Abstract: Described herein is a system and method for correcting a visual field of a subject using a predicted visual field that includes visual field defects from facial contours of the subject. In an embodiment. the predicted visual field may be determined using a three-dimensional (3D) reconstruction of the face of the subject which may be generated from a two-dimensional (2D) image of the subject using a convolution neural network. A system and method for optimizing a head turn angle of a subject for determining a visual field of a subject is also described herein. An optimal head turn angle may be determined using the 3D reconstruction of the face of the subject. In some embodiments, after the visual field is maximized with positioning of the head. residual facial contour induced defects can be predicted and a final corrected field can be generated.

Abstract: Embodiments of the invention include a method for manufacturing sensors and circuit structures. The method can include providing a substrate including a layer of polymer capable of producing graphite in response to the application of energy, a first electrode adjacent to a first via location on the layer of polymer, and an insulating layer over at least a portion of the first electrode and the layer of polymer at the first via location; and applying sufficient energy to the layer of polymer at the first via location through the insulating layer to ablate the insulating layer and to form a first via as mass of graphite that extends into electrical contact with the first electrode and is surrounded by the insulating layer in a plane of the insulating layer.

Abstract: This document provides methods and materials for performing retinal pigment epithelium transplantation. For example, methods and materials for using fibrin supports for retinal pigment epithelium transplantation are provided.

Abstract: Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Abstract: This document provides methods and materials for performing retinal pigment epithelium transplantation. For example, methods and materials for using fibrin supports for retinal pigment epithelium transplantation are provided.

Abstract: Embodiments of the invention include a method for manufacturing sensors and circuit structures. The method can include providing a substrate including a layer of polymer capable of producing graphite in response to the application of energy, a first electrode adjacent to a first via location on the layer of polymer, and an insulating layer over at least a portion of the first electrode and the layer of polymer at the first via location; and applying sufficient energy to the layer of polymer at the first via location through the insulating layer to ablate the insulating layer and to form a first via as mass of graphite that extends into electrical contact with the first electrode and is surrounded by the insulating layer in a plane of the insulating layer.

Abstract: Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Abstract: This document provides methods and materials for performing retinal pigment epithelium transplantation. For example, methods and materials for using fibrin supports for retinal pigment epithelium transplantation are provided.

Abstract: Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Abstract: Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Abstract: Methods are described for individualizing a patient's treatment for an eye disease that is mediated by vascular-derived endothelial growth factor.

Abstract: Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Abstract: Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Abstract: A self-assembled nanobump array structure including a semi-absorbing outer layer provided on at least one nanobump-forming substrate layer, the semi-absorbing outer layer configured to ablate slowly to allow an applied laser energy to be transmitted to the at least one nanobump-forming substrate layer, in which the self-assembled nanobump array structure is formed by an energy and a pressure buildup occurring in the at least one nanobump-forming substrate layer.

Abstract: A self-assembled nanobump array structure including a semi-absorbing outer layer provided on at least one nanobump-forming substrate layer, the semi-absorbing outer layer configured to ablate slowly to allow an applied laser energy to be transmitted to the at least one nanobump-forming substrate layer, in which the self-assembled nanobump array structure is formed by an energy and a pressure buildup occurring in the at least one nanobump-forming substrate layer.

Abstract: A drug delivery system includes a plurality of sites, a fluid channel for delivering a drug to one of the plurality sites, and a light channel for delivering light to an area near one of the plurality of sites. The fluid channel is a micro fluidic channel and the light channel is a wave guide. The light channel may also be a fiber optic cable. The light channel directs light at the fluid channel wherein light from the light channel does not substantially exit to the major surface. The drug delivery system selectively delivers drugs to various types of neurologic cells. In operation a solution of a photoactivatable neuro-active drug is delivered to a preselected area in vivo and photoactivated in the solution at the preselected area to stimulate neurological tissue. The neuro-active drug could be an antagonist or agonist of neuronal activity.

Abstract: A drug delivery system includes a plurality of sites, a fluid channel for delivering a drug to one of the plurality sites, and a light channel for delivering light to an area near one of the plurality of sites. The fluid channel is a micro fluidic channel and the light channel is a wave guide. The light channel may also be a fiber optic cable. The light channel directs light at the fluid channel wherein light from the light channel does not substantially exit to the major surface. The drug delivery system selectively delivers drugs to various types of neurologic cells. In operation a solution of a photoactivatable neuro-active drug is delivered to a preselected area in vivo and photoactivated in the solution at the preselected area to stimulate neurological tissue. The neuro-active drug could be an antagonist or agonist of neuronal activity.

Abstract: An ultrasonic probe which performs a two-dimensional scan is supported by a mount having a thread which is driven back and forth by a screw along a third axis. When a two-dimensional scan is completed in a first plane, a motor drives the mount along a guide to a second plane for the next scan. The separation between the planes being the same as the resolution in scanning within a plane. A housing having a slot with sidewalls is employed to guide the mount in traveling to successive plane locations along its axis. Means for orienting the housing in angular position and a support assembly provide moveable support to the orienting means so that minimal force is required to position the probe relative to the patient. An "auto-scroll" feature permits the operator to interactively pan through multiple, adjacent two-dimensional planes at programmable speeds and displacements along a third axis.