Patents by Inventor Raymond J. Dashaies

Raymond J. Dashaies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteolysis targeting chimeric pharmaceutical
    Patent number: 7208157
    Abstract: The present invention is based on the discovery of a composition that provides targeted ubiquitination. Specifically the composition contains a ubiquitin pathway protein binding moiety which recognizes a ubiquitin pathway protein and a targeting moiety which recognizes a target protein. In addition, the present invention provides libraries of compositions, where each composition contains a ubiquitin pathway protein binding moiety and a member of a molecular library. The libraries of the present invention can be used to identify proteins involved in a predetermined function of cells.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: April 24, 2007
    Assignees: California Institute of Technology, Yale University, The Regents of the University of California
    Inventors: Raymond J. Dashaies, Craig Crews, Kathleen M. Sakamoto
  • Proteolysis targeting chimeric pharmaceutical
    Publication number: 20040038358
    Abstract: The present invention is based on the discovery of a composition that provides targeted ubiquitination. Specifically the composition contains a ubiquitin pathway protein binding moiety which recognizes a ubiquitin pathway protein and a targeting moiety which recognizes a target protein. In addition, the present invention provides libraries of compositions, where each composition contains a ubiquitin pathway protein binding moiety and a member of a molecular library. The libraries of the present invention can be used to identify proteins involved in a predetermined function of cells.
    Type: Application
    Filed: November 18, 2002
    Publication date: February 26, 2004
    Inventors: Raymond J. Dashaies, Craig Crews, Kathleen M. Sakamoto