Patents by Inventor Rebecca Guggemos Bakker-Arkema

Rebecca Guggemos Bakker-Arkema has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of congestive heart failure
    Patent number: 7192951
    Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine. Preferred vasopressin antagonists have the formula wherein R and R5 are hydrogen or lower alkyl; R1, R2, and R3 are hydrogen, halo, alkyl, alkoxy, and amino; and R4 is hydrogen or phenyl, and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: March 20, 2007
    Assignee: Astellas Pharma Inc.
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Selective manipulation of triglyceride, HDL and LDL parameters with 6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethylhexanoic acid monocalcium salt
    Publication number: 20040229954
    Abstract: Methods for selectively modulating triglyceride, high-density lipoprotein, and low-density lipoprotein levels in a patient by administering a certain dose of 6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethylhexanoic acid monocalcium salt are disclosed.
    Type: Application
    Filed: May 13, 2004
    Publication date: November 18, 2004
    Inventors: Diane Elaine MacDougall, Rebecca Guggemos Bakker-Arkema
  • Treatment of congestive heart failure
    Publication number: 20040176354
    Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine.
    Type: Application
    Filed: March 12, 2004
    Publication date: September 9, 2004
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Method for treating postoperative ileus
    Patent number: 6645959
    Abstract: This invention is a method for preventing or treating postoperative ileus comprising administering a vasopressin antagonist such as a compound of Formula (1), where R1, R2, and R3 include hydrogen, halo, alkyl, and alkoxy; R and R5 are hydrogen or alkyl; R4 is hydrogen, phenyl, or substituted phenyl, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: November 11, 2003
    Assignee: Warner-Lambert Company
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Treatment of congestive heart failure
    Publication number: 20030008860
    Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine.
    Type: Application
    Filed: May 9, 2002
    Publication date: January 9, 2003
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler