Patents by Inventor Rebecca Whipple-Bettes

Rebecca Whipple-Bettes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods for assaying living cells
    Patent number: 11054413
    Abstract: The present invention provides a device for assaying living cells comprising a substrate, wherein the substrate comprises one or more tethering molecules which adhere to the substrate and are capable of interacting with cell membranes of the cells, wherein the cells maintain a free-floating, non-adherent character when bound to the one or more tethering molecules.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: July 6, 2021
    Assignees: UNIVERSITY OF MARYLAND, COLLEGE PARK, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Stuart Martin, Christopher M. Jewell, James I. Andorko, Elisabeth Lily Sooklal, Rebecca Whipple Bettes, Kristi Chakrabarti
  • MATERIALS AND METHODS FOR ASSAYING LIVING CELLS
    Publication number: 20160097769
    Abstract: The present invention provides a device for assaying living cells comprising a substrate, wherein the substrate comprises one or more tethering molecules which adhere to the substrate and are capable of interacting with cell membranes of the cells, wherein the cells maintain a free-floating, non-adherent character when bound to the one or more tethering molecules.
    Type: Application
    Filed: October 7, 2015
    Publication date: April 7, 2016
    Inventors: Stuart Martin, Christopher M. Jewell, James I. Andorko, Elisabeth Lily Sooklal, Rebecca Whipple Bettes, Kristi Chakrabarti
  • Inhibition of microtubule protrusion in cancer cells
    Patent number: 8193238
    Abstract: The present invention generally concerns microtubule protrusions in cancer cells, including detached cancer cells, and inhibition of the protrusions. In particular aspects, the inhibition of the protrusions interferes with attachment of the cell to a vessel wall, and in further aspects the cell is killed by forcing it to enter capillaries and be destroyed, for example by shearing. Inhibition by a variety of agents and methods is contemplated.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: June 5, 2012
    Assignee: University of Maryland, Baltimore
    Inventors: Stuart Martin, Rebecca Whipple-Bettes
  • APOPTOTIC PATHWAY TARGETING FOR THE DIAGNOSIS AND TREATMENT OF CANCER
    Publication number: 20110021440
    Abstract: The invention relates to methods of treating cancer. The invention further relates to a method of treating cancer by exploiting apoptotic pathways. The invention particularly relates to regulation of apoptotic pathways in cancerous cells, to metastasis of cancer cells, and to methods of preventing cancer metastasis.
    Type: Application
    Filed: May 16, 2008
    Publication date: January 27, 2011
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Stuart S. Martin, Anges Cheung, Rebecca Whipple-Bettes
  • INHIBITION OF MICROTUBULE PROTRUSION IN CANCER CELLS
    Publication number: 20090137473
    Abstract: The present invention generally concerns microtubule protrusions in cancer cells, including detached cancer cells, and inhibition of the protrusions. In particular aspects, the inhibition of the protrusions interferes with attachment of the cell to a vessel wall, and in further aspects the cell is killed by forcing it to enter capillaries and be destroyed, for example by shearing. Inhibition by a variety of agents and methods is contemplated.
    Type: Application
    Filed: March 8, 2007
    Publication date: May 28, 2009
    Inventors: Stuart Martin, Rebecca Whipple-Bettes