Patents by Inventor Raymond Hickey

Raymond Hickey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fumarylacetoacetate hydrolase (Fah)-deficient pigs and uses thereof
    Patent number: 9485971
    Abstract: Described herein is the generation of Fah+/? heterozygote pigs by homologous recombination and somatic cell nuclear transfer, and a method for producing Fah?/? homozygote pigs. The Fah-deficient pigs of the disclosure can be used for a variety of research and therapeutic purposes, such as for the expansion of human hepatocytes, and as large animal models of hereditary tyrosinemia type 1, cirrhosis and hepatocellular carcinoma.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: November 8, 2016
    Assignees: Oregon Health & Science University, Mayo Foundation for Medical Education and Research
    Inventors: Scott Nyberg, Markus Grompe, Joseph Lillegard, Raymond Hickey
  • FUMARYLACETOACETATE HYDROLASE (FAH)-DEFICIENT PIGS AND USES THEREOF
    Publication number: 20150181844
    Abstract: Described herein is the generation of Fah+/? heterozygote pigs by homologous recombination and somatic cell nuclear transfer, and a method for producing Fah?/? homozygote pigs. The Fah-deficient pigs of the disclosure can be used for a variety of research and therapeutic purposes, such as for the expansion of human hepatocytes, and as large animal models of hereditary tyrosinemia type 1, cirrhosis and hepatocellular carcinoma.
    Type: Application
    Filed: March 13, 2015
    Publication date: July 2, 2015
    Applicants: OREGON HEALTH & SCIENCE UNIVERSITY, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Scott Nyberg, Markus Grompe, Joseph Lillegard, Raymond Hickey
  • Fumarylacetoacetate hydrolase (fah)-deficient pigs and uses thereof
    Patent number: 9000257
    Abstract: Described herein is the generation of Fah+/? heterozygote pigs by homologous recombination and somatic cell nuclear transfer, and a method for producing Fah?/? homozygote pigs. The Fah-deficient pigs of the disclosure can be used for a variety of research and therapeutic purposes, such as for the expansion of human hepatocytes, and as large animal models of hereditary tyrosinemia type 1, cirrhosis and hepatocellular carcinoma.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: April 7, 2015
    Assignees: Oregon Health & Science University, Mayo Foundation for Medical Education and Research
    Inventors: Markus Grompe, Scott Nyberg, Joseph Lillegard, Raymond Hickey
  • FUMARYLACETOACETATE HYDROLASE (FAH)-DEFICIENT PIGS AND USES THEREOF
    Publication number: 20130191931
    Abstract: Described herein is the generation of Fah+/? heterozygote pigs by homologous recombination and somatic cell nuclear transfer, and a method for producing Fah?/? homozygote pigs. The Fah-deficient pigs of the disclosure can be used for a variety of research and therapeutic purposes, such as for the expansion of human hepatocytes, and as large animal models of hereditary tyrosinemia type 1, cirrhosis and hepatocellular carcinoma.
    Type: Application
    Filed: March 23, 2011
    Publication date: July 25, 2013
    Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Markus Grompe, Scott Nyberg, Joseph Lillegard, Raymond Hickey