Patents by Inventor Raymond Colburn

Raymond Colburn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of measuring the biological activity of an urotensin II receptor
    Patent number: 7939052
    Abstract: Administration of U-II to rats caused an increase in the redness or the skin temperature of the ear of the rats. The increase was inhibited by compounds that decease the biological activity of the U-II/UT receptor. Thus, the present invention provides methods of measuring the biological activity of an U-II receptor by monitoring the redness or the skin temperature of the ear of an animal, and the use of the methods to test compounds for their abilities to increase or decrease the biological activity of an U-II receptor.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: May 10, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Robert Schulingkamp, Jianshen Qi, Raymond Colburn, Dennis Stone, Christopher Van Besien, Lisa Minor, Patricia Andrade-Gordon, Bruce Damiano
  • COLD MENTHOL RECEPTOR-1 ANTAGONISTS
    Publication number: 20080027029
    Abstract: The invention is directed to TRPM8 antagonists of Formula (I). More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating TRPM8-mediated disorders. Pharmaceutical and veterinary compositions and methods of treating pain and various other disease states or conditions using compounds of the invention are also described.
    Type: Application
    Filed: May 9, 2007
    Publication date: January 31, 2008
    Inventors: Raymond Colburn, Scott Dax, Christopher Flores, Jay Matthews, Ning Qin, Laura Reany, Christopher Teleha, Mark Youngman
  • Method of measuring the biological activity of an urotensin II receptor
    Publication number: 20060280686
    Abstract: Administration of U-II to rats caused an increase in the redness or the skin temperature of the ear of the rats. The increase was inhibited by compounds that decease the biological activity of the U-II/UT receptor. Thus, the present invention provides methods of measuring the biological activity of an U-II receptor by monitoring the redness or the skin temperature of the ear of an animal, and the use of the methods to test compounds for their abilities to increase or decrease the biological activity of an U-II receptor.
    Type: Application
    Filed: May 11, 2006
    Publication date: December 14, 2006
    Inventors: Robert Schulingkamp, Jianshen Qi, Raymond Colburn, Dennis Stone, Christopher Van Besien, Lisa Minor, Patricia Andrade-Gordon, Bruce Damiano