Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.

Abstract: A reusable label for infant's bottles or children's cups, comprising a band section and a label section each made from a flexible material, the band section having a male plastic snap at one end thereof with a plurality of female plastic snaps at the other end thereof for securing the band section around an infant's bottle or children's cup, and the label section being in the middle of the band section with the flexible plastic material thereof being removably markable with dry-erase and wet-erase markers for imparting thereto infant or child identifications and prescriptive caretaker information.

Abstract: An exemplary apparatus includes a container configured to hold and dispense a liquid, and a reusable label configured for use with the container. The reusable label includes a flexible band section and a flexible label section. The flexible band section has a length greater than a circumference of the container. The flexible label section is removably markable with dry-erase and wet-erase markers, and may include pre-printed identifying indicia. The reusable label may further include a first snap coupled to a first end of the flexible band section, and a plurality of second snaps coupled to a second end of the flexible band section, wherein each of the second snaps is configured to releasably engage the first snap.

Abstract: A reusable label for infant's bottles or children's cups, comprising a band section and a label section each made from a flexible material, the band section having a male plastic snap at one end thereof with a plurality of female plastic snaps at the other end thereof for securing the band section around an infant's bottle or children's cup, and the label section being in the middle of the band section with the flexible plastic material thereof being removably markable with dry-erase and wet-erase markers for imparting thereto infant or child identifications and prescriptive caretaker information.

Abstract: Methods and systems for determining whether a particular individual is to be granted, among other things, access to information, access to a particular room or other space, or permission to perform a given act or transaction are disclosed. For example, disclosed is an exemplary method that includes performing multiple biometrics tests on the individual to retrieve multiple biometrics test results, performing at least a first data fusion operation on the multiple biometrics test results to determine an identity result, performing at least one biological state test to determine one or more biological state test results of the individual, and conditionally granting authority to the individual based on the identity result and the one or more biological state results.

Abstract: A stabilizing and support accessory is provided for a stiletto heel. A base plate, having a surface contact area significantly greater than that of the heel, is mounted underneath the heel by means of a simple, clip-on attachment, such that the attachment can be easily and quickly mounted on a heel for walking over soft or uneven surfaces, and also quickly removed when not needed. A preferred clip-on attachment is formed of a section of spring steel shaped into an upwardly opening, U-shaped clip and a horizontally opening clip integrally extending from one element of the upwardly opening clip. An alternative form, formed primarily of plastic, is attached by a single, horizontally disposed clip gripping the heel. The accessories are sufficiently inexpensive that they may be discarded after use, as after walking on muddy surfaces, for example.

Abstract: A method of photo display comprises electronically selecting at least one photo from a memory and electronically arranging at least one electronic photo sheet template, including arranging the at least one photo on the template, into a manipulable configuration for producing a three-dimensional photo display.

Abstract: Compounds of formula (I): wherein: A1 is phenyl, a six-membered aromatic heterocycle containing one, two or three nitrogen atoms, or a five-membered aromatic heterocycle containing up to four heteroatoms chosen from O, N and S, at most one heteroatom being O or S; A2 is phenyl, a six-membered aromatic heterocycle containing one, two or three nitrogen atoms, or a five-membered aromatic heterocycle containing up to four heteroatoms chosen from O, N and S, at most one heteroatom being O or S; L is a bond or C1-6alkylene; R1 and R2 independently chosen from hydrogen and C1-6alkyl or R1 and R2 may, together, form a methylene or ethylene bridge; W is halogen, C1-6alkyl, haloC1-6alkyl, C1-6alkoxy or haloC1-6alkoxy; X is O, S or NR3 or X, together with the atom to which it is attached, and Y, form an unsaturated five-membered ring together with A2; Y is a bond, C1-4alkylene, NH or NH(CH2)1-3; or a pharmaceutically acceptable salt thereof; other substituents are defined in claim 1; which are useful as therapeutic comp

Abstract: An authentication system incorporates pluralilty of fused biometric modalities which are combined with quality indicia of the biometric samples. Fusion processing maps individual modality data along with one or more quality measurements to a fused score for purposes of making an authentication decision.

Abstract: The present invention provides compounds of formula I: in which: one of T1 and T4 is N and the other is C; T2 and T3 are independently N or C(CH2)nR2; X, Y and Z are independently N or C(CH2)nR3; R1 is Ar1 or R1 is C1-6alkyl optionally substituted with one or two groups Ar1; Ar1 is an optionally substituted cyclohexyl, piperidinyl, piperazinyl, morpholinyl, adamantyl, phenyl, naphthyl, a six membered heteroaromatic ring containing one, two or three nitrogen atoms, a five-membered heteroaromatic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one O or S atom being present, or a nine- or ten-membered bicyclic heteroaromatic ring in which phenyl or a six-membered heteroaromatic ring as defined above is fused to a six- or five-membered heteroaromatic ring as defined above; Ar is an optionally substituted phenyl, a six-membered heteroaromatic ring containing one, two or three nitrogen atoms or a five-membered heteroaromatic ring containing one, two, three or four heteroatoms cho

Abstract: A system, method and apparatus for performing a facial approximation is described. The system includes an acquisition subsystem and a facial approximation algorithm. The method includes the steps of acquiring models of known skulls and a model of a questioned skull, comparing the models of the known skulls with the model of the questioned skull, and removing variation in the facial structure of the questioned skull due to skeletal variation between the known skulls and the questioned skull. The apparatus includes a bony structure software component, a bony structure warping software component, and a soft tissue software component.

Abstract: The present invention provides compounds of formula (I); pharmaceutically acceptable salts and N-oxides thereof in which A, B, D and E are C or N with the proviso that one or more are N, R1, R2, R3, R4, R5 and R6 are simple substituents, n is 0-3 and y is an aryl, heteroaryl, carbocyclyl or fused-carbocyclyl group; as VR-1 antagonists for treating conditions or diseases in which pain and/or inflammation predominates; the use of the same for manufacturing medicaments, pharmaceutical compositions comprising them and methods of treatment utilising them.

Abstract: A method of photo display comprises electronically selecting at least one photo from a memory and electronically arranging at least one electronic photo sheet template, including arranging the at least one photo on the template, into a manipulable configuration for producing a three-dimensional photo display.