Patents by Inventor Raymond Franck RAZAFINDRAINIBE

Raymond Franck RAZAFINDRAINIBE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THIOPHENOXIME AND FURANOXIME SCAFFOLDS
    Publication number: 20230357212
    Abstract: The present invention relates to a compound of formula (I). It also relates to a pharmaceutical composition comprising at least one compound of formula (I) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorous nerve agent; in the treatment of neurological diseases such as Alzheimer’s disease; and/or in the treatment of cancer.
    Type: Application
    Filed: September 10, 2021
    Publication date: November 9, 2023
    Inventors: Rachid BAATI, Mallikarjuna Reddy NIMMAKAYALA, José DIAS, Florian NACHON, Camille VOROS, Raymond Franck RAZAFINDRAINIBE
  • DIAZINOXIMES SCAFFOLDS
    Publication number: 20230278980
    Abstract: The present invention relates to a compound of formulas (II) to (V). It also relates to a pharmaceutical composition comprising at least one compound of formulas (II) to (V) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorus nerve agent by reactivation of hAChE; in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer.
    Type: Application
    Filed: September 10, 2021
    Publication date: September 7, 2023
    Inventors: Rachid BAATI, Mallikarjuna Reddy NIMMAKAYALA, José DIAS, Florian NACHON, Camille VOROS, Raymond Franck RAZAFINDRAINIBE
  • THIAZOLOXIME AND OXAZOLOXIME DERIVATIVES AS REACTIVATORS OF ORGANOPHOSPHOROUS NERVE AGENT (OPNA)-INHIBITED HUMAN ACETYLCHOLINESTERASE FOR THE TREATMENT OF NERVOUS AND/OR RESPIRATORY FAILURE AFTER INTOXICATION WITH OPNA
    Publication number: 20230203024
    Abstract: The present invention relates to a compound of formula (I). It also relates to a pharmaceutical composition comprising at least one compound of formula (I) and at least one pharmaceutically acceptable support. Finally, it relates to the compounds of formula (I) for use in a method of medical treatment, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organo-phosphorous nerve agent (OPNA); in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer. The compounds act as reactivators of OPNA-inhibited hAChE (human acetylcholinesterase).
    Type: Application
    Filed: May 25, 2021
    Publication date: June 29, 2023
    Inventors: Rachid BAATI, José DIAS, Florian NACHON, Raymond Franck RAZAFINDRAINIBE, Mallikarjuna Reddy NIMMAKAYALA, Camille VOROS