Abstract: A one-piece mold can be used to form molded items that incorporate features or encroachments with negative draft angles, and such molded items can be removed from the mold in a single piece by lifting, tilting, or pulling, or a combination thereof, without breaking the mold or the item to be molded. The mold and method of molding are suited to a bathtub or shower unit. The mold and method of molding permit the removal of molded items with negative draft angles by coordinating the angle of the sump front wall and sump back wall with the angles of other encroachments in the molded item within specified ranges that permit one-piece removal of the item to be molded from the mold.

Abstract: A one-piece mold can be used to form molded items that incorporate features or encroachments with negative draft angles, and such molded items can be removed from the mold in a single piece by lifting, tilting, or pulling, or a combination thereof, without breaking the mold or the item to be molded. The mold and method of molding are suited to a bathtub or shower unit. The mold and method of molding permit the removal of molded items with negative draft angles by coordinating the angle of the sump front will and sump back wall with the angles of other encroachments in the molded item within specified ranges that permit one-piece removal of the item to be molded from the mold.

Abstract: A one-piece mold can be used to form molded items that incorporate features or encroachments with negative draft angles, and such molded items can be removed from the mold in a single piece by lifting, tilting, or pulling, or a combination thereof, without breaking the mold or the item to be molded. The mold and method of molding are suited to a bathtub or shower unit. The mold and method of molding permit the removal of molded items with negative draft angles by coordinating the angle of the sump front wall and sump back wall with the angles of other encroachments in the molded item within specified ranges that permit one-piece removal of the item to be molded from the mold.

Abstract: A one-piece mold can be used to form molded items that incorporate features or encroachments with negative draft angles, and such molded items can be removed from the mold in a single piece by lifting, tilting, or pulling, or a combination thereof, without breaking the mold or the item to be molded. The mold and method of molding are suited to a bathtub or shower unit. The mold and method of molding permit the removal of molded items with negative draft angles by coordinating the angle of the sump front will and sump back wall with the angles of other encroachments in the molded item within specified ranges that permit one-piece removal of the item to be molded from the mold.

Abstract: A one-piece mold can be used to form molded items that incorporate features or encroachments with negative draft angles, and such molded items can be removed from the mold in a single piece by lifting, tilting, or pulling, or a combination thereof, without breaking the mold or the item to be molded. The mold and method of molding are suited to a bathtub or shower unit. The mold and method of molding permit the removal of molded items with negative draft angles by coordinating the angle of the sump front wall and sump back wall with the angles of other encroachments in the molded item within specified ranges that permit one-piece removal of the item to be molded from the mold.

Abstract: Methods and compositions are provided for forming complexes between dsDNA and novel oligomers comprising fused six-membered rings. By appropriate choice of target sequences and oligomers, complexes comprising oligomer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.

Abstract: Methods and compositions are provided for forming complexes between dsDNA and novel DNA-binding polymers comprising N-terminal thiophene-containing moieties which exhibit selectivity for T-A base pairs. By appropriate choice of target sequences and DNA-binding polymers, complexes comprising polymer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.

Abstract: Methods and compositions are provided for forming complexes between dsDNA and novel DNA-binding polymers comprising N-terminal thiophene-containing moieties which exhibit selectivity for T-A base pairs. By appropriate choice of target sequences and DNA-binding polymers, complexes comprising polymer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.

Abstract: Methods and compositions are provided for forming complexes between dsDNA and novel DNA-binding polymers comprising N-terminal thiophene-containing moieties which exhibit selectivity for T-A base pairs. By appropriate choice of target sequences and DNA-binding polymers, complexes comprising polymer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.

Abstract: Methods and compositions are provided for forming complexes between dsDNA and novel DNA-binding polymers comprising N-terminal thiophene-containing moieties which exhibit selectivity for T-A base pairs. By appropriate choice of target sequences and DNA-binding polymers, complexes comprising polymer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.

Abstract: Methods and compositions are provided for forming complexes between dsDNA and novel oligomers comprising fused six-membered rings. By appropriate choice of target sequences and oligomers, complexes comprising oligomer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.