Patents by Inventor Reason

Reason has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12364637
    Abstract: A medical waste management system including a boom secured to a fixed structure of a medical facility. A waste container defines a waste volume sized to collect liquid waste material received through a suction line under the influence of a vacuum provided by a vacuum pump. The system may include a service head coupled to the boom and including the waste container. A vacuum port is in fluid communication with the waste volume, and discharge and/or cleaning ports also in communication with the waste volume may be provided. The vacuum pump may be integrated with the medical facility, and the system may include an offload pump Integrated with the medical facility and in communication with the discharge port. The waste container may be supported on a mobile cart configured to be removably coupled with the boom. The system may further include a liquid measuring system coupled to the waste container.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: July 22, 2025
    Assignee: Stryker Corporation
    Inventors: Wojciech Kazimierz Timoszyk, Brian MacLachlan, Stephen J. Reasoner
  • Publication number: 20250222191
    Abstract: A waste collection system for collecting medical waste. A mobile rover includes at least one waste container, and a rover controller. A chassis is removably couplable with the mobile rover and includes a vacuum regulator, and a chassis controller. The chassis controller is configured to control operation of the vacuum regulator based on a pressure signal from a pressure sensor disposed on the mobile rover. The chassis may include a control panel configured to receive an input of and display a vacuum level, and the chassis controller may control operation of the vacuum regulator based on the input. The mobile rover may include plural waste containers, and the chassis may include plural vacuum regulators. The chassis controller may control operation of the vacuum regulators on the chassis to independently regulate the vacuum level supplied to each of the waste containers on the mobile rover.
    Type: Application
    Filed: January 16, 2025
    Publication date: July 10, 2025
    Applicant: Stryker Corporation
    Inventors: Stephen J. Reasoner, Bruce Henniges, Steven Carusillo, Brian MacLachlan
  • Publication number: 20250176974
    Abstract: A hand-held robotic system for use with a saw blade, the system including an instrument, a localizer, and a controller. The instrument including a hand-held portion, a blade support coupled to the hand-held portion, and an actuator assembly including a plurality of actuators to move the blade support in three degrees of freedom relative to the hand-held portion to place the blade on a desired plane. The controller capable of determining a pose of the saw blade relative to the desired plane based on a position of each of the plurality of actuators. The controller being further configured to be operable between a first mode allowing the instrument to operate and to control each of the plurality of actuators to maintain the saw blade on the desired plane; and a second mode disabling the instrument based on the pose of the saw blade relative to the desire plane.
    Type: Application
    Filed: February 12, 2025
    Publication date: June 5, 2025
    Applicant: MAKO Surgical Corp.
    Inventors: Timothy J. Bozung, Stephen J. Reasoner, Jeffrey Timmer
  • Publication number: 20250163168
    Abstract: Disclosed herein are novel antibodies, novel agonist peptides, and novel dual agonist peptides. Further disclosed herein are novel antibody conjugates comprising the novel antibodies, novel agonist peptides, and/or novel dual agonist peptides disclosed herein. In some embodiments, the antibodies or antibody conjugates of the invention may be used to treat metabolic diseases.
    Type: Application
    Filed: November 14, 2024
    Publication date: May 22, 2025
    Applicant: PFIZER INC.
    Inventors: James Reasoner APGAR, Robert Gregory DULLEA, Jean-Philippe FORTIN, Allison Nicole LAU, Laura LIN LOHSE, Weixu MENG, Lidia MOSYAK
  • Publication number: 20250154287
    Abstract: Provided herein are antibodies (including antigen-binding fragments thereof) that specifically bind to MIGIS-?, including for example without limitation, bispecific MIGIS-?/CD3 antibodies, other related antibodies, related nucleic acids, uses, and associated methods thereof. The disclosure also provides processes for making, preparing, and producing antibodies disclosed herein, including antibodies that bind to one or both of MIGIS-? and CD3.
    Type: Application
    Filed: November 8, 2024
    Publication date: May 15, 2025
    Inventors: Edward Michael FRANKLIN, Brian Joseph FENNELL, Edwina Catherine STACK, Lidia MOSYAK, James Reasoner APGAR, Jeffrey Raymond CHABOT, Bernard KHOR, Thomas Jay MIKITA, Javier Fernando CHAPARRO-RIGGERS
  • Patent number: 12280198
    Abstract: An autonomous medical waste collection assembly. A base supports a waste canister in fluid communication with a manifold receiver, and a suction pump. A controller is in electronic communication with a powered wheel and configured to transmit a movement signal for a motor to power the powered wheel to move the assembly along a floor surface. The assembly may be operable in an autonomous mode in which the powered wheel automatically moves the assembly along the floor surface, and a manual mode in which resistance from the powered wheel is negated to provide for manual movement of the assembly. The controller may be further configured to steer the assembly based on a current location input signal, and a disposal location input signal from a locator network within the medical facility that is indicative of a location of a disposal station.
    Type: Grant
    Filed: August 18, 2022
    Date of Patent: April 22, 2025
    Assignee: Stryker Corporation
    Inventors: Stephen J. Reasoner, Andy Staats, Brian MacLachlan, Tamitha M. Dollman
  • Patent number: 12280199
    Abstract: A method of operating a waste collection unit including a light assembly separate from a display panel. A vacuum level of the vacuum drawn on a waste canister is measured with a vacuum sensor. The light assembly positioned adjacent a manifold receiver is operated to selectively emit light of a color based on the measured vacuum level. A commanded vacuum level may be received on the display panel, and a colored image indicative of a commanded vacuum level may be displayed on the display panel. The waste collection unit may include plural manifold receivers each configured to receive a manifold. The light assembly that is adjacent the manifold receiver corresponding to the waste canister into which the vacuum is being drawn may be operated to selectively emit light to emit light at different colors or different patterns based on the operating state of the waste collection unit.
    Type: Grant
    Filed: August 18, 2022
    Date of Patent: April 22, 2025
    Assignee: Stryker Corporation
    Inventors: Brian J. MacLachlan, Nathan Hogan, Stephen J. Reasoner, Robert Childers
  • Patent number: 12263965
    Abstract: A frangible manifold is used in connection with flight termination operations and stage separation. The manifold has a first portion and a second portion separated by a frangible portion. An aperture extends through the first, second and third sections. A first ordnance termination line is positioned in at least the first section of the first portion of the manifold. A second ordnance termination line is positioned in at least the second section of the second portion of the manifold. In the event of a flight termination, detonation of one ordnance line causes detonation of the second ordnance line. In the event of stage separation, the manifold splits at the frangible portion and the two ordnance lines are safely separated.
    Type: Grant
    Filed: September 14, 2022
    Date of Patent: April 1, 2025
    Assignee: United Launch Alliance, L.L.C.
    Inventors: Zachary Scott Reasoner, Tyler Mundt
  • Patent number: 12266236
    Abstract: A system for the detection of money laundering activities involving casino slot machines and Video Lottery Terminals (collectively “VLTs/Slot Machines”) using an executable copy of security software installed individually at each participating VLT/Slot Machine. The security software monitors cash in/plays/and cash out on all connected VLTs/Slot Machines. The security software contains an artificial intelligence module that flags “suspicious activity” at all connected VLTs/Slot Machines and keeps an audit trail. The security software will disable/track TITO serial numbers/barcodes of all TITOs printed from VLTs in “silent alarm mode”. TITO serial numbers/barcodes printed in “alarm mode” need to be redeemed at the cashier's cage and will not work in an automated redemption kiosk or Ticket Redemption Unit, and the cashiers are forewarned to require positive identification and complete a Suspicious Activity Report (SARC).
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: April 1, 2025
    Inventors: Robert L. Warren, Jr., Michael D. Clanton, II, Anthony Reason
  • Publication number: 20250073049
    Abstract: A method for designing a uni-compartmental orthopaedic prosthesis includes generating a three-dimensional statistical model of a knee joint, determining a curvature of a section of a bone of the knee joint represented by the three-dimensional statistical model, and designing a section of the uni-compartmental orthopaedic prosthesis corresponding to the section of the bone of the knee joint to have a curvature that matches the curvature of the section of the bone of the knee joint. Additionally, a tibial and femoral uni-compartmental orthopaedic prosthesis are also disclosed, each of which includes a section having a curvature that matches a corresponding section of a corresponding bone of the knee joint represented by the three-dimensional statistical model.
    Type: Application
    Filed: August 23, 2024
    Publication date: March 6, 2025
    Inventors: Mark Reason, Mathew Walkington, James Brewerton, David R. Wolfson, Alice De Courcy-Grylls, Robert Freeman
  • Patent number: 12239775
    Abstract: A waste collection system for collecting medical waste. A mobile rover includes at least one waste container, and a rover controller. A chassis is removably couplable with the mobile rover and includes a vacuum regulator, and a chassis controller. The chassis controller is configured to control operation of the vacuum regulator based on a pressure signal from a pressure sensor disposed on the mobile rover. The chassis may include a control panel configured to receive an input of and display a vacuum level, and the chassis controller may control operation of the vacuum regulator based on the input. The mobile rover may include plural waste containers, and the chassis may include plural vacuum regulators. The chassis controller may control operation of the vacuum regulators on the chassis to independently regulate the vacuum level supplied to each of the waste containers on the mobile rover.
    Type: Grant
    Filed: September 13, 2022
    Date of Patent: March 4, 2025
    Assignee: Stryker Corporation
    Inventors: Stephen J. Reasoner, Bruce Henniges, Steven Carusillo, Brian MacLachlan
  • Publication number: 20250064097
    Abstract: A method of making a vegetable- and/or fruit-containing snack food is described. The snack food includes a rigid starch matrix that contains potato starch and a plurality of individual pieces of vegetable and/or fruit randomly distributed throughout the matrix. At least 50% by number of the pieces have a minimum dimension of at least 0.75 mm and a maximum dimension of up to 7 mm. The matrix includes a first cellular structure of first cellular pores having a first pore size distribution and the pieces include a second cellular structure of second cellular pores having a second pore size distribution. At least some of the second cellular pores are defined by polysaccharide cell walls of the respective vegetable and/or fruit. The first pore size distribution has a larger number-average pore size and a wider distribution than the second pore size distribution.
    Type: Application
    Filed: November 11, 2024
    Publication date: February 27, 2025
    Inventors: Debora Saibene, Rebecca Reason
  • Patent number: 12232744
    Abstract: A system is provided comprising a robotic instrument for use with a tool. In some versions, the robotic instrument comprises a hand-held portion to be held by a user and a tool support movably coupled to the hand-held portion to support the tool. A plurality of actuators operatively interconnect the tool support and the hand-held portion to move the tool support in three degrees of freedom relative to the hand-held portion. An optional constraint assembly may operatively interconnect the tool support and the hand-held portion to constrain movement of the tool support relative to the hand-held portion in three degrees of freedom. A guidance array assists users in positioning the tool and/or portions of the instrument.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: February 25, 2025
    Assignee: Stryker Corporation
    Inventors: Timothy J. Bozung, Stephen J. Reasoner, Jeffrey Timmer
  • Publication number: 20240398391
    Abstract: A cassette for collecting a tissue sample. The cassette includes a housing configured to be removably coupled with a manifold receiver of a medical fluid collection system. The housing defines a first void space, a second void space, and an outlet opening. A catch tray is removably positionable within the first void space and includes a screen defining porous features for collecting the tissue sample. A filter element separate from the catch tray is disposed within the second void space. The housing may include a cap portion defining the first void space, and a shell portion coupled to the cap portion and defining the second void space. The cassette may be simultaneously operable in a tissue collection mode in which fluid is suctioned across the catch tray to collect the tissue sample, and a bypass mode in which the fluid is not suctioned across the catch tray.
    Type: Application
    Filed: March 1, 2024
    Publication date: December 5, 2024
    Applicant: Stryker Corporation
    Inventors: Brian James VanDerWoude, Brian MacLachlan, Stephen Isham, Stephen J. Reasoner, David E. Hershberger, Chad Drake, Benjamin Edinger
  • Publication number: 20240360214
    Abstract: The invention is directed to Anti-LILRB1 and anti-LILRB2 bispecific antibodies, anti-LILRB1 antibodies, and anti-LILRB2 antibodies, their uses and pharmaceutical compositions thereof.
    Type: Application
    Filed: April 18, 2024
    Publication date: October 31, 2024
    Applicant: PFIZER INC.
    Inventors: James Reasoner APGAR, Wei CAO, Timothy HEMESATH, Christina Lynn O'HALLORAN, Lan WU, Ming ZHU
  • Publication number: 20240295508
    Abstract: There is provided a method for inspecting and measuring one or more installed one-sided fasteners in a structure. The method includes positioning an X-ray imaging system at a first side of the structure at a location of the one or more installed one-sided fasteners. The method further includes emitting X-rays at the first side of the structure, detecting backscatter from the one or more installed one-sided fasteners, and generating image data from the X-ray imaging system in response to detecting the backscatter. The method further includes measuring and analyzing the image data, with an image processing system, to obtain one or more measurements of one or more dimensions of the one or more installed one-sided fasteners. The method further includes using the image data to inspect the one or more installed one-sided fasteners, and to detect any inconsistencies in the one or more measurements of the one or more dimensions.
    Type: Application
    Filed: March 1, 2023
    Publication date: September 5, 2024
    Applicant: The Boeing Company
    Inventor: Nicholas C. Reasoner
  • Publication number: 20240117030
    Abstract: The present invention relates to antibodies that specifically bind to one or more of IL-4, IL-13, IL-33, TSLP, and p40. The present invention further relates to antibodies that bind to one of IL-4, IL-13, IL-33, or TSLP. The invention further relates to multispecific antibodies that specifically bind to IL-4 and IL-13, and at least one other target. The present invention relates to multispecific antibodies that bind IL-4, IL-13, and one of IL-33, TSLP, or p40. The present invention also pertains to related molecules, e.g. nucleic acids which encode such antibodies or multispecific antibodies, compositions, and related methods, e.g., methods for producing and purifying such antibodies and multispecific antibodies, and their use in diagnostics and therapeutics.
    Type: Application
    Filed: February 28, 2023
    Publication date: April 11, 2024
    Inventors: Rita Diane AGOSTINELLI, James Reasoner APGAR, Eric Matthew BENNETT, Laird BLOOM, Ting CHEN, Aaron Michael D'ANTONA, Arnab DE, Fang JIN, Marion Teresa KASAIAN, Matthew Allister LAMBERT, Kimberly Ann MARQUETTE, Virginie MCMANUS, Jessica Haewon MIN DEBARTOLO, Nicole Melissa PICHE-NICHOLAS, Richard Thomas SHELDON, Lioudmila TCHISTIAKOVA, Alexander Michael Shuford BARRON, Richard Lee GIESECK, III, Xiaotian ZHONG
  • Patent number: 11944278
    Abstract: A cassette for collecting a tissue sample. The cassette includes a housing configured to be removably coupled with a manifold receiver of a medical fluid collection system. The housing defines a first void space, a second void space, and an outlet opening. A catch tray is removably positionable within the first void space and includes a screen defining porous features for collecting the tissue sample. A filter element separate from the catch tray is disposed within the second void space. The housing may include a cap portion defining the first void space, and a shell portion coupled to the cap portion and defining the second void space. The cassette may be simultaneously operable in a tissue collection mode in which fluid is suctioned across the catch tray to collect the tissue sample, and a bypass mode in which the fluid is not suctioned across the catch tray.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: April 2, 2024
    Assignee: Stryker Corporation
    Inventors: Brian James VanDerWoude, Brian MacLachlan, Stephen Isham, Stephen J. Reasoner, David E. Hershberger, Chad Drake, Benjamin Edinger
  • Publication number: 20240083991
    Abstract: Antibodies, and antigen-binding fragments thereof, that specifically bind to bone morphogenetic protein-9 (BMP9) are provided. Embodiments include uses, and associated methods of using the antibodies, and antigen-binding fragments thereof.
    Type: Application
    Filed: May 31, 2023
    Publication date: March 14, 2024
    Applicants: Pfizer Inc., The Brigham and Women's Hospital, Inc., The General Hospital Corporation
    Inventors: Paul B. Yu, James Reasoner Apgar, Susan Adam Benard, Stephen Peter Berasi, Christine Huard, Oleg Victorovich Kovalenko, Lidia Mosyak, Xianchun Tang, Kathleen Elisabeth Tumelty, Luca Troncone, Ying Zhong
  • Patent number: 11925489
    Abstract: A method of method of manufacturing a surgical waste collection manifold with a volume collected datum and a rover type to ensure compatibility with a surgical waste collection rover is provided. The surgical waste collection rover including a vacuum pump and a receiver defining an opening. The method includes obtaining a second manifold. The second manifold having a second housing defining a surface, the housing defining a second manifold volume and a second outlet opening in fluid communication with the second manifold volume. The method may further include coupling a second circuit to the surface of the second manifold, the second circuit comprising a second memory device including a third memory bank and a fourth memory bank, the third memory bank including a fifth memory field and the fourth memory bank including a sixth memory field.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: March 12, 2024
    Assignee: Stryker Corporation
    Inventors: Andy Staats, Brian MacLachlan, Grant Westphal, Stephen J. Reasoner