Patents by Inventor Rebecca E. McCoy

Rebecca E. McCoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mammalian cell culture
    Patent number: 11827692
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell o growth to achieve high product titer cell cultures.
    Type: Grant
    Filed: March 8, 2023
    Date of Patent: November 28, 2023
    Assignee: AMGEN INC.
    Inventors: Brian D. Follstad, Rebecca E. McCoy, Arvia E. Morris
  • MAMMALIAN CELL CULTURE
    Publication number: 20230227535
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell o growth to achieve high product titer cell cultures.
    Type: Application
    Filed: March 8, 2023
    Publication date: July 20, 2023
    Applicant: AMGEN INC.
    Inventors: Brian D. FOLLSTAD, Rebecca E. McCOY, Arvia E. MORRIS
  • Mammalian cell culture
    Patent number: 11685772
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Grant
    Filed: December 14, 2022
    Date of Patent: June 27, 2023
    Assignee: AMGEN INC.
    Inventors: Brian D. Follstad, Rebecca E. McCoy, Arvia E. Morris
  • Mammalian cell culture
    Patent number: 11673941
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: June 13, 2023
    Assignee: AMGEN INC.
    Inventors: Brian D. Follstad, Rebecca E. McCoy, Arvia E. Morris
  • MAMMALIAN CELL CULTURE
    Publication number: 20230129523
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell o growth to achieve high product titer cell cultures.
    Type: Application
    Filed: December 20, 2022
    Publication date: April 27, 2023
    Applicant: AMGEN INC.
    Inventors: Brian D. FOLLSTAD, Rebecca E. McCOY, Arvia E. MORRIS
  • Mammalian cell culture
    Patent number: 11634476
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: April 25, 2023
    Assignee: AMGEN INC.
    Inventors: Brian D. Follstad, Rebecca E. McCoy, Arvia E. Morris
  • MAMMALIAN CELL CULTURE
    Publication number: 20230117598
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Application
    Filed: December 14, 2022
    Publication date: April 20, 2023
    Applicant: AMGEN INC.
    Inventors: Brian D. FOLLSTAD, Rebecca E. McCOY, Arvia E. MORRIS
  • MAMMALIAN CELL CULTURE
    Publication number: 20220185869
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Application
    Filed: March 4, 2022
    Publication date: June 16, 2022
    Applicant: Amgen Inc.
    Inventors: Brian D. FOLLSTAD, Rebecca E. McCOY, Arvia E. MORRIS
  • Mammalian cell culture
    Patent number: 11292829
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures by changing the temperature of the cell culture and/or by starving the cells in their asparagine supply.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: April 5, 2022
    Assignee: AMGEN INC.
    Inventors: Brian D. Follstad, Rebecca E. McCoy, Arvia E. Morris
  • MAMMALIAN CELL CULTURE
    Publication number: 20210061888
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Application
    Filed: September 11, 2020
    Publication date: March 4, 2021
    Applicant: Amgen Inc.
    Inventors: Brian D. FOLLSTAD, Rebecca E. McCOY, Arvia E. MORRIS
  • MAMMALIAN CELL CULTURE
    Publication number: 20200407427
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Applicant: Amgen Inc.
    Inventors: Brian D. FOLLSTAD, Rebecca E. McCOY, Arvia E. MORRIS
  • Method for culturing mammalian cells to improve recombinant protein production
    Patent number: 9388447
    Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: July 12, 2016
    Assignee: AMGEN, INC.
    Inventors: Matthew I. Jerums, Amanda Kano, Henry Lin, Shun Luo, Jian Wu, Rebecca E. McCoy, Arvia E. Morris
  • METHOD FOR CULTURING MAMMALIAN CELLS TO IMPROVE RECOMBINANT PROTEIN PRODUCTION
    Publication number: 20160040207
    Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.
    Type: Application
    Filed: August 7, 2015
    Publication date: February 11, 2016
    Applicant: AMGEN INC.
    Inventors: Matthew I. JERUMS, Amanda KANO, Henry LIN, Shun LUO, Jian WU, Rebecca E. McCOY, Arvia E. MORRIS
  • Method for culturing mammalian cells to improve recombinant protein production
    Patent number: 9133493
    Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: September 15, 2015
    Assignee: AMGEN INC.
    Inventors: Matthew I. Jerums, Amanda Kano, Henry Lin, Shun Luo, Jian Wu, Rebecca E. McCoy, Arvia E. Morris
  • Dipeptides to enhance yield and viability from cell cultures
    Patent number: 9012178
    Abstract: The present invention relates to the culture of animal cells in serum-free culture medium. The present invention provides particular dipeptides that can improve recombinant protein production and cell viability in such cultures, especially in the absence of peptones.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: April 21, 2015
    Assignee: Amgen Inc.
    Inventors: Sohye Kang, Rohini Deshpande, Rebecca E. McCoy, Leslie P. Miranda, Arvia E. Morris
  • MAMMALIAN CELL CULTURE
    Publication number: 20140255993
    Abstract: The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures by changing the temperature of the cell culture and/or by starving the cells in their asparagine supply.
    Type: Application
    Filed: June 29, 2012
    Publication date: September 11, 2014
    Applicant: AMGEN INC.
    Inventors: Brian D. Follstad, Rebecca E. McCoy, Arvia E. Morris
  • METHOD FOR CULTURING MAMMALIAN CELLS TO IMPROVE RECOMBINANT PROTEIN PRODUCTION
    Publication number: 20140178984
    Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.
    Type: Application
    Filed: April 20, 2012
    Publication date: June 26, 2014
    Applicant: AMGEN INC.
    Inventors: Matthew I. Jerums, Amanda Kano, Henry Lin, Shun Luo, Jian Wu, Rebecca E. McCoy, Arvia E. Morris
  • DIPEPTIDES TO ENHANCE YIELD AND VIABILITY FROM CELL CULTURES
    Publication number: 20130189737
    Abstract: The present invention relates to the culture of animal cells in serum-free culture medium. The present invention provides particular dipeptides that can improve recombinant protein production and cell viability in such cultures, especially in the absence of peptones.
    Type: Application
    Filed: August 5, 2011
    Publication date: July 25, 2013
    Applicant: AMGEN INC.
    Inventors: Sohye Kang, Rohini Deshpande, Rebecca E. McCoy, Leslie P. Miranda, Arvia E. Morris
  • METHOD FOR CULTURING MAMMALIAN CELLS TO IMPROVE RECOMBINANT PROTEIN PRODUCTION
    Publication number: 20100221823
    Abstract: The present invention relates to methods for mammalian cell culture, wherein the methods make use of media containing polyamines, such as putrescine, spermidine and spermine.
    Type: Application
    Filed: June 10, 2008
    Publication date: September 2, 2010
    Applicant: Amgen Inc.
    Inventors: Rebecca E. McCoy, Arvia E. Morris
  • Increased recovery of active proteins
    Patent number: 7544784
    Abstract: The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: June 9, 2009
    Assignee: Immunex Corporation
    Inventors: Helmut M. Sassenfeld, Richard L. Remmele, Jr., Rebecca E. McCoy