Abstract: A Data Security Management System using a communications interface configured to receive and transmit one or more portions of Post Quantum Resistant Encrypted data within a network comprising a plurality of endpoints. Using End-to-End (E2E) Post Quantum Resistant encryption techniques to protect the data, the Data Security Management System provides the flexibility for multiple data schemes in a distributive environment such as, but not limited to, Hyperledger. The system uses a Policy Manager to perform the base configuration of the session to be transmitted or received in an encrypted state. This encrypted state comprises Post Quantum Cryptographic algorithm in use for that session, inclusive with associated keys or digital signatures. The Policy Manager is further configured to verify an identity of endpoint by a multifactor cryptographic authentication mechanism or a biometric authentication mechanism to validate a connection to or from an endpoint.

Abstract: The presently disclosed subject matter provides devices, systems, and methods for model inter-organ communication. In some embodiments, a multi-organ-on-a-chip (MOC) system can include one or more micro-culture well configured to receive a live tissue sample therein and an impeller-based pump in fluid communication with the one or more micro-culture well. In this arrangement, the impeller-based pump can be configured to generate fluid flow through the one or more micro-culture well.

Abstract: A processor may identify one or more data fields of interest. The processor may receive data for each of the data fields of interest. The processor may compute one or more bias scores for the data fields of interest based on the data. The processor may develop a bias matrix with the bias scores. The processor may display the bias matrix to a user.

Abstract: Embodiments include a method, system and computer program product for detecting impersonation attempts in social media messaging. Aspects include receiving, via a social media network, a message from a sender to a recipient and analyzing a content of the message to extract factual statements from the message. Aspects also include analyzing a profile of the recipient to extract facts from the profile and comparing each of the factual statements to the facts from the profile. Based on a determination that one of the factual statements are verifiable by at least one of the facts, aspects include assigning a likelihood score to the factual statements. Aspects further include calculating a legitimacy score for the message based at least in part on the likelihood score of each verified factual statement from the message and transmitting the legitimacy score and the message to the recipient.

Abstract: The present invention relates to high-throughput methods comprising direct infusion electrospray ionization mass spectrometry (ESI-MS), multistep tandem mass spectrometry (MSn), consecutive reaction monitoring (CRM), ion mobility spectrometry mass spectrometry (IMS-MS), high-resolution MS, and IMS-MS, for genome-wide (whole cell or tissue) profiling of DNA and RNA nucleotides/nucleosides having a wide variety of variant structural modifications. In particular, these methods are contemplated for providing a specific profile of variant DNA and/or RNA chemically modified nucleic acids (i.e. structures) associated with specific medical conditions. Medical conditions may include, but are not limited to: cancer; including prostate, lung, uterus, larynx, ovary, breast, kidney, and many other types of cancers; specific stages of cancer; bacterial infections; viral infections; genetic and metabolic disorders; and any condition involving changes in DNA and/or RNA structural modifications.

Abstract: A Data Security Management System using a communications interface configured to receive and transmit one or more portions of Post Quantum Resistant Encrypted data within a network comprising a plurality of endpoints. Using End-to-End (E2E) Post Quantum Resistant encryption techniques to protect the data, the Data Security Management System provides the flexibility for multiple data schemes in a distributive environment such as, but not limited to, Hyperledger. The system uses a Policy Manager to perform the base configuration of the session to be transmitted or received in an encrypted state. This encrypted state comprises Post Quantum Cryptographic algorithm in use for that session, inclusive with associated keys or digital signatures. The Policy Manager is further configured to verify an identity of endpoint by a multifactor cryptographic authentication mechanism or a biometric authentication mechanism to validate a connection to or from an endpoint.

Abstract: Disclosed is a computer implemented method to identify relevant feedback. The method includes training, with a set of training data, a generative adversarial network (GAN), wherein the GAN includes a generator and a discriminator, and the set of training data is comprised of a plurality of feedback, each instance of feedback includes a value in a plurality of categories, the categories including a positivity value, and a validity value. The method also includes receiving, from a user, a new instance of feedback. The method further includes determining, by the discriminator, a first validity value and a first positivity value of the new instance of feedback. The method includes updating, in response to the first validity value being valid, and the first positivity value being negative, the GAN. The method further includes, displaying the new instance of feedback.

Abstract: Provided are microfluidic chip-based models of immune system tissues. In some embodiments, the models include a microfluidic housing having a cell culture chamber and one or more channels in communication with the cell culture chamber and a cell culture residing in the cell culture chamber, wherein the cell culture includes one or more cells of the immune system. Also provided are systems that include one or more microfluidic chip-based models of immune system tissues, methods for patterning cells in culture on microfluidic chips, and methods for modeling immune responses of subjects using the same.

Abstract: Provided are devices for carrying out reactions, which in some embodiments can include a plurality of first, second, third, and fourth reservoirs disposed on first and second surfaces, wherein the first and second surfaces are configured to move relative in to each other between first, second, third, fourth, and fifth positions to expose the first, second, third, and fourth reservoirs to each other or isolate the first, second, third, and fourth reservoirs from each other, as desired. In some embodiments, the devices include one or more detection windows that are substantially transparent to light in the ultraviolet (UV)/visible spectrum to allow assaying the extent to which a reaction has proceeded and/or to determine an optimal degree thereof. Also provided are methods for using the disclosed devices for performing reactions including but not limited to conjugation reactions as well as to optimize the same.

Abstract: Embodiments include a method, system and computer program product for detecting impersonation attempts in social media messaging. Aspects include receiving, via a social media network, a message from a sender to a recipient and analyzing a content of the message to extract factual statements from the message. Aspects also include analyzing a profile of the recipient to extract facts from the profile and comparing each of the factual statements to the facts from the profile. Based on a determination that one of the factual statements are verifiable by at least one of the facts, aspects include assigning a likelihood score to the factual statements. Aspects further include calculating a legitimacy score for the message based at least in part on the likelihood score of each verified factual statement from the message and transmitting the legitimacy score and the message to the recipient.

Abstract: A method, computer system, and computer program product for chat protection. The embodiment may include receiving, in a chat session, a user-spoken communication and one or more inputs specific to a software program. The embodiment may also include predicting a next communication by the user based on the received user spoken communication and the one or more inputs. The embodiment may further include, in response to the predicted next communication containing untoward content, performing a remedial action.

Abstract: A method, computer system, and computer program product for chat protection. The embodiment may include receiving, in a chat session, a user-spoken communication and one or more inputs specific to a software program. The embodiment may also include predicting a next communication by the user based on the received user spoken communication and the one or more inputs. The embodiment may further include, in response to the predicted next communication containing untoward content, performing a remedial action.

Abstract: The invention provides for methods, treatments, and uses for anti-human VEGFR-2 antibodies for the treatment of metastatic colorectal cancer in patients having elevated levels of VEGF-D.

Abstract: The present invention relates to high-throughput methods comprising direct infusion electrospray ionization mass spectrometry (ESI-MS), multistep tandem mass spectrometry (MSn), consecutive reaction monitoring (CRM), ion mobility spectrometry mass spectrometry (IMS-MS), high-resolution MS, and IMS-MS, for genome-wide (whole cell or tissue) profiling of DNA and RNA nucleotides/nucleosides having a wide variety of variant structural modifications. In particular, these methods are contemplated for providing a specific profile of variant DNA and/or RNA chemically modified nucleic acids (i.e. structures) associated with specific medical conditions. Medical conditions may include, but are not limited to: cancer; including prostate, lung, uterus, larynx, ovary, breast, kidney, and many other types of cancers; specific stages of cancer; bacterial infections; viral infections; genetic and metabolic disorders; and any condition involving changes in DNA and/or RNA structural modifications.

Abstract: A system and method for using pilot-controllable discretionary operational parameters to reduce fuel consumption in piloted aircraft, for training pilots in use of the system of the invention, and for comparatively rating a particular pilot in relation to plurality of pilots as to the ability to reduce aircraft fuel consumption through the utilization of pilot controllable discretionary operational parameters.

Abstract: A compound and method of using such compound is disclosed that, when administered to an animal, is capable of arresting the inflammatory response in affected tissues and facilitates the repair and maintenance of damaged tissues in the joints of vertebrates. The combination of natural physiological metabolites and herbal phytochemicals is used to treat connective tissue diseases, the composition preferably orally administered. One embodiment of the composition includes chondroitin sulfate and glucosamine that, when ingested by a vertebrate, suppresses the degradation of connective tissue by an autoimmune response. A preferred composition of the present invention includes a palatability agent, an herbal phytochemical, and a metabolic precursor that synergistically acts to increase blood circulation, thereby enhancing transport of the phytochemical and metabolic precursors to an affected site whereby deleterious inflammatory byproducts are removed.

Abstract: A compound and method of using such compound is disclosed that, when administered to an animal, is capable of arresting the inflammatory response in affected tissues and facilitates the repair and maintenance of damaged tissues in the joints of vertebrates. The combination of natural physiological metabolites and herbal phytochemicals is used to treat connective tissue diseases, the composition preferably orally administered. One embodiment of the composition includes chondroitin sulfate and glucosamine that, when ingested by a vertebrate, suppresses the degradation of connective tissue by an autoimmune response. A preferred composition of the present invention includes a palatability agent, an herbal phytochemical, and a metabolic precursor that synergistically acts to increase blood circulation, thereby enhancing transport of the phytochemical and metabolic precursors to an affected site whereby deleterious inflammatory byproducts are removed.

Abstract: A compound and method of using such compound is disclosed that, when administered to an animal, is capable of arresting the inflammatory response in affected tissues and facilitates the repair and maintenance of damaged tissues in the joints of vertebrates. The combination of natural physiological metabolites and herbal phytochemicals is used to treat connective tissue diseases, the composition preferably orally administered. One embodiment of the composition includes chondroitin sulfate and glucosamine that, when ingested by a vertebrate, suppresses the degradation of connective tissue by an autoimmune response. A preferred composition of the present invention includes a palatability agent, an herbal phytochemical, and a metabolic precursor that synergistically acts to increase blood circulation, thereby enhancing transport of the phytochemical and metabolic precursors to an affected site whereby deleterious inflammatory byproducts are removed.

Abstract: A compound and method of using such compound is disclosed that, when administered to an animal, is capable of arresting the inflammatory response in affected tissues and facilitates the repair and maintenance of damaged tissues in the joints of vertebrates. The combination of natural physiological metabolites and herbal phytochemicals is used to treat connective tissue diseases, the composition preferably orally administered. One embodiment of the composition includes chondroitin sulfate and glucosamine that, when ingested by a vertebrate, suppresses the degradation of connective tissue by an autoimmune response. A preferred composition of the present invention includes a palatability agent, an herbal phytochemical, and a metabolic precursor that synergistically acts to increase blood circulation, thereby enhancing transport of the phytochemical and metabolic precursors to an affected site whereby deleterious inflammatory byproducts are removed.

Abstract: A composition and method of use is disclosed that, when administered to an animal, is capable of arresting the inflammatory response in affected tissues and facilitates the repair and maintenance of damaged tissues in the joints of vertebrates. The combination of natural physiological metabolites and herbal phytochemicals is used to treat connective tissue diseases, the composition is preferably orally administered. One embodiment of the composition includes chondroitin sulfate and glucosamine that, when ingested by a vertebrate, suppresses the degradation of connective tissue by an autoimmune response. A composition of the present invention includes a palatability agent, an herbal phytochemical, and a metabolic precursor that act to increase blood circulation, thereby enhancing transport of the phytochemical and metabolic precursors to an affected site whereby deleterious inflammatory byproducts are removed.