Abstract: The present invention aims to provide reduction of localized fat, particularly for the treatment, prevention or alleviation of gynoid lypodystrophy. The cosmetic composition of the invention comprises: (a) from 4.0 to 27.0% by weight of active ingredients comprising: (i) at least one localized fat reducing agent selected from the group consisting of natural, modified and synthetic substances, (ii) at least one alkaloid, (iii) at least one oil or vegetable extract, (iv) at least one antioxidant, and (v) at least one film forming agent; (b) 6.0 to 32.0% by weight of cosmetically acceptable additives; and (c) q.s.p. 100% by weight of hydrophilic gel-cream base. The invention also comprises a gel-cream formulation for localized fat reduction, as well as the use of said composition or formulation for manufacturing of a cosmetic for the treatment, prevention or alleviation of gynoid lypodystrophy.