Patents by Inventor Raymond Furgal

Raymond Furgal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDES WITH ETHYLENE GLYCOL MODIFICATION
    Publication number: 20250145992
    Abstract: The disclosure relates to compositions, systems, and methods comprising ethylene glycol chemical modifications on oligonucleotides to modulate silencing activity and improve stability.
    Type: Application
    Filed: October 17, 2024
    Publication date: May 8, 2025
    Inventors: Anastasia Khvorova, Daniel O'Reilly, Vignesh Narayan Hariharan, Raymond Furgal, Katherine Gross
  • DENDRITIC CONJUGATES FOR THE SKIN DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    Publication number: 20240350526
    Abstract: This disclosure provides compositions, systems, and methods for the delivery of therapeutic oligonucleotides to the skin. The oligonucleotide is conjugated to a dendron comprising a hydrophilic end group, a phosphate group, and/or a hydrophobic chain.
    Type: Application
    Filed: March 1, 2024
    Publication date: October 24, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, Qi Tang, Katherine Gross, John E. Harris, Julia Alterman, Mohammad Zain Ul Abideen, Raymond Furgal
  • TOPICAL DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    Publication number: 20240325546
    Abstract: This disclosure provides compositions, systems, and methods for the topical delivery of therapeutic oligonucleotides with microneedle particles.
    Type: Application
    Filed: March 1, 2024
    Publication date: October 3, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, Qi Tang, John E. Harris, Julia Alterman, Mohammad Zain Ul Abideen, Raymond Furgal