Patents by Inventor Raymond C. Grabiak

Raymond C. Grabiak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIPOLAR TRANS CARTENOID SALTS AND THEIR USES
    Publication number: 20170202798
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: January 30, 2017
    Publication date: July 20, 2017
    Applicant: DIFFUSION PHARMACEUTICALS LLC
    Inventors: John L. GAINER, Raymond C. GRABIAK
  • Bipolar trans carotenoid salts and their uses
    Patent number: 9604899
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: March 28, 2017
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • BIPOLAR TRANS CAROTENOID SALTS AND THEIR USES
    Publication number: 20140051759
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: September 17, 2012
    Publication date: February 20, 2014
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Patent number: 8269027
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: September 18, 2012
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Publication number: 20110294884
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 1, 2011
    Applicant: Diffusion Pharmaceuticals LLC
    Inventors: John Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Patent number: 8017653
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: September 13, 2011
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Publication number: 20110196038
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: April 4, 2011
    Publication date: August 11, 2011
    Applicant: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Patent number: 7919527
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: April 5, 2011
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Patent number: 7759506
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: August 25, 2003
    Date of Patent: July 20, 2010
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Publication number: 20100137436
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: January 25, 2010
    Publication date: June 3, 2010
    Applicant: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Patent number: 7351844
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: April 1, 2008
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Bipolar trans carotenoid salts and their uses
    Publication number: 20040116729
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: August 25, 2003
    Publication date: June 17, 2004
    Applicant: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Biopolar trans carotenoid salts and their uses
    Publication number: 20040014725
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: February 25, 2003
    Publication date: January 22, 2004
    Inventors: John L. Gainer, Raymond C. Grabiak
  • Process for the preparation of glyphosate and glyphosate derivatives
    Patent number: 5874612
    Abstract: A process for preparing glyphosate and other secondary amines of related structure in which a precursor primary amine such as aminomethylphosphonic acid is condensed with glyoxylic acid, or a related aldehyde compound, and the condensation product reduced without isolation to produce the desired product.
    Type: Grant
    Filed: February 5, 1990
    Date of Patent: February 23, 1999
    Inventors: Sherrol L. Baysdon, Raymond C. Grabiak, Thomas E. Rogers, Lowell R. Smith
  • Paramagnetic complexes of N-alkyl-N-hydroxylamides of organic acids and emulsions containing same for magnetic resonance imaging (MRI)
    Patent number: 5614170
    Abstract: Emulsions of paramagnetic contrast agents, and processes of making and using them are disclosed. The emulsions contain water, a dispersed oil phase and a complex of a paramagnetic metal ion and an organic acid chelator, for example DTPA (diethylenetriaminepentaacetic acid), having a C.sub.10 -C.sub.30 saturated aliphatic group and an hydroxyl group bonded to the nitrogen atom. The emulsions are very stable and therapeutically acceptable for intravenous administration to enhance MRI imaging.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: March 25, 1997
    Assignee: HemaGen/PFC
    Inventors: William P. Cacheris, Thomas J. Richard, Raymond C. Grabiak, Albert C. Lee
  • Emulsions of paramagnetic contrast agents for magnetic resonance imaging (MRI).
    Patent number: 5571498
    Abstract: Emulsions of paramagnetic contrast agents, and processes of making and using them are disclosed. The emulsions contain water, a dispersed oil phase and a complex of a paramagnetic metal ion and an organic chelator having a C.sub.10 -C.sub.30 unsaturated aliphatic group. The emulsions are very stable and therapeutically acceptable for intravenous administration to enhance MRI.
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: November 5, 1996
    Assignee: HemaGen/PFC
    Inventors: William P. Cacheris, Robert J. Kaufman, Thomas J. Richard, Raymond C. Grabiak
  • Process for producing N-phosphonomethylglycine
    Patent number: 5072033
    Abstract: A process for the production of N-phosphonomethylglycine comprising contacting N-phosphonomethyliminodiacetic acid with a peroxide in the presence of a catalyst selected from the group consisting of the salts and salt complexes of cobalt and vanadium, and an effective amount of a quinone or hydroquinone.
    Type: Grant
    Filed: December 11, 1990
    Date of Patent: December 10, 1991
    Assignee: Monsanto Company
    Inventors: Donald L. Fields, Jr., Raymond C. Grabiak, Karl E. Koenig, Dennis P. Riley
  • Process for producing N-phosphonomethylgylcine
    Patent number: 5061820
    Abstract: A process for the production of N-phosphonomethylglycine comprising contacting N-phosphonomethyliminodiacetic acid with a peroxide in the presence of a catalyst selected from the group consisting of the salts and salt complexes of cobalt and vancadium, and an effective amount of dipyridyl compound.
    Type: Grant
    Filed: October 22, 1990
    Date of Patent: October 29, 1991
    Assignee: Monsanto Company
    Inventors: Donald L. Fields, Jr., Raymond C. Grabiak, Karl E. Koenig, Dennis P. Riley
  • 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes
    Patent number: 5000775
    Abstract: 2-Amino-4,5-disubstituted-oxazole/thiazole compounds and antidotes for thiocarbamate, triazine and acetamide herbicides. These antidote compounds are especially effective to safen acetamide herbicides used to control grassy weeds in sorghum and broadleaf weeds in corn.
    Type: Grant
    Filed: December 31, 1985
    Date of Patent: March 19, 1991
    Assignee: Monsanto Company
    Inventors: Raymond C. Grabiak, Robert K. Howe, Len F. Lee
  • Process for producing N-phosphonomethylglycine
    Patent number: 4952723
    Abstract: A process for the production of N-phosphonomethylglycine comprising contacting N-phosphonomethyliminodiacetic acid with a molecular oxygen-containing gas in the presence of a catalyst selected from the group consisting of the salts and salt complexes of manganese, cobalt, iron, nickel, chromium, ruthenium, aluminum, moleybdenum, vanadium and cerium, and an effective amount of a dipyridyl compound.
    Type: Grant
    Filed: July 31, 1989
    Date of Patent: August 28, 1990
    Assignee: Monsanto Company
    Inventors: Donald L. Fields, Jr., Raymond C. Grabiak, Dennis P. Riley