Patents by Inventor Rayomand J. Unwalla

Rayomand J. Unwalla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Toll-like receptor agonists
    Patent number: 11976064
    Abstract: The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: May 7, 2024
    Assignee: Pfizer Inc.
    Inventors: Omar Ahmad, Andrew Fensome, Erik Alphie LaChapelle, Ethan Lawrence Fisher, Rayomand J. Unwalla, Jun Xiao, Lei Zhang
  • TOLL-LIKE RECEPTOR AGONISTS
    Publication number: 20220274986
    Abstract: The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.
    Type: Application
    Filed: May 6, 2022
    Publication date: September 1, 2022
    Applicant: Pfizer Inc.
    Inventors: Omar Ahmad, Andrew Fensome, Erik Alphie LaChapelle, Ethan Lawrence Fisher, Rayomand J. Unwalla, Jun Xiao, Lei Zhang
  • Toll-like receptor agonists
    Patent number: 11339159
    Abstract: The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: May 24, 2022
    Assignee: Pfizer Inc.
    Inventors: Omar Ahmad, Andrew Fensome, Erik Alphie LaChapelle, Ethan Lawrence Fisher, Rayomand J. Unwalla, Jun Xiao, Lei Zhang
  • TOLL-LIKE RECEPTOR AGONISTS
    Publication number: 20210017172
    Abstract: The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.
    Type: Application
    Filed: July 13, 2020
    Publication date: January 21, 2021
    Applicant: Pfizer Inc.
    Inventors: Omar Ahmad, Andrew Fensome, Erik Alphie LaChapelle, Ethan Lawrence Fisher, Rayomand J. Unwalla, Jun Xiao, Lei Zhang
  • Sulfonamide-substituted indole modulators of RORC2 and methods of use thereof
    Patent number: 10385036
    Abstract: The present invention provides sulfonamide-substituted indoles and Methods of Use Thereof-substituted pyrrolopyridines, pharmaceutical compositions thereof methods of modulating RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such indoles and pharmaceutical compositions thereof.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: August 20, 2019
    Assignee: Pfizer Inc.
    Inventors: Mark Edward Schnute, Andrew Christopher Flick, Peter Jones, Neelu Kaila, Scot Richard Mente, John David Trzupek, Michael L. Vazquez, Goran Mattias Wennerstal, Li Xing, Edouard Zamaratski, Liying Zhang, Rayomand J. Unwalla
  • Methyoxy-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof
    Patent number: 10336748
    Abstract: The present invention provides methoxy-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating ROR? activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 2, 2019
    Assignee: Pfizer Inc.
    Inventors: Mark Edward Schnute, Andrew Christopher Flick, Peter Jones, Neelu Kaila, Scot Richard Mente, John David Trzupek, Michael L. Vazquez, Goran Mattias Wennerstal, Li Xing, Edouard Zamaratski, Liying Zhang, Rayomand J. Unwalla
  • Sulfonamide-Substituted Indole Modulators of RORC2 and Methods of Use Thereof
    Publication number: 20180273504
    Abstract: The present invention provides sulfonamide-substituted indoles and Methods of Use Thereof-substituted pyrro-lopyridines, pharmaceutical compositions thereof methods of modulating RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such indoles and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 29, 2016
    Publication date: September 27, 2018
    Applicant: Pfizer Inc.
    Inventors: Mark Edward Schnute, Andrew Christopher Flick, Peter Jones, Neelu Kaila, Scot Richard Mente, John David Trzupek, Michael L. Vazquez, Goran Mattias Wennerstal, Li Xing, Edouard Zamaratski, Liying Zhang, Rayomand J. Unwalla
  • Methyoxy-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof
    Publication number: 20180002330
    Abstract: The present invention provides methoxy-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating ROR? activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 29, 2016
    Publication date: January 4, 2018
    Applicant: Pfizer Inc.
    Inventors: Mark Edward Schnute, Andrew Christopher Flick, Peter Jones, Neelu Kaila, Scot Richard Mente, John David Trzupek, Michael L. Vazquez, Goran Mattias Wennerstal, Li Xing, Edouard Zamaratski, Liying Zhang, Rayomand J. Unwalla
  • Cinnoline compounds
    Patent number: 7700595
    Abstract: This invention relates generally to cinnoline-based modulators of Liver X receptors (LXRs) and related methods.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: April 20, 2010
    Assignee: Wyeth LLC
    Inventors: Baihua Hu, Jay E. Wrobel, Michael David Collini, Rayomand J. Unwalla
  • Indazoles
    Patent number: 7592363
    Abstract: This invention provides compounds of Formula (I) or (Ia): that are useful in the treatment or inhibition of LXR mediated diseases.
    Type: Grant
    Filed: August 1, 2005
    Date of Patent: September 22, 2009
    Assignee: Wyeth
    Inventors: Robert J. Steffan, Edward M. Matelan, Stephen M. Bowen, John W. Ullrich, Jay E. Wrobel, Edouard Zamaratski, Lars Kruger, Annabel L. Olsen Hedemyr, Aiping Cheng, Tomas Hansson, Rayomand J. Unwalla, Christopher P. Miller, Patrik P. Rhönnstad
  • Quinolines and pharmaceutical compositions thereof
    Patent number: 7576215
    Abstract: This invention provides compounds of formula I that are useful in the treatment or inhibition of LXR mediated diseases.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: August 18, 2009
    Assignee: Wyeth
    Inventors: Michael D. Collini, Robert R. Singhaus, Jr., Baihua Hu, James W. Jetter, Robert L. Morris, David H. Kaufman, Christopher P. Miller, John W. Ullrich, Rayomand J. Unwalla, Jay E. Wrobel, Elaine Quinet, Ponnal Nambi, Ronald C. Bernotas, Merle Elloso
  • Quinoline Acids
    Publication number: 20090069373
    Abstract: This invention relates generally to quinoline-based modulators of Liver X receptors (LXRs) and related methods.
    Type: Application
    Filed: February 28, 2008
    Publication date: March 12, 2009
    Applicant: Wyeth
    Inventors: Jay E. Wrobel, Baihua Hu, Michael David Collini, James Winfield Jetter, Ronald Charles Bernotas, David Harry Kaufman, Robert Ray Singhaus, JR., John William Ullrich, Robert Lester Morris, Rayomand J. Unwalla
  • Design of progesterone receptor ligands
    Patent number: 7496489
    Abstract: This invention relates to progesterone receptor/ligand complex, and related methods and software systems. Methods for designing and/or selecting ligands of the progesterone receptor using the three-dimensional structural coordinates of the progesterone receptor and/or nonsteroidal ligands are disclosed.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: February 24, 2009
    Assignee: Wyeth
    Inventors: Andrea M. Olland, James M. Wilhelm, Karl Malakian, Rayomand J. Unwalla
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Patent number: 7022733
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R?, A, A?, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 21, 2004
    Date of Patent: April 4, 2006
    Assignee: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, David H. Kaufman, Robert L. Morris, Robert R. Singhaus, Jr., John W. Ullrich, Heather A. Harris, James C. Keith, Jr., Leo M. Albert, Rayomand J. Unwalla
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Patent number: 6774248
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: August 10, 2004
    Assignee: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, David H. Kaufman, Robert L. Morris, Robert R. Singhaus, Jr., John W. Ullrich, Heather A. Harris, James C. Keith, Jr., Leo M. Albert, Rayomand J. Unwalla
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20030171428
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 16, 2002
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, David H. Kaufman, Robert L. Morris, Robert R. Singhaus, John W. Ullrich, Heather A. Harris, James C. Keith, Leo M. Albert, Rayomand J. Unwalla