Patents by Inventor Raymond Beckett

Raymond Beckett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090069322
    Abstract: Compounds of formula (I) are antibacterial or antiprotozoal agents for treatment of infections in humans and non-human mammals, wherein: Z represents a radical of formula —N(OH)CH(?O) or formula C(?O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or except when Z is a radical of formula —N(OH)CH(?O), a hydroxy, halo or amino group; R2 represents a group R10—(X)n-(ALK)m— wherein R10, ALK, X, m and n are as defined in the specification; R3 represents hydrogen, (C1-C6) alkyl or phenyl(C1-C6)alkyl-; and R5 and R6 are as defined in the specification.
    Type: Application
    Filed: September 26, 2006
    Publication date: March 12, 2009
    Applicant: British Biotech Pharmaceuticals Ltd.
    Inventors: Paul Raymond Beckett, Steven Launchbury, Gilles Pain, Lisa Marie Pratt
  • Patent number: 7323596
    Abstract: Compounds of formula (I) and (IA) have antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH(?O) or of formula C(?O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of formula N(OH)CH(?O), a hydroxy or amino group; R2 represents a radical of formula R10—(X)n-(ALK)m- wherein R10 represents hydrogen, or an optionally substituted c1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, ALK represents a straight or branched divalent C1-C6 alkylene, C2-C6 ?alkenylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent NH—, —O— or S— linkages, X represents NH—, —O— or S—, and m and n are independently 0 or 1; R3 represents hydrogen, C1-C6alkyl, or benzyl; and R4 is as defined in the specification.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: January 29, 2008
    Assignee: De Novo Pharmaceuticals Ltd.
    Inventors: Barry Porter, Paul Gane, Raymond Beckett, Kenneth Keavey, Jac Wijkmans, Lydia Saroglou
  • Patent number: 7323563
    Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: January 29, 2008
    Assignee: British Biotech Pharmaceuticals Ltd.
    Inventors: Michael George Hunter, Paul Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Marie Spavold
  • Publication number: 20070129310
    Abstract: Compounds of formula (II) have antibacterial activity: wherein: Q represents a radical of formula —N(OH)CH(?0) or formula —C(?O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl or, except when Q is a radical of formula —N(OH)CH(?0), a hydroxy, halo or amino group; R2 represents a group R10—(D)n—(ALK)m— wherein R10 represents hydrogen or an optionally substituted C-C6 alkyl, C2-C6 alkynyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group and ALK represents a straight or branched divalent C-C6 alkylene, C2-C6 alkynylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent —NH—, —O—or -Slinkages, D represents —NH—, —O—or —S—, and m and n are independently 0 or 1; R4 represents the side chain of a natural or non-natural alpha amino acid; ring A represents an optionally substituted monocyclic heterocyclic ring containing from 5 to 7 ring atoms, one of which is the nitrogen atom shown, the remaining ring atoms being selected from compatible combinations of carbon, oxygen,
    Type: Application
    Filed: December 2, 2002
    Publication date: June 7, 2007
    Applicant: VERNALIS (OXFORD) LTD.
    Inventors: Raymond Beckett, Jac Wijkmans, Thomas Krulle
  • Patent number: 7173053
    Abstract: Compounds of formula (I) are antibacterial or antiprotozoal agents for treatment of infections in humans and non-human mammals, wherein: Z represents a radical of formula —N(OH)CH(?O) or formula C(?O)NH(OH); R1 represents hydrogen, methyl or trifluromethyl, or except when Z is a radical of formula —N(OH)(?O), a hydroxy, halo or amino group; R2 represents a group R10—(X)n-(ALK)m— wherein R10, ALK, X, m and n are as defined in the specification; R3 represents hydrogen, (C1–C6) alkyl or phenyl(C1–C6)alkyl-; and R5 and R6 are as defined in the specification.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: February 6, 2007
    Assignee: British Biotech Pharmaceuticals Limited
    Inventors: Paul Raymond Beckett, Steven Launchbury, Gilles Pain, Lisa Marie Pratt
  • Publication number: 20060276409
    Abstract: Compounds of formula (I) are antibacterials: wherein: R1 represents hydrogen, or C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 represents a group R10—(X)n-(ALK)m- wherein R10 represents hydrogen, or a C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, any of which may be unsubstituted or substituted by (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy, mercapto, (C1-C6)alkylthio, amino, halo (including fluoro, chloro, bromo and iodo), trifluoromethyl, cyano, nitro, —COOH, —CONH2, —COORA, —NHCORA, —CONHRA, —NHRA, —NRARB, or —CONRARB wherein RA and RB are independently a (C1-C6)alkyl group, and ALK represents a straight or branched divalent C1-C6 alkylene, C2-C6 alkenylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent —NH—, —O— or —S— linkages, X represents —NH—, —O— or —S—, and m and n are independently 0 or 1; and A represents a group as defined in the specification.
    Type: Application
    Filed: August 2, 2006
    Publication date: December 7, 2006
    Applicant: British Biotech Pharmaceuticals Ltd.
    Inventors: Michael Hunter, Raymond Beckett, John Clements, Mark Whittaker, Stephen Davies, Lisa Pratt, Zoe Spavold, Steven Launchbury
  • Publication number: 20060211732
    Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:
    Type: Application
    Filed: August 22, 2005
    Publication date: September 21, 2006
    Applicant: British Biotech Pharmaceuticals Ltd.
    Inventors: Michael George Hunter, Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Spavold
  • Patent number: 6992190
    Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: January 31, 2006
    Assignee: British Biotech Pharmaceuticals Ltd.
    Inventors: Michael George Hunter, Paul Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Marie Spavold
  • Publication number: 20050159412
    Abstract: Compounds of formula (I) are antibacterial agents: wherein: Z is —N(OH)CH(?O) or —C(?O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl or, except when Z is a radical of formula —N(OH)CH(?O), a hydroxy, halo or amino group; R2, R3 and R4 independently represents hydrogen or a group R10-(D)n-(ALK)m- wherein R10, D, n, m and ALK are as defined in the claims; or R3 and R4 taken together with the nitrogen atom to which they are attached form an optionally substituted monocyclic heterocyclic ring containing from 5 to 7 ring atoms, one of which is the nitrogen atom to which R4 and R5 are attached and the remaining ring atoms being selected from compatible combinations of carbon, oxygen, sulfur and nitrogen.
    Type: Application
    Filed: November 27, 2002
    Publication date: July 21, 2005
    Applicant: DE NOVO PHARMACEUTICALS LIMITED
    Inventors: Paul Gane, Barry Porter, Henriette Willems, Raymond Beckett, Kenneth Keavey
  • Publication number: 20050014702
    Abstract: Compounds of formula (I) are antibacterials: wherein: R1 represents hydrogen, or C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 represents a group R10—(X)n-(ALK)m- wherein R10 represents hydrogen, or a C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, any of which may be unsubstituted or substituted by (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy, mercapto, (C1-C6)alkylthio, amino, halo (including fluoro, chloro, bromo and iodo), trifluoromethyl, cyano, nitro, —COOH, —CONH2, —COORA, —NHCORA, —CONHRA, —NHRA, —NRARB, or —CONRARB wherein RA and RB are independently a (C1-C6)alkyl group, and ALK represents a straight or branched divalent C1-C6 alkylene, C2-C6 alkenylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent —NH—, —O— or —S— linkages, X represents —NH—, —O— or —S—, and m and n are independently 0 or 1; and A represents a group as defined in the specification.
    Type: Application
    Filed: July 29, 2004
    Publication date: January 20, 2005
    Applicant: British Biotech Pharmaceuticals Ltd.
    Inventors: Michael Hunter, Raymond Beckett, John Clements, Mark Whittaker, Stephen Davies, Lisa Pratt, Zoe Spavold, Steven Launchbury
  • Publication number: 20040106666
    Abstract: 1
    Type: Application
    Filed: November 10, 2003
    Publication date: June 3, 2004
    Inventors: Paul Raymond Beckett, Steven Launchbury, Gilles Pain, Lisa Marie Pratt
  • Publication number: 20040102491
    Abstract: Compounds of formula (I) and (IA) have antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH(═O) or of formula C(═O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of formula N(OH)CH(═O), a hydroxy or amino group; R2 represents a radical of formula R10—(X)n-(ALK)m— wherein R10 represents hydrogen, or an optionally substituted c1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, ALK represents a straight or branched divalent C1-C6 alkylene, C2-C6 ?alkenylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent NH—, —O— or S— linkages, X represents NH—, —O— or S—, and m and n are independently 0 or 1; R3 represents hydrogen, C1-C6alkyl, or benzyl; and R4 is as defined in the specification.
    Type: Application
    Filed: December 30, 2003
    Publication date: May 27, 2004
    Inventors: Barry Porter, Paul Gane, Raymond Beckett, Kenneth Keavey, Jac Wijkmans, Lydia Saroglou
  • Publication number: 20020198241
    Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof: 1
    Type: Application
    Filed: June 26, 2002
    Publication date: December 26, 2002
    Applicant: British Biotech Pharmaceuticals Ltd.
    Inventors: Michael George Hunter, Paul Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Marie Spavold