Abstract: Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof.

Abstract: Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof.

Abstract: An apparatus and a method for an ultrasonic medical device to treat urolithiasis and ablate a stone. The ultrasonic medical device comprises an ultrasonic probe having a wire body with a proximal end, a distal end and a longitudinal axis therebetween and a plurality of tines extending from the distal end of the wire body. The ultrasonic medical device includes a sheath capable of surrounding the wire body and the plurality of tines. The ultrasonic probe is inserted into the sheath and the ultrasonic probe is moved until the plurality of tines surround at least a portion of an outer surface of the stone. An ultrasonic energy source engaged to the ultrasonic probe supplies an ultrasonic energy to the ultrasonic probe to produce a transverse ultrasonic vibration along at least a portion of the ultrasonic probe to ablate the stone.

Abstract: The present invention provides an apparatus and a method for an ultrasonic probe capable of bending, flexing and deflecting with the aid of a balloon to remove a biological material. An ultrasonic medical device includes a balloon catheter, a balloon that is supported by the balloon catheter, an inflation lumen located along a longitudinal axis of the balloon catheter and an ultrasonic probe located along an outside surface of the balloon catheter wherein the ultrasonic probe engages an outer surface of the balloon. The ultrasonic probe is inserted through at least one engaging mechanism on an outside surface of the balloon catheter. The inflated balloon causes the ultrasonic probe to bend, allowing the ultrasonic probe to move along a bend in a vasculature and increase a surface area of the ultrasonic probe in communication with the biological material for ablation.

Abstract: The present invention provides an apparatus and a method for an ultrasonic medical device operating in a torsional mode to treat a biological material. An ultrasonic probe of the ultrasonic medical device is placed in communication with the biological material. An ultrasonic energy source is activated to produce an electrical signal that drives a transducer to produce a torsional vibration of the ultrasonic probe. The torsional vibration produces a rotation and a counterrotation along the longitudinal axis of the ultrasonic probe that creates a plurality of torsional nodes and a plurality of torsional anti-nodes along a portion of the longitudinal axis of the ultrasonic probe resulting in cavitation along a portion of the longitudinal axis of the ultrasonic probe comprising a radially asymmetric cross section that ablates the biological material.

Abstract: The present invention provides an apparatus and a method for an ultrasonic medical device operating in a torsional mode and a transverse mode. An ultrasonic probe of the ultrasonic medical device is placed in communication with a biological material. An ultrasonic energy source is activated to produce an electrical signal that drives a transducer to produce a torsional vibration of the ultrasonic probe. The torsional vibration produces a component of force in a transverse direction relative to a longitudinal axis of the ultrasonic probe, thereby exciting a transverse vibration along the longitudinal axis causing the ultrasonic probe to undergo both a torsional vibration and a transverse vibration. The torsional vibration and the transverse vibration cause cavitation in a medium surrounding the ultrasonic probe to ablate the biological material.

Abstract: The present invention provides an apparatus and a method for an ultrasonic medical device having a flexible material engaging an ultrasonic probe. The flexible material surrounds a portion of a longitudinal axis of an ultrasonic probe of the ultrasonic medical device. The flexible material may extend beyond a probe tip. The flexible material cushions a tip of the ultrasonic probe and reduces the stresses on the ultrasonic probe as the ultrasonic probe is navigated within the vasculature. The ultrasonic probe may be shaped to increase a radial span of the ultrasonic medical device. In a preferred embodiment of the present invention, the flexible material comprises a polymer material. Additionally, the flexible material may have a high radiopacity.