Patents by Inventor Rayomand Unwalla

Rayomand Unwalla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of estrogen receptor-beta complex and uses thereof
    Publication number: 20080227960
    Abstract: This invention is directed to the crystal structure of Estrogen Receptor-? (ER-?) complexed with genistein, and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of ER-?, which may be useful as novel chemotherapeutic agents.
    Type: Application
    Filed: April 13, 2007
    Publication date: September 18, 2008
    Applicant: Genetics Institute, LLC.
    Inventors: William S. Somers, Zhang-Bao Xu, Tatos N. Akopian, Chu-Lai Hsiao, Rayomand Unwalla
  • Method using crystal structure of estrogen receptor-? complex
    Patent number: 7235367
    Abstract: This invention is directed to the crystal structure of Estrogen Receptor-? (ER-?) complexed with genistein, and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of ER-?, which may be useful as novel chemotherapeutic agents.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: June 26, 2007
    Assignee: Genetics Institute, LLC.
    Inventors: William S. Somers, Zhang-Bao Xu, Tatos N. Akopian, Chu-Lai Hsiao, Rayomand Unwalla
  • Cinnoline compounds
    Publication number: 20060252757
    Abstract: This invention relates generally to cinnoline-based modulators of Liver X receptors (LXRs) and related methods.
    Type: Application
    Filed: March 1, 2006
    Publication date: November 9, 2006
    Inventors: Baihua Hu, Jay Wrobel, Michael Collini, Rayomand Unwalla
  • Progesterone receptor structure
    Publication number: 20060074081
    Abstract: This invention relates to progesterone receptor/ligand complexes, and related methods and software systems.
    Type: Application
    Filed: August 19, 2005
    Publication date: April 6, 2006
    Inventors: Andrea Olland, James Wilhelm, Karl Malakian, Rayomand Unwalla
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20060074128
    Abstract: This invention provides estrogen receptor modulators of formula 1, having the structure wherein R, R?, A, A?, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 6, 2006
    Applicant: Wyeth
    Inventors: Christopher Miller, Michael Collini, David Kaufman, Robert Morris, Robert Singhaus, John Ullrich, Heather Harris, James Keith, Leo Albert, Rayomand Unwalla
  • Indazoles useful in treating cardiovascular diseases
    Publication number: 20060030612
    Abstract: This invention provides compounds of Formula (I) or (Ia): that are useful in the treatment or inhibition of LXR mediated diseases.
    Type: Application
    Filed: August 1, 2005
    Publication date: February 9, 2006
    Applicant: Wyeth
    Inventors: Robert Steffan, Edward Matelan, Stephen Bowen, John Ullrich, Jay Wrobel, Edouard Zamaratski, Lars Kruger, Annabel Hedemyr, Aiping Cheng, Tomas Hansson, Rayomand Unwalla, Christopher Miller, Patrik Rhonnstad
  • Quinolines useful in treating cardiovascular disease
    Publication number: 20050131014
    Abstract: This invention provides compounds of formula I that are useful in the treatment or inhibition of LXR mediated diseases.
    Type: Application
    Filed: December 10, 2004
    Publication date: June 16, 2005
    Applicant: Wyeth
    Inventors: Michael Collini, Robert Singhaus, Baihua Hu, James Jetter, Robert Morris, David Kaufman, Christopher Miller, John Ullrich, Rayomand Unwalla, Jay Wrobel, Elaine Quinet, Ponnal Nambi, Ronald Bernotas, Merle Elloso
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20050038107
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R?, A, A?, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 21, 2004
    Publication date: February 17, 2005
    Inventors: Christopher Miller, Michael Collini, David Kaufman, Robert Morris, Robert Singhaus, John Ullrich, Heather Harris, James Keith, Leo Albert, Rayomand Unwalla
  • Crystal structure of estrogen receptor-beta complex and uses thereof
    Publication number: 20020072587
    Abstract: This invention is directed to the crystal structure of Estrogen Receptor-&bgr; (ER-&bgr;) complexed with genistein, and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of ER-&bgr;, which may be useful as novel chemotherapeutic agents.
    Type: Application
    Filed: July 11, 2001
    Publication date: June 13, 2002
    Inventors: William S. Somers, Zhang-Bao Xu, Tatos N. Akopian, Chu-Lai Hsiao, Rayomand Unwalla