Patents by Inventor Rawle Hollingsworth

Rawle Hollingsworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7579343
    Abstract: 1H-Pyrrolo-1,4-thiazines and a process for the preparation thereof are described. These compounds are useful as enzyme inhibitors in cells, particularly for medical uses.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: August 25, 2009
    Assignee: Board of Trustees of Michigan State University
    Inventors: Rawle Hollingsworth, Li Gao
  • Publication number: 20070265451
    Abstract: A process for preparing N-(substituted)-C-(substituted methyl)-oxazolidinones, C-(substituted methyl)-oxazolidinones, and N-(substituted)-C-(substituted methyl)-oxazolidinones, preferably chiral, from optically active C-(protected oxymethyl)-oxazolidinones is described. The process can be used to produce combinatorial libraries of the above substituted oxazolidinones in a two or three step reaction comprising a plurality of reagents differing in numbers of carbons or particular substituted oxazolidinones. A number of substituted oxazolidinones produced using the above process have been discovered to have antimicrobial activity.
    Type: Application
    Filed: June 11, 2007
    Publication date: November 15, 2007
    Applicant: Board of Trustees of Michigan State University
    Inventors: Rawle Hollingsworth, Guijun Wang, Raghavakaimal Padmakumar, Jianmin Mao, Huiping Zhang, Zongmin Dai, Kanakamma Puthuparampil
  • Publication number: 20070055062
    Abstract: 1H-Pyrrolo-1,4-thiazines and a process for the preparation thereof are described. These compounds are useful as enzyme inhibitors in cells, particularly for medical uses.
    Type: Application
    Filed: September 6, 2006
    Publication date: March 8, 2007
    Applicant: Board of Trustees of Michigan State University
    Inventors: Rawle Hollingsworth, Li Gao
  • Publication number: 20060106212
    Abstract: A process for producing 2-thiaquiolizidines which are glycosidase and glycosyltransferase inhibitors is described. The compounds are of the formula: where x is 0 to 3.
    Type: Application
    Filed: November 15, 2004
    Publication date: May 18, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Rawle Hollingsworth, Li Gao
  • Publication number: 20060100423
    Abstract: A process for the preparation and separation of the pentoses, xylose and arabinose from mixtures of saccharides by forming acetals is described. D-xylose is a precursor to xylitol, a sweetener, and L-arabinose is a precursor to the drug intermediate (R)-3,4-dihydroxybutyric acid, carnitine and agrichemicals.
    Type: Application
    Filed: November 9, 2004
    Publication date: May 11, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventor: Rawle Hollingsworth
  • Publication number: 20050209430
    Abstract: Polyether polymers providing a backbone substituted at intervals with electron stabilizing groups containing electron withdrawing groups are described. The polymers capture electrons and are electronegative. The polymers act to solvate alkali metals so that electrons are withdrawn from the alkali metal into the polymer. The polymer compositions are conductive under certain conditions and are magnetic. The compositions are useful in electronic applications.
    Type: Application
    Filed: March 17, 2004
    Publication date: September 22, 2005
    Applicant: Board of Trustees Michigan State University
    Inventors: Rawle Hollingsworth, Yuqing Chen