Patents by Inventor Raymond Bunch

Raymond Bunch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220389377
    Abstract: A method of treating medical conditions by stem cell therapy. Stem cells are transplanted into and onto a human or animal patient in need, Then stem cell proliferation is increased, activating migration to sites of inflammation and epigenetic effects, regenerating damaged tissues through inhibition of apoptosis, inhibition of inflammation and oxidative stress, and inducing angiogenesis and stem cell differentiation into various cells by administering substances that induce GSK-3 beta inhibition and HDAC inhibition.
    Type: Application
    Filed: August 15, 2022
    Publication date: December 8, 2022
    Inventors: James R. MUSICK, Tiana STATES, Raymond BUNCH
  • Publication number: 20160000926
    Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
    Type: Application
    Filed: February 27, 2015
    Publication date: January 7, 2016
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Daniel J. ABRAMS, Raymond BUNCH, Tom ANCHORDOQUY, Karen E. STEVENS
  • Publication number: 20140171383
    Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
    Type: Application
    Filed: June 28, 2013
    Publication date: June 19, 2014
    Inventors: Daniel J. ABRAMS, Raymond Bunch, Tom Anchordoquy
  • Publication number: 20140100183
    Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
    Type: Application
    Filed: April 12, 2013
    Publication date: April 10, 2014
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Daniel J. ABRAMS, Raymond BUNCH, Tom ANCHORDOQUY, Karen E. STEVENS
  • Publication number: 20120071432
    Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-ac-Live agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
    Type: Application
    Filed: March 18, 2011
    Publication date: March 22, 2012
    Applicant: The Regents of the University of Colorado
    Inventors: Daniel J. Abrams, Raymond Bunch, Tom Anchordoquy, Karen Elizabeth Stevens
  • Publication number: 20090221956
    Abstract: The invention generally relates to a multi-parameter monitoring device for in-line use to monitor a therapeutic agent solution passing therethrough prior to being centrally administered in connection with treatment of a CNS-related condition or disorder, e.g., a neuro-psychiatric disorder. In another aspect, the invention relates to a multi-parameter monitoring device for in-line use to monitor a therapeutic agent solution passing therethrough prior to being (a) intravenously administered to a patient in connection with a treatment, such as is the case where the therapeutic agent solution comprises an IV administerable solution, or (b) administered to a patient in connection with a treatment for diabetes, such as is the case where the therapeutic agent comprises insulin.
    Type: Application
    Filed: January 22, 2007
    Publication date: September 3, 2009
    Applicant: The Regents of the University of Colorado
    Inventors: Daniel J. Abrams, Raymond Bunch, Michael Royals
  • Publication number: 20090209480
    Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
    Type: Application
    Filed: January 17, 2007
    Publication date: August 20, 2009
    Applicant: The Regents of the University of Colorado
    Inventors: Daniel J. Abrams, Raymond Bunch, Tom Anchordoquy, Karen E. Stevens
  • Publication number: 20090069267
    Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
    Type: Application
    Filed: July 25, 2008
    Publication date: March 12, 2009
    Inventors: Daniel J. Abrams, Raymond Bunch, Tom Anchordoquy, Karen E. Stevens
  • Publication number: 20030100297
    Abstract: In a communication system, a privilege to access and to operate within a communication network (102) is granted to a terminal device (104) by use of a certificate from the communication network. In addition to granting privileges, the certificate may require the terminal device to update its software and configuration by requiring the terminal device to perform any combination of the following: downloading a different version of software and/or configuration, setting an allowable range of operation, and suspending operations outside of the allowed range. The communication network keeps a current list of type-approved software versions and configurations which the terminal device may utilize, and compares the software and configuration of the terminal device against the list to determine appropriate measures.
    Type: Application
    Filed: November 27, 2001
    Publication date: May 29, 2003
    Inventors: Kenneth B. Riordan, Steve Raymond Bunch, Kevin Michael Cutts