Abstract: A “dry” packaging in which a prosthetic heart valve is packaged within a container with hydrogel that can be provided in many forms. Certain embodiments include hydrogel that is preloaded with glycerol or the like. The hydrogel regulates the humidity within the container through a diffusion-driven mechanism if a gradient of humidity between the inside and the outside of the hydrogel exists. Humidity regulation is important to prevent the tissue of the valve structure from drying out. When the partially-hydrated hydrogel is present within container, which is saturated with air of a predefined humidity, the water molecules from the air will be absorbed by the hydrogel if the air humidity is high (i.e. when the thermodynamics favor hydrogel hydration) or vice versa. Various embodiments are configured to also house at least a portion of a delivery device for delivering the prosthetic heart valve.

Abstract: Apparatuses, systems, and techniques for supporting fairness of multiple context sharing cryptographic hardware. An accelerator circuit includes a copy engine (CE) with AES-GCM hardware configured to perform both encryption and authentication of data transfers for multiple applications or multiple data streams in a single application or belonging to a single user. The CE splits a data transfer of a specified size into a set of partial transfers. The CE sequentially executes the set of partial transfers using a context for a period of time (e.g., a timeslice) for an application. The CE stores in a secure memory for the application one or more data for encryption or decryption (e.g., a hash key, a block counter, etc.) computed from a last partial transfer. The one or more data for encryption or decryption are retrieved and used when data transfers for the application is resumed by the CE.

Abstract: A crop prediction system performs various machine learning operations to predict crop production and to identify a set of farming operations that, if performed, optimize crop production. The crop prediction system uses crop prediction models trained using various machine learning operations based on geographic and agronomic information. Responsive to receiving a request from a grower, the crop prediction system can access information representation of a portion of land corresponding to the request, such as the location of the land and corresponding weather conditions and soil composition. The crop prediction system applies one or more crop prediction models to the access information to predict a crop production and identify an optimized set of farming operations for the grower to perform.

Abstract: An ergonomic power supply for a computer system includes a printed circuit board assembly configured to convert a mains electricity input to voltage-regulated, direct-current (DC) outputs. The printed circuit board assembly defines a mains input and has one or more DC output connectors. An enclosure houses a fan and the printed circuit board assembly. The enclosure has a rear panel, a front panel positioned opposite the rear panel relative to the printed circuit board assembly. A side panel is positioned between the front and rear panel. The mains connector extends through an aperture defined by the rear panel of the enclosure. The one or more DC output connectors extend through the side panel. Such an arrangement provides significantly easier access to the power supply outputs compared to conventional power supplies. Associated computer systems also are described.

Abstract: Antibodies, fragments thereof, and chimeric proteins comprising same are presented that have specific binding activity against T-cell immunoglobulin mucin receptor 3 (TIM3). Advantageously, contemplated molecules can be used in pharmaceutical compositions for immune therapy, particularly in individuals receiving cancer vaccines and/or checkpoint inhibitor treatment.

Abstract: Apparatuses, systems, and techniques for supporting fairness of multiple context sharing cryptographic hardware. An accelerator circuit includes a copy engine (CE) with AES-GCM hardware configured to perform both encryption and authentication of data transfers for multiple applications or multiple data streams in a single application or belonging to a single user. The CE splits a data transfer of a specified size into a set of partial transfers. The CE sequentially executes the set of partial transfers using a context for a period of time (e.g., a timeslice) for an application. The CE stores in a secure memory for the application one or more data for encryption or decryption (e.g., a hash key, a block counter, etc.) computed from a last partial transfer. The one or more data for encryption or decryption are retrieved and used when data transfers for the application is resumed by the CE.

Abstract: Antibodies, fragments thereof, and chimeric proteins comprising same are presented that have specific binding activity against T-cell immunoglobulin mucin receptor 3 (TIM3). Advantageously, contemplated molecules can be used in pharmaceutical compositions for immune therapy, particularly in individuals receiving cancer vaccines and/or checkpoint inhibitor treatment.

Abstract: The subject application relates to computing an authentication tag for partial transfers scheduled across multiple direct memory access (DMA) engines. Apparatuses, systems, and techniques are described for computing an authentication tag for a data transfer when the data transfer is scheduled as partial transfers across a specified number of direct memory access (DMA) engines. An orchestration circuit stores partial authentication tags, computed by the DMA engines, and corresponding adjustment exponents during one or more rounds in which the partial transfers are scheduled and processed by the specified number of DMA engines. During a last round, a combined authentication tag can be computed based on the partial authentication tags and the corresponding adjustment exponents stored by the orchestration circuit during the rounds.

Abstract: A novel combustion chamber valve and fuel system for driven fastener hand tool is disclosed having a fuel pump disposed parallel to the combustion and piston chambers. Pressure applied a safety at the nose of the tool is activates the fuel pump in a common direction. Pressure applied on a trigger activates the valve system prior to firing in a common direction. The valve system employs a central shaft coupling three valves, an inlet valve using a novel wedged circumferential edge seal, a control valve using a novel edge circumferential seal with a ventilated support, and a charging exhaust valve using a face seal.

Abstract: This invention provides a coffee maker having: an upper structure with a filter (1) and a measurement chamber (2); the measurement chamber (2) has TDS sensor (8), a temperature sensor (9) and a fluid transfer system (7); a lower structure with a weight sensor (52); a plurality of connecting elements (4) enacting the upper structure above the lower structure; and carafe (6) to be placed between the upper structure and lower structure; and a display panel (51) showing data from the TDS sensor, temperature sensor, or weight sensor.

Abstract: An exhaust valve comprising an elastomeric flap portion (e.g. of silicone) covering one or more exhaust ports in a normally closed position for a combustion driven fastener hand tool is disclosed. The elastomeric flap portion is much shorter than a comparable steel reed valve, allowing it to be disposed in small spaces. A single flat piece of elastomeric material can be configured held fixed to a housing surface along a line between one or more pairs of ports such that a flap portion of the material extends to each side of the line and covers one of the pairs of ports. The flat piece can be conveniently held in position against the housing surface by a rib or standoff on the interior surface of an exterior housing.

Abstract: An emergency determining system configured as part of a cellular or mobile network to receive emergency data from public safety answering points and to evaluate the emergency based at least in part on third party data, network data, and the emergency data. For instance, the emergency determining system may determine a level, a geographic area, and/or a response to the emergency and to broadcast, via the cellular or mobile network, notifications to individual's personal electronic devices within the geographic area to alert the individuals to the emergency and to provide instructions related to an appropriate response by the individual.

Abstract: Two-component vaccine formulations and methods are contemplated where the vaccine has an adjuvant component and a therapeutic component. The therapeutic component comprises preferably a recombinant therapeutic virus encoding a therapeutic antigen while the adjuvant component comprises a non-host cell or immune stimulating portion thereof. Notably, use of the adjuvant component will result in significant uptake of the therapeutic component into immune competent cells, even in the absence of receptors for entry of the therapeutic component. In addition, such adjuvant also stimulates expression of the therapeutic antigen.

Abstract: This invention provides a coffee maker having a top housing (2) connected to a bottom housing (3) via a plurality of connecting elements (4) such that the top housing is enacted above the bottom housing; a water tank (1) positioned on top of the top housing; a carafe (5) to be placed under the top housing, the carafe has an upper part having a brewing cone (51); and a rotating spout (6) located at the bottom of said top housing and above the carafe for pouring hot water into the carafe.

Abstract: Antibodies, fragments thereof, and chimeric proteins comprising same are presented that have specific binding activity against T-cell immunoglobulin mucin receptor 3 (TIM3). Advantageously, contemplated molecules can be used in pharmaceutical compositions for immune therapy, particularly in individuals receiving cancer vaccines and/or checkpoint inhibitor treatment.

Abstract: Aspects of the invention include receiving a request for data. The request is received from a computing element implementing a first bus protocol, and the data is accessible via a reduced instruction set computer (RISC) system implementing a plurality of bus protocols. A type of the received request is determined. A bus protocol is selected from the plurality of bus protocols based at least in part on the type of the received request. The received request is translated into a format that is compatible with the selected bus protocol and transmitted to the RISC system. Data is received from the RISC system in response to transmitting the translated request.

Abstract: A system, method and computer readable storage medium are disclosed to provide dynamic network resource management in a telecommunications network where at least a portion of the network resources are located at an edge of the telecommunications network. The capacity available, the aggregate demand of resources at a given time, and the cost of the network resource demanded as well as each customers upper price limit may be considered and adjusted in real-time by different network resource allocation models.

Abstract: Two-component vaccine formulations and methods are contemplated where the vaccine has an adjuvant component and a therapeutic component. The therapeutic component comprises preferably a recombinant therapeutic virus encoding a therapeutic antigen while the adjuvant component comprises a non-host cell or immune stimulating portion thereof. Notably, use of the adjuvant component will result in significant uptake of the therapeutic component into immune competent cells, even in the absence of receptors for entry of the therapeutic component. In addition, such adjuvant also stimulates expression of the therapeutic antigen.

Abstract: A semiconductor package including a lead frame, an Ag plated surface positioned on the lead frame, an adhesion promotion layer positioned on the top of the Ag plated surface, and mold body covering the top of the lead frame is provided. The Ag plated surface covers a significant part of an interconnection area of the lead frame surface, and the Ag plating surface does not exceed the area of the mold body.

Abstract: An emergency determining system configured as part of a cellular or mobile network to receive emergency data from public safety answering points and to evaluate the emergency based at least in part on third party data, network data, and the emergency data. For instance, the emergency determining system may determine a level, a geographic area, and/or a response to the emergency and to broadcast, via the cellular or mobile network, notifications to individual's personal electronic devices within the geographic area to alert the individuals to the emergency and to provide instructions related to an appropriate response by the individual.