Abstract: A device for performing a remote ischemic conditioning treatment. The device includes an inflatable cuff and a cartridge which is a source of gas for inflating the cuff. A first valve controls the flow of gas from the cartridge to the cuff so as to maintain a predetermined pressure in the cuff during an ischemic period. A second valve allows gas to escape from the cuff during a reperfusion period of the remote ischemic conditioning treatment. A controller which may be battery-powered is used to control the opening and closing of the valves. The cartridge may contain a gas, or materials which, under certain conditions, react to produce a gas. The chemical reaction may be initiated by an electrical pulse or signal from the controller.

Abstract: A device for performing a remote ischemic conditioning treatment. The device includes an inflatable cuff and a cartridge which is a source of gas for inflating the cuff. A first valve controls the flow of gas from the cartridge to the cuff so as to maintain a predetermined pressure in the cuff during an ischemic period. A second valve allows gas to escape from the cuff during a reperfusion period of the remote ischemic conditioning treatment. A controller which may be battery-powered is used to control the opening and closing of the valves. The cartridge may contain a gas, or materials which, under certain conditions, react to produce a gas. The chemical reaction may be initiated by an electrical pulse or signal from the controller.

Abstract: A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.

Abstract: A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.

Abstract: A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.

Abstract: A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.

Abstract: The present invention provides an automated analyzer system for performing chemical, biochemical or biological assays using changes/no changes in diffraction of light by the presence/absence of analytes which may or may not be present in a sample binding to their analyte specific receptors laid out in a preselected pattern in a disposable sensor. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, and optical generation of laser light beams and detectors for detecting for diffracted light. An internal processor is included for automating the instrument, and a user interface to provide communication with the operator.

Abstract: The present invention relates to novel methods of producing oligonucleotides. In particular, the present invention provides an efficient, safe, and automated process for the production of large quantities of oligonucleotides.

Abstract: A mooring cover comprises an apron for substantially surrounding a dock mooring. The apron may have two or more rows of self draining pockets arranged along its length for storing boating accessories and a fastener for securing the opposite ends of the apron about the mooring. A top cover may be provided for covering the top of the mooring as the mooring cover is mounted thereto. In an alternate embodiment, the mooring cover mounts to a railing extending along a dock. In this embodiment, the mooring cover also has an apron with a plurality of self draining pockets arranged along its length for storing boating accessories; however, the mooring cover has a flap extending from the apron adapted to wrap around and attach to the apron for securing the mooring cover to the railing.

Abstract: The present invention provides disposable, semi-reusable, or single use reaction vessels with integrated optical elements for use with diffraction based assay systems. The vessel for assaying liquids for analytes includes a housing having at least one chamber or well for receiving a liquid therein and an optical element integrally formed with the housing for directing an incident light beam towards the well or chamber and directing a light beam away from the chamber after the light beam has interacted with analytes present in the liquid. The vessel may be test tube such as a blood collection tube, with or without, an optical element but having a pattern of analyte-specific receptors located on an inner surface of the tube wall so that when a liquid is introduced into the interior of the test tube analytes present in the liquid can bind with the pattern of analyte-specific receptors.

Abstract: The present invention provides an apparatus for producing patterns on a surface of a substrate. The apparatus includes a rigid support member such as a rigid tubular structure having first and second opposed ends and a fluid flow passageway extending therethrough. A printing stamp is attached at one of the opposed ends of the rigid support member. The printing stamp has a flexible diaphragm portion which has an outer surface which is coated with one or more materials in a pre-selected pattern. A pneumatic pressurizing mechanism communicating with an inner surface of the flexible diaphragm portion through the fluid flow passageway is used to bias the flexible diaphragm portion outwardly into intimate and substantially uniform contact with the surface of the substrate for transferring the pre-selected pattern onto said surface. The rigid tubular supports are attached to a robotic positioning mechanism for providing control of positioning of the stamp relative to the substrate surface.

Abstract: A mooring cover comprises an apron for substantially surrounding a dock mooring. The apron may have two or more rows of self draining pockets arranged along its length for storing boating accessories and a fastener for securing the opposite ends of the apron about the mooring. A top cover may be provided for covering the top of the mooring as the mooring cover is mounted thereto. In an alternate embodiment, the mooring cover mounts to a railing extending along a dock. In this embodiment, the mooring cover also has an apron with a plurality of self draining pockets arranged along its length for storing boating accessories; however, the mooring cover has a flap extending from the apron adapted to wrap around and attach to the apron for securing the mooring cover to the railing.

Abstract: A child-resistant fluid delivery device, comprising a container for storing fluid to be dispensed by the fluid delivery device and a wand assembly connected to the container. The wand assembly having a nozzle at a distal end through which fluid may be dispensed and a child-resistant connector at a proximal end. A ratchet mechanism is formed on the exterior of the child-resistant connector to permit attachment of the connector to the container and thereafter prevent removal of the connector from the container. The nozzle is sealed by a removable, child-resistant cover that includes at least one member that engages the nozzle to resist removal therefrom.

Abstract: A child-resistant fluid delivery device, comprising a container for storing fluid to be dispensed by the fluid delivery device and a wand assembly connected to the container. The wand assembly having a nozzle at a distal end through which fluid may be dispensed and a child-resistant connector at a proximal end. A ratchet mechanism is formed on the exterior of the child-resistant connector to permit attachment of the connector to the container and thereafter prevent removal of the connector from the container. The nozzle is sealed by a removable, child-resistant cover that includes at least one member that engages the nozzle to resist removal therefrom.

Abstract: A child-resistant fluid delivery device, comprising a container for storing fluid to be dispensed by the fluid delivery device and a wand assembly connected to the container. The wand assembly having a nozzle at a distal end through which fluid may be dispensed and a child-resistant connector at a proximal end. A ratchet mechanism is formed on the exterior of the child-resistant connector to permit attachment of the connector to the container and thereafter prevent removal of the connector from the container. The nozzle is sealed by a removable, child-resistant cover that includes at least one member that engages the nozzle to resist removal therefrom.

Abstract: A child-resistant fluid delivery device, comprising a container for storing fluid to be dispensed by the fluid delivery device and a wand assembly connected to the container. The wand assembly having a nozzle at a distal end through which fluid may be dispensed and a child-resistant connector at a proximal end. A ratchet mechanism is formed on the exterior of the child-resistant connector to permit attachment of the connector to the container and thereafter prevent removal of the connector from the container. The nozzle is sealed by a removable, child-resistant cover that includes at least one member that engages the nozzle to resist removal therefrom.

Abstract: A forced air heating apparatus for providing automatic cyclical heating and cooling of biological samples includes a housing and a heating chamber within the housing. The heating chamber supports a biological sample tray for supporting a plurality of sample containers. A heating device and an impeller are provided to heat the heating chamber and to direct heated air over the sample containers. The heating chamber is sealed to prevent escape of materials and includes a vent coupled to a filter to maintain ambient pressure in the heating chamber and trap particulate materials passing through the vent.

Abstract: A compression sprayer is provided with a bag in the tank for holding the product to be sprayed. The bag may be initially provided in folded, collapsed, sealed condition containing the product in concentrated form. The folded bag is then mounted interiorially of the tank and filled with liquid to provide the solution to be sprayed. The bag unfolds as it is filled and thereafter is coupled with the tank outlet. An internally mounted pump assembly pressurizes the interior of the tank to compress the bag which collapses as the contained liquid is sprayed.

Abstract: A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.