Patents by Inventor Raymond Birge

Raymond Birge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10851096
    Abstract: Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: December 1, 2020
    Assignees: Rutgers, The State University of New Jersey, The Curators of the University of Missouri
    Inventors: William J. Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Thomas Walter Comollo, Stanley G. Kimani, Kamlendra Singh
  • Publication number: 20190127361
    Abstract: Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.
    Type: Application
    Filed: June 16, 2017
    Publication date: May 2, 2019
    Applicants: Rutgers, The State University of New Jersey, The Curators of the University of Missouri
    Inventors: William J. Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Thomas Walter Comollo, Stanley G. Kimani, Kamlendra Singh
  • Publication number: 20040266811
    Abstract: The present invention provides methods for enhancing regeneration or remyelination, and for inducing hypermyelination, of neurites in damaged nervous tissue. Additionally, the present invention provides a method for modulating gene expression in Schwann cells. The present invention is further directed to uses of immunophilin ligands to enhance regeneration or remyelination of neurites in damaged nervous tissue, to induce hypermyelination of neurites in damaged nervous tissue, and to modulate gene expression in Schwann cells. Also provided is a pharmaceutical composition, comprising GM-284 and a pharmaceutically acceptable carrier. The present invention is also directed to methods for treating a peripheral neuropathy in a subject in need of treatment. Finally, the present invention provides a use of GM-284 to treat a peripheral neuropathy in a subject in need of treatment.
    Type: Application
    Filed: November 8, 2002
    Publication date: December 30, 2004
    Inventors: David E. Weinstein, Scott Wadsworth, John Siekierka, Raymond Birge
  • Publication number: 20030072743
    Abstract: The present invention is directed to methods for enhancing the ability of the immune system to either increase or decrease a cellular immune response to an antigen, for the purpose of either enhancing effectiveness of, for example, anti-viral and anti-tumor responses or decreasing immunological reactions in, for example, autoimmune disease or organ rejection, respectively; or clearing certain antigens responsible for disease in order to prevent an immune response.
    Type: Application
    Filed: September 10, 2002
    Publication date: April 17, 2003
    Inventors: Matthew Albert, Raymond Birge