Patents by Inventor Raymond Paul Beckett

Raymond Paul Beckett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxamic acid derivatives
    Patent number: 5696082
    Abstract: Compounds of general formula (I) wherein X is --CONHOH or --CO.sub.2 H, principally characterised by the presence in substituent R.sub.3 and/or R.sub.4 of a group of formula (II) are inhibitors of matrix metalloproteinases and inhibitors of the production of turnout necrosis factor.
    Type: Grant
    Filed: May 28, 1996
    Date of Patent: December 9, 1997
    Assignee: British Biotech Pharmaceuticals Limited
    Inventors: Michael John Crimmin, Andrew Paul Ayscough, Raymond Paul Beckett
  • Hydroxamic acid derivatives as metalloproteinase inhibitors
    Patent number: 5652262
    Abstract: Compounds of general formula (I) wherein R.sup.1 represents a hydrogen atom or a C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl, phenyl, phenyl(C.sub.1 -C.sub.6)alkyl, C.sub.1 -C.sub.6 alkylthiomethyl, phenylthiomethyl, substituted phenylthiomethyl, phenyl(C.sub.1 -C.sub.6)alkylthiomethyl or heterocyclylthiomethyl group; or R.sup.1 represents --S--R.sup.x wherein R.sup.x represents a group .alpha.; R.sup.2 represents a hydrogen atom or a C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl, phenyl(C.sub.1 -C.sub.6)alkyl, cycloalkyl(C.sub.1 -C.sub.6)alkyl, or cycloalkenyl(C.sub.1 -C.sub.6)alkyl; R.sup.3 represents an amino acid side chain or a C.sub.1 -C.sub.6 alkyl, benzyl, (C.sub.1 -C.sub.6)alkoxybenzyl, benzyloxy(C.sub.1 -C.sub.6)alkyl or benzyloxybenzyl group; R.sup.4 represents a hydrogen atom or a methyl group; R.sup.5 represents a group (CH.sub.2).sub.n A; or R.sup.4 and R.sup.5 together represent a group .beta.; Q represents CH.sub.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: July 29, 1997
    Assignee: British Biotech Pharmaceutical, Ltd.
    Inventors: Michael John Crimmin, Raymond Paul Beckett, Mark Hampton Davis
  • Natural amino acid derivatives as metalloproteinase inhibitors
    Patent number: 5643964
    Abstract: Compounds of Formula (I) wherein R.sub.2 represents a group R.sub.6 --A-- wherein A represents a divalent straight or branched, saturated or unsaturated hydrocarbon chain of up to 6 C atoms which may be interrupted by an O or S atom, and R.sub.6 represents hydrogen or an optionally substituted phenyl, cycloalkyl or cycloalkenyl group; R.sub.3 represents the characterizing side chain of a natural alpha amino acid other than proline, and in which any polar substituents are optionally protected; R.sub.4 represents hydrogen or methyl; R.sub.5 represents hydrogen, C.sub.1 -C.sub.6 alkyl or a group D-(C.sub.1 -C.sub.6 alkyl) wherein D represents hydroxy, (C.sub.1 -C.sub.6)alkoxy, (C.sub.1 -C.sub.6)alkylthio, acylamino, optionally substituted phenyl, or a heterocyclic group, NH.sub.2, or a mono- or di-(C.sub.1 -C.sub.6 alkyl) amine or a heterocyclic group; or R.sub.3 and R.sub.
    Type: Grant
    Filed: January 23, 1995
    Date of Patent: July 1, 1997
    Assignee: British Biotech Pharmaceuticals Limited
    Inventors: Jonathan Philip Dickens, Michael John Crimmin, Raymond Paul Beckett