECTIVITY IN PROCARBONYL COMPOUNDS
    Publication number: 20120264933
    Abstract: The present invention provides an efficient method to induce the enantioselectivity in procarbonyl compounds using chiral organometallic complexes. The present invention also provides a method for producing chiral organometallic complexes using a chiral additive, achiral additive, a base and a metal salt.
    Type: Application
    Filed: June 22, 2012
    Publication date: October 18, 2012
    Applicant: Laurus Labs Private Limited
    Inventors: Ravindra Babu BOLLU, Narasimha Rao Ketavarapu, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Satyanarayana Chava