Patents by Inventor Raz Yirmiya

Raz Yirmiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION COMPRISING CANNABINOIDS, TERPENES, AND FLAVONOIDS FOR TREATING DEPRESSION
    Publication number: 20230270764
    Abstract: The present invention is directed to a pharmaceutical composition, including a method of using same, such as for treating or attenuating a mood disorder in a subject having a high inflammatory state. The pharmaceutical composition and the method of the invention, in some embodiments thereof, comprise suppressing or inhibiting microglia for treating a mood disorder.
    Type: Application
    Filed: July 14, 2021
    Publication date: August 31, 2023
    Inventor: Raz YIRMIYA
  • MICROGLIA MODULATORS FOR USE IN TREATMENT OF DEPRESSION
    Publication number: 20210077477
    Abstract: The present invention relates to methods for treating a depression condition in a subject, including administering to the subject at least one microglial modulator or a combination thereof. Further provided are methods using a microglial modulator(s) in combination with non-invasive brain stimulation (NIBS), such as electroconvulsive therapy (ECT).
    Type: Application
    Filed: March 27, 2019
    Publication date: March 18, 2021
    Inventor: Raz YIRMIYA
  • TREATMENT OF MOOD AND STRESS RELATED DISORDERS
    Publication number: 20200231689
    Abstract: A pharmaceutical composition and method for treating or attenuating a mood or stress-related disorder in a subject having normal or low inflammatory state is provided. In some embodiments, the pharmaceutical composition and method of the invention comprise activating or stimulating microglia for treatment of mood or stress-related disorder.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 23, 2020
    Inventor: Raz YIRMIYA
  • Treatment of mood and stress related disorders
    Patent number: 10626178
    Abstract: A pharmaceutical composition and method for treating or attenuating a mood or stress-related disorder in a subject having normal or low inflammatory state is provided. In some embodiments, the pharmaceutical composition and method of the invention comprise activating or stimulating microglia for treatment of mood or stress-related disorder.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: April 21, 2020
    Inventor: Raz Yirmiya
  • TREATMENT OF MOOD AND STRESS RELATED DISORDERS
    Publication number: 20180230223
    Abstract: A pharmaceutical composition and method for treating or attenuating a mood or stress-related disorder in a subject having normal or low inflammatory state is provided. In some embodiments, the pharmaceutical composition and method of the invention comprise activating or stimulating microglia for treatment of mood or stress-related disorder.
    Type: Application
    Filed: March 23, 2018
    Publication date: August 16, 2018
    Inventor: Raz YIRMIYA
  • Treatment of mood and stress related disorders
    Patent number: 9950036
    Abstract: A pharmaceutical composition and method for treating or attenuating a mood or stress-related disorder in a subject having normal or low inflammatory state is provided. In some embodiments, the pharmaceutical composition and method of the invention comprise activating or stimulating microglia for treatment of mood or stress-related disorder.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: April 24, 2018
    Inventors: Raz Yirmiya, Tirzah Kreisel
  • TREATMENT OF MOOD AND STRESS RELATED DISORDERS
    Publication number: 20160199448
    Abstract: A pharmaceutical composition and method for treating or attenuating a mood or stress-related disorder in a subject having normal or low inflammatory state is provided. In some embodiments, the pharmaceutical composition and method of the invention comprise activating or stimulating microglia for treatment of mood or stress-related disorder.
    Type: Application
    Filed: August 20, 2014
    Publication date: July 14, 2016
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Raz Yirmiya, Tirzah Kreisel
  • Antisense oligonucleotides against AChE in the treatment of gastrointestinal inflammation disorders
    Patent number: 8722876
    Abstract: AChE antisense oligonucleotides are used as antiinflammatory agents, such oligonucleotides preferably having the sequence of SEQ ID NO:1 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation of the gastrointestinal tract, are described.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: May 13, 2014
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Hermona Soreq, Raz Yirmiya
  • AChE ANTISENSE OLIGONUCLEOTIDE AS AN ANTI-INFLAMMATORY AGENT
    Publication number: 20130018081
    Abstract: Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described.
    Type: Application
    Filed: January 16, 2012
    Publication date: January 17, 2013
    Inventors: Hermona Soreq, Raz Yirmiya, Amir Dori, Gal Ifergane, Michal Ivri
  • Method for assessing trait anxiety by determining cholinergic status
    Patent number: 7494783
    Abstract: The invention provides methods/kits for assessing levels of trait or state anxiety in a subject by comparing genotypes and/or expression patterns at the ACHE, PON1 and/or BChE genes to the genotype and/or expression pattern of the genes in a reference population whose genotype and/or expression pattern of the genes is known or by correlating AChE levels activity to those of PON.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: February 24, 2009
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Hermona Soreq, Ella Sklan, Raz Yirmiya, Keren Ailon, Irit Shapira-Lichter
  • AChE antisense oligonucleotide as an anti-inflammatory agent
    Publication number: 20090005331
    Abstract: Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described.
    Type: Application
    Filed: April 18, 2007
    Publication date: January 1, 2009
    Inventors: Hermona Soreq, Amir Dori, Itzhak Wirguin, Gal Ifergane, Raz Yirmiya
  • Method and kit for assessing anxiety or disposition thereto in a subject
    Publication number: 20070037241
    Abstract: The invention provides methods/kits for assessing levels of trait or state anxiety in a subject by comparing genotypes and/or expression patterns at the ACHE, PON1 and/or BChE genes to the genotype and/or expression pattern of the genes in a reference population whose genotype and/or expression pattern of the genes is known or by correlating AChE levels activity to those of PON.
    Type: Application
    Filed: April 10, 2006
    Publication date: February 15, 2007
    Inventors: Hermona Soreq, Ella Sklan, Raz Yirmiya, Keren Ailon, Irit Shapira-Lichter
  • AChE antisense oligonucleotide as an anti-inflammatory agent
    Publication number: 20060069051
    Abstract: Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described.
    Type: Application
    Filed: July 21, 2005
    Publication date: March 30, 2006
    Inventors: Hermona Soreq, Amir Dori, Itzhak Wirguin, Gal Ifergane, Raz Yirmiya