Patents by Inventor Raymond W. Kosley, Jr.

Raymond W. Kosley, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbamoyloxylabdane compounds useful in reducing intraocular pressure
    Patent number: 4920146
    Abstract: Novel carbamoyloxylabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure and treating cardiac failure utilizing compounds and compositions thereof are disclosed.
    Type: Grant
    Filed: December 28, 1987
    Date of Patent: April 24, 1990
    Assignee: Hoechst Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill, Gerard O'Malley
  • Hydrazinocarbonyloxylabdanes for treating cardiac failure
    Patent number: 4883793
    Abstract: Novel hydrazinocarbonyloxylabdanes, intermediates and processes for the preparation thereof, and a method for treating cardiac failure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: November 28, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Gerard J. O'Malley
  • Labdanes, pharmaceutical compositions, and their use
    Patent number: 4851397
    Abstract: Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: June 10, 1988
    Date of Patent: July 25, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Ethanobenzazepines
    Patent number: 4833244
    Abstract: Novel ethanobenzazepines, processes for the preparation thereof, and a method of alleviating pain utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: May 23, 1989
    Assignee: Hoechst-Rouseel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Bernhard Seuring
  • Piperidine intermediates
    Patent number: 4810792
    Abstract: Novel 3-methylenespiro[benzofuran-2(3H),4'-piperidines, intermediates and processes for the preparation thereof and methods for reducing blood pressure utilizing the compounds and compositions thereof are disclosed.
    Type: Grant
    Filed: August 15, 1988
    Date of Patent: March 7, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventor: Raymond W. Kosley, Jr.
  • 3-methylenespiro (benzofuranpiperidines)
    Patent number: 4788201
    Abstract: Novel 3-methylenespiro[benzofuran-2(3H),4'-piperidines], intermediates and processes for the preparation thereof and methods for reducing blood pressure utilizing the compounds and compositions thereof are disclosed.
    Type: Grant
    Filed: January 22, 1987
    Date of Patent: November 29, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventor: Raymond W. Kosley, Jr.
  • Labdanes, pharmaceutical compositions and use
    Patent number: 4771049
    Abstract: Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: March 16, 1987
    Date of Patent: September 13, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Intermediates for preparing ethanobenzazepines
    Patent number: 4723009
    Abstract: Novel ethanobenzazepines, processes for the preparation thereof, and a method of alleviating pain utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: October 14, 1986
    Date of Patent: February 2, 1988
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Raymond W. Kosley, Jr., Bernhard Seuring
  • Intermediates for spiro[2H-1,4 benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds
    Patent number: 4695637
    Abstract: Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
    Type: Grant
    Filed: December 19, 1985
    Date of Patent: September 22, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Labdane compounds, pharmaceutical compositions and use
    Patent number: 4677103
    Abstract: Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: June 30, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Aminoacyllabdanes
    Patent number: 4673752
    Abstract: Novel aminoacyllabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: June 16, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Process for preparing aminoacyllabdanes
    Patent number: 4672115
    Abstract: Novel aminoacyllabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: October 17, 1986
    Date of Patent: June 9, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'piperidine and -3'-pyrrolidine] compounds
    Patent number: 4668791
    Abstract: Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
    Type: Grant
    Filed: August 15, 1985
    Date of Patent: May 26, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Aminoacyllabdanes, pharmacuetical compositions and use
    Patent number: 4666904
    Abstract: Novel aminoacyllabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: May 19, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Aminoacyllabdanes, pharmaceutical compositions and use
    Patent number: 4639446
    Abstract: Novel aminoacyllabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: December 4, 1985
    Date of Patent: January 27, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Labdane compounds, pharmaceutical compositions and use
    Patent number: 4639443
    Abstract: Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: April 4, 1986
    Date of Patent: January 27, 1987
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds
    Patent number: 4579950
    Abstract: Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: April 1, 1986
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'piperidine] compounds
    Patent number: 4577026
    Abstract: Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: March 18, 1986
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds
    Patent number: 4569998
    Abstract: Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: February 11, 1986
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill
  • Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds and their use as antihypertensive agents
    Patent number: 4521537
    Abstract: Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
    Type: Grant
    Filed: April 2, 1984
    Date of Patent: June 4, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Incorporated
    Inventors: Raymond W. Kosley, Jr., Robert J. Cherill