Abstract: Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Abstract: The present invention relates to a truncated form of chlorotoxin and chlorotoxin-like protein that are useful for glioma immunotherapy, in particular the treatment of glioblastoma. Thus, the invention also encompasses a therapeutic fusion protein comprising the truncated form of chlorotoxin and chlorotoxin-like protein, its methods of use, and its method of production.

Abstract: The present disclosure provides a device to assist in confined space entry. The device includes a housing including a top surface, a bottom surface opposite the top surface, a first end positioned between the top surface and the bottom surface, and a second end opposite the first end and positioned between the top surface and the bottom surface. The device also includes a channel in the housing extending from the bottom surface in a direction towards the top surface, wherein the channel is between the first end and the second end. The device also includes a first roller rotatably coupled to the first end of the housing via a first pin, and a second roller rotatably coupled to the second end of the housing via a second pin.

Abstract: Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Abstract: Disclosed herein is a handle for a tool head. The handle includes a handle region having a first end and a second end. The handle region includes a first region adjacent the first end and adapted to receive a user's thumb and index finger, the first region including a trigger for actuating the tool head. The handle region also includes a second region adjacent the first region that is adapted to receive the user's middle finger and a first portion of the user's palm, and a third region adjacent the second region and adapted to receive the user's ring finger and a second portion of the user's palm. The handle region also includes a fourth region disposed between the third region and the second end that is adapted to receive the user's pinky finger and a third portion of the user's palm.

Abstract: The present disclosure provides a device to assist in confined space entry. The device includes a housing including a top surface, a bottom surface opposite the top surface, a first end positioned between the top surface and the bottom surface, and a second end opposite the first end and positioned between the top surface and the bottom surface. The device also includes a channel in the housing extending from the bottom surface in a direction towards the top surface, wherein the channel is between the first end and the second end. The device also includes a first roller rotatably coupled to the first end of the housing via a first pin, and a second roller rotatably coupled to the second end of the housing via a second pin.

Abstract: An ergonomic pad includes a bladder formed of a pliable material and a granular material disposed within the bladder and at least partially filling the bladder. A port is coupled to the bladder and configured to enable evacuation of air from the bladder. The bladder also includes a sealable opening distinct from the port to add or remove the granular material.

Abstract: An ergonomic pad includes a bladder formed of a pliable material and a granular material disposed within the bladder and at least partially filling the bladder. A port is coupled to the bladder and configured to enable evacuation of air from the bladder. The bladder also includes a sealable opening distinct from the port to add or remove the granular material.

Abstract: The present disclosure provides a device to assist in confined space entry. The device includes a housing including a top surface, a bottom surface opposite the top surface, a first end positioned between the top surface and the bottom surface, and a second end opposite the first end and positioned between the top surface and the bottom surface. The device also includes a channel in the housing extending from the bottom surface in a direction towards the top surface, wherein the channel is between the first end and the second end. The device also includes a first roller rotatably coupled to the first end of the housing via a first pin, and a second roller rotatably coupled to the second end of the housing via a second pin.

Abstract: A pin field, comprising a plurality of pins mounted parallel with each other in a frame. The plurality of pins are extendable and retractable from the frame for sensing an object or for manipulation of the object in a working environment wherein a distal end of each pin in the plurality of pins comprises a combination pressure and temperature sensor.

Abstract: Disclosed herein is a handle for a tool head. The handle includes a handle region having a first end and a second end. The handle region includes a first region adjacent the first end and adapted to receive a user's thumb and index finger, the first region including a trigger for actuating the tool head. The handle region also includes a second region adjacent the first region that is adapted to receive the user's middle finger and a first portion of the user's palm, and a third region adjacent the second region and adapted to receive the user's ring finger and a second portion of the user's palm. The handle region also includes a fourth region disposed between the third region and the second end that is adapted to receive the user's pinky finger and a third portion of the user's palm.

Abstract: Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Abstract: The present disclosure provides a device to assist in confined space entry. The device includes a housing including a top surface, a bottom surface opposite the top surface, a first end positioned between the top surface and the bottom surface, and a second end opposite the first end and positioned between the top surface and the bottom surface. The device also includes a channel in the housing extending from the bottom surface in a direction towards the top surface, wherein the channel is between the first end and the second end. The device also includes a first roller rotatably coupled to the first end of the housing via a first pin, and a second roller rotatably coupled to the second end of the housing via a second pin.

Abstract: Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Abstract: A pin field, comprising a plurality of pins mounted parallel with each other in a frame. The plurality of pins are extendable and retractable from the frame for sensing an object or for manipulation of the object in a working environment.

Abstract: Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Abstract: A tool hand cart incorporates a body with a pair of wheels rotatably mounted on opposite sides of the body proximate a lower rear edge of the body. A collapsible handle is retractably extendable upward from the body. A pair of arms having vertically oriented channels extends from a front of the body and are arranged in spaced relation to define opposing first and second slots configured to receive side frame members of a drill. The handle is retractable to a first position enhancing insertion of the drill and extendible to a second position and the body is configured to tilt from an upright standing position to a canted position in which the body is supported by the pair of wheels and rolled by pulling the handle to thereby transport a drill positioned in the first and second slots.

Abstract: A tool hand cart incorporates a body with a pair of wheels rotatably mounted on opposite sides of the body proximate a lower rear edge of the body. A collapsible handle is retractably extendable upward from the body. A pair of arms having vertically oriented channels extends from a front of the body and are arranged in spaced relation to define opposing first and second slots configured to receive side frame members of a drill. The handle is retractable to a first position enhancing insertion of the drill and extendible to a second position and the body is configured to tilt from an upright standing position to a canted position in which the body is supported by the pair of wheels and rolled by pulling the handle to thereby transport a drill positioned in the first and second slots.

Abstract: A tool hand cart incorporates a body with a pair of wheels rotatably mounted on opposite sides of the body proximate a lower rear edge of the body. A collapsible handle is retractably extendable upward from the body. A pair of arms having vertically oriented channels extends from a front of the body and are arranged in spaced relation to define opposing first and second slots configured to receive side frame members of a drill. The handle is retractable to a first position enhancing insertion of the drill and extendible to a second position and the body is configured to tilt from an upright standing position to a canted position in which the body is supported by the pair of wheels and rolled by pulling the handle to thereby transport a drill positioned in the first and second slots.

Abstract: A tool hand cart incorporates a body with a pair of wheels rotatably mounted on opposite sides of the body proximate a lower rear edge of the body. A collapsible handle is retractably extendable upward from the body. A pair of arms having vertically oriented channels extends from a front of the body and are arranged in spaced relation to define opposing first and second slots configured to receive side frame members of a drill. The handle is retractable to a first position enhancing insertion of the drill and extendible to a second position and the body is configured to tilt from an upright standing position to a canted position in which the body is supported by the pair of wheels and rolled by pulling the handle to thereby transport a drill positioned in the first and second slots.