Abstract: A device for treating a tissue opening includes a proximal portion including an elongated flexible member, a capsule releasably coupled to a distal end of the flexible member and including a lumen extending therethrough and a clip including a pair of arms movably housed within the capsule. A suture extending along a first one of the pair of arms and including a loop at a distal end thereof extending across an opening extending through the first one of the pair of arms. A suture grabbing element extending laterally from a second one of the pair of arms and including a hook so that, when the pair of arms are moved toward a closed configuration, the hook extends through the opening to grab the loop and draw the distal end of the suture from the first one of the pair of arms toward the second one of the pair of arms.

Abstract: Control methods are disclosed for continuous, unmodulated, multiple catalytic conversion step processes using at least two catalysts, a first catalyst and a second catalyst, that accommodate changes in the performance of each catalyst and the relative performances of the catalysts. In the methods, certain process parameters are used in a manner that is indicative of changes in catalyst performance, and the control methods provide for adjustment of at least one of: the absolute amount of catalytically active species and relative amounts of each of the first catalyst and second catalyst and at least one of the rate of feed or concentration of the raw material to the reaction zone.

Abstract: A string trimmer lighting system includes a string trimmer having a motor, a handle, an elongated shaft, a debris shield, and a trimmer head; and a lighting device having a light source enclosed within a housing, an elongated member, a clamp, and one or more enclosure fasteners; wherein the housing includes a lens, a power switch, and a power source; wherein the light source emits light through the lens; wherein the elongated member removably attaches the housing to the clamp; wherein the clamp removably receives the elongated shaft; wherein the one or more enclosure fasteners removably tighten the clamp around the elongated shaft.

Abstract: An industrial control system includes an encryption device, a decryption device and a mission-critical communication link connecting the encryption device to the decryption device. The encryption device is configured to send encrypted messages to the decryption device over the mission-critical communication link. The system includes a failure monitor configured to monitor for a failure of the encryption device or the decryption device, and, in the event of failure, to continue the sending of the messages to the decryption device but without encrypting the messages.

Abstract: An industrial control system includes an encryption device, a decryption device and a mission-critical communication link connecting the encryption device to the decryption device. The encryption device is configured to send encrypted messages to the decryption device over the mission-critical communication link. The system includes a failure monitor configured to monitor for a failure of the encryption device or the decryption device, and, in the event of failure, to continue the sending of the messages to the decryption device but without encrypting the messages.

Abstract: A communication system includes an encryption device, a decryption device and a communication link connecting the encryption device to the decryption device. The encryption device is configured to send encrypted messages to the decryption device over the communication link. The system includes a failure monitor configured to monitor for a failure of the encryption device or the decryption device, and, in the event of failure, to continue the sending of the messages to the decryption device but without encrypting the messages.

Abstract: The present disclosure provides boron-containing diacylhydrazines having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein A, R4, and R5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems. Thus, the present disclosure is useful for applications such as gene therapy, treatment of disease, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable.

Abstract: A communication system includes an encryption device, a decryption device and a communication link connecting the encryption device to the decryption device. The encryption device is configured to send encrypted messages to the decryption device over the communication link. The system includes a failure monitor configured to monitor for a failure of the encryption device or the decryption device, and, in the event of failure, to continue the sending of the messages to the decryption device but without encrypting the messages.

Abstract: The present disclosure provides boron-containing diacylhydrazines having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein A, R4, and R5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems. Thus, the present disclosure is useful for applications such as gene therapy, treatment of disease, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable.

Abstract: The present disclosure provides boron-containing diacylhydrazines having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein A, R4, and R5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems. Thus, the present disclosure is useful for applications such as gene therapy, treatment of disease, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable.

Abstract: The present disclosure provides boron-containing diacylhydrazines having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein A, R4, and R5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems. Thus, the present disclosure is useful for applications such as gene therapy, treatment of disease, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable.

Abstract: A safety assembly for preventing a swing from twisting includes a frame coupled to a swing set frame. The frame may support the swing. A retainer is coupled between the frame and the swing set frame. The frame is retained on the swing set frame. A stabilizing arm is coupled to the frame. The stabilizing arm prevents the frame from rotating.

Abstract: Compounds of the formula are disclosed. The compounds are CCR1 antagonists which are useful for the treatment and prevention of inflammatory and autoimmune diseases. Other embodiments are also disclosed.

Abstract: A method of distributing content over multiple social media networks and providing analysis based thereon is disclosed herein. Additionally, an apparatus for carrying out the method are disclosed. In one embodiment the apparatus includes: (1) a content publisher configured to automatically distribute content over multiple social media networks according to a delivery schedule; and (2) an action analyzer configured to monitor, on at least one of the social media networks, reaction to the content that has been distributed and generate a stimulus report based on the reaction according to a selectable format.

Abstract: Methods and apparatus for powering a dimmable ballast operating a gas-discharge bulb in a cold cathode mode of operation, that is, without requiring heating of filaments. The ballast circuit includes a rectifier, bypass capacitor, driver circuit, and a tank circuit that includes a resonant circuit that are configured to ionize a light source, such as a fluorescent lamp, every half cycle of the input voltage. The bypass capacitor supplies energy to produce a high frequency current introduced into the resonant circuit to continually recycle energy in the resonant circuit, resulting in a ballast with a high power factor. A tank circuit comprising a tapped inductor operating in a non-saturated or limited saturated mode provides additional voltage to the bulb to ionize the bulb. The ballast may be dimmed and combined with other energy savings circuitry.

Abstract: Automated control systems and methods for lighting systems are described herein. In certain embodiments, the control systems include either an improved dimmable ballast, an improved dimmer circuit, or both. The control systems are suitable for various applications including a light harvesting system and a security lighting system.

Abstract: Methods and apparatus for powering a dimmable ballast operating with LED light source(s) are provided. In one embodiment, the ballast circuit includes sections comprising: power input, full wave bridge rectifier, voltage regulator, integrated circuit driver, switching transistors, bypass capacitor, resonant circuit, rectifier diodes, and an LED light source. The resonant circuit receives energy from the voltage source and the bypass capacitor every switching cycle, and provides current to the rectifier diodes and one or more LEDs for generating light. Further, because the current flowing into the resonant circuit is substantially sinusoidal and in line with the input voltage, the circuit exhibits a desirable power factor. The ballast circuit can also effectively dimmed over a wide range using a phase angle dimmer, allowing further energy savings.

Abstract: Methods and apparatus for dimming light sources are described herein. In certain embodiments, a bias circuit selectively biases a solid state switch during a portion of half-cycle of a line voltage after a settable delay. In some embodiments, the delay of the bias circuit is adjustable by a user, which varies the amount of energy provided to a light source, and the light generated there from. A charge circuit biases the switch for a period of time in the event the bias circuit experiences an operating condition (a ringing current) that may cause the switch to become open during the half-cycle of the line current. As a result of the charge circuit, the light source coupled to the line current does not experience substantial flickering and is compatible with low power compact fluorescent lights. The dimmer can be combined with other components to form a light harvesting system.

Abstract: Methods and apparatus for powering a ballast that is dimmable and has a high power factor. The ballast circuit includes a rectifier, bypass capacitor, a driver circuit, and a resonant circuit that are configured to actuate a light source, such as a fluorescent lamp. Specifically, the bypass capacitor stores energy to produce a high frequency current which is introduced into the resonant circuit to continually recycle energy in the resonant circuit, resulting in a circuit with a high power factor. Further, because the current flowing into the resonant circuit is substantially sinusoidal, the circuit generally has an ideal crest factor, thereby increasing the lifespan of the light source.

Abstract: Methods and apparatus for saving energy in a ballast comprising a tank circuit for a gas-discharge lamp are disclosed. A feedback circuit and a filament shutoff circuit cooperate to detect energy in the tank ballast and save energy during operation. The feedback circuit detects current flowing in the tank circuit of a ballast and can signal to shut off a voltage regulator in the ballast, and/or signal to a filament shut off circuit to reduce energy consumed by the filaments in the bulb after ionization has occurred. A time delay ensures that the signal voltage generated does not immediately deactivate the voltage regulator and/or the filament shutoff circuit when powering the ballast, but only does so after ionization has occurred. In this manner, energy consumption is reduced after ionization of the bulbs has occurred.