Abstract: An expandable writing instrument has a writing end body section and a rear body section mounted to the writing end body section for relative axial and non-rotational movement between an extended position with the rear body section spaced away from the writing end body section, and a retracted position with the rear body section closer to the writing end body section. A spring in the writing end body section biases the cartridge upwardly. A helix cylinder is mounted for rotation and axial movement in the rear body section with a peg of the rear body section sliding in a track of the helix cylinder. The track is a closed loop with left and right hand helixes so that axial movement of the rear body section causes rotation of the helix cylinder continuously in one rotational direction. A shuttle receives a cartridge body and is mounted for axial movement in the helix cylinder. A shuttle cam on the shuttle is mounted for axial non-rotational movement to the writing end body section.

Abstract: An expandable writing instrument has a writing end body section and a rear body section mounted to the writing end body section for relative axial and non-rotational movement between an extended position with the rear body section spaced away from the writing end body section, and a retracted position with the rear body section closer to the writing end body section. A spring in the writing end body section biases the cartridge upwardly. A helix cylinder is mounted for rotation and axial movement in the rear body section with a peg of the rear body section sliding in a track of the helix cylinder. The track is a closed loop with left and right hand helixes so that axial movement of the rear body section causes rotation of the helix cylinder continuously in one rotational direction. A shuttle receives a cartridge body and is mounted for axial movement in the helix cylinder. A shuttle cam on the shuttle is mounted for axial non-rotational movement to the writing end body section.

Abstract: The present invention discloses new and useful compounds including methyl p-hydroxyphenyllactate, its analogues, chemical derivatives and chemically related compounds and their use as antitumor agents, as inhibitors of proliferative cell growth and as prophylactic agents to inhibit and prevent cancer and non-malignant cell growth.