Patents by Inventor Ravindra Guthikonda

Ravindra Guthikonda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted sulfonamides
    Publication number: 20070105914
    Abstract: The substituted sulfonamides of the invention are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.
    Type: Application
    Filed: September 14, 2004
    Publication date: May 10, 2007
    Inventors: Helen Armstrong, Linda Chang, Ravindra Guthikonda, William Hagmann, Linus Lin, Shrenik Shah
  • Substituted amides
    Publication number: 20050234061
    Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.
    Type: Application
    Filed: April 19, 2005
    Publication date: October 20, 2005
    Inventors: William Hagmann, Linus Lin, Shrenik Shah, Ravindra Guthikonda, Hongbo Qi, Linda Chang, Ping Liu, Helen Armstrong, James Jewell, Thomas Lanza
  • Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
    Patent number: 5972975
    Abstract: Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: October 26, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Craig Esser, William Hagmann, William Hoffman, Shrenik Shah, Kenny Wong, Renee Chabin, Ravindra Guthikonda, Malcolm Maccoss, Charles Caldwell, Philippe Durette
  • Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
    Patent number: 5908842
    Abstract: Substituted 2-acylaminopyridine compounds and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders.
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: June 1, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Ravindra Guthikonda, William Hagmann, Malcolm Maccoss, Shrenik Shah, Philippe Durette
  • 1-Carba-6-(1-hydroxyethyl)-2-carbonyl-penem-3-carboxylic acid and preparation thereof
    Patent number: 4321197
    Abstract: Antibiotic 1-carba-6-(1-hydroxyethyl-2-carbonyl-penem-3-carboxylic acid is prepared by total chemical synthesis from 4-iodomethyl-1-(t-butyldimethylsilyl)-2-azetidinone.
    Type: Grant
    Filed: December 24, 1980
    Date of Patent: March 23, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Lovji D. Cama, Ravindra Guthikonda, Burton G. Christensen