Abstract: Medical devices and systems for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a guidewire having a distal end and defining a lumen. A stiffening rod may be slidably disposed within the lumen. The stiffening rod may have a distal end and a distal end region disposed adjacent to the distal end. The stiffening rod may be configured to shift between a first position where the distal end of the stiffening rod is disposed proximally of the distal end of the guidewire and a second position where the distal end of the stiffening rod is disposed distally of the distal end of the guidewire.

Abstract: Systems and methods for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a handle having a base, a first carriage translatable relative to the base, and a second carriage translatable relative to the base. A sheath may be coupled to the first carriage. The system may also include a catheter shaft having a proximal end region and a steerable distal end region. The proximal end region may be coupled to the second carriage. A needle may be releasably coupled to the handle. The needle may be configured to pass through tissue into a position along the biliary and/or pancreatic tract. The system may also include a steering member having a first end coupled to the steerable distal end region of the catheter shaft and a second end disposed adjacent to the handle.

Abstract: Medical devices and systems for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a guidewire having a distal end and defining a lumen. A stiffening rod may be slidably disposed within the lumen. The stiffening rod may have a distal end and a distal end region disposed adjacent to the distal end. The stiffening rod may be configured to shift between a first position where the distal end of the stiffening rod is disposed proximally of the distal end of the guidewire and a second position where the distal end of the stiffening rod is disposed distally of the distal end of the guidewire.

Abstract: Medical devices and systems for treating a stricture along the biliary and/or pancreatic tract are disclosed. An example medical device may include a guidewire for use along the biliary and/or pancreatic tract. The guidewire may include an elongate core member having a proximal end region and a distal end region. A coil member may be disposed along the distal end region. An actuation member may be coupled to the coil member. The actuation member may be configured to shift the coil member between a first configuration and a compressed configuration. The coil member may be configured to be advanced across a biliary and/or pancreatic stricture when in the compressed configuration. A sleeve may be disposed over the coil member.

Abstract: Medical devices for use along the biliary and/or pancreatic tract. An example system for treating a stricture, for example along the biliary and/or pancreatic tract, may include a guidewire for antegrade stricture crossing along the biliary and/or pancreatic tract. The guidewire may have a distal end region and a proximal end region. A hub may be coupled to the proximal end region. A tubular sheath may be slidably disposed along the guidewire. The tubular sheath may have a plurality of slots formed therein. The hub may be configured to secure the axial position of the tubular sheath relative to the guidewire.

Abstract: Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body.

Abstract: Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body.

Abstract: Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body.

Abstract: Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body.

Abstract: Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body.

Abstract: Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body.