Patents by Inventor Real Denis

Real Denis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 4h-chromens, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof
    Publication number: 20050176750
    Abstract: The present invention is directed to substituted 4H-chromenes, 2H-chromenes, chromans and analogs thereof, represented by the general Formula (I) wherein R5, A, B, X, Y, Z and dotted lines are defined herein. The present invention also relates to the discovery that compounds having Formula (I) are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
    Type: Application
    Filed: May 16, 2003
    Publication date: August 11, 2005
    Inventors: Sui Cai, Songchun Jiang, Giorgio Attardo, Real Denis, Richard Storer, Rabindra Rej
  • Dioxolane analogs for improved inter-cellular delivery
    Publication number: 20030013660
    Abstract: Dioxolane analogs of the following formula: 1
    Type: Application
    Filed: October 15, 2001
    Publication date: January 16, 2003
    Applicant: Shire BioChem Inc.
    Inventors: Giorgio Attardo, Boulos Zacharie, Rabindra Rej, Jean-Francois Lavallee, Louis Vaillancourt, Real Denis, Sophie Levesque
  • Thiophene integrin inhibitors
    Patent number: 6274620
    Abstract: The present invention comprises compounds that are effective inhibitors of integrins, particularly &agr;v&bgr;3 and &agr;v&bgr;5 integrins. Particularly, the compounds are of formula I and pharmaceutically acceptable salts thereof wherein X,Y1 W, R1 to R5, A and B are defined according to the disclosure herein.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: August 14, 2001
    Assignee: BioChem Pharma Inc.
    Inventors: Denis Labrecque, Giorgio Attardo, Monica Bubenik, Laval Chan, Sylvie Charron, Réal Denis, Guy Falardeau, Serge Lamothe, Patrice Préville, Boulos Zacharie